5-IAI Hi all this is my first post and first trip report on this forum, i am going to make this as accurate, honest and have as much information as possible After reading up about this drug i have really been looking forward to this in some respects but with all the speculation of debatable trip reports out there i app...
5-IAI
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 3 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 18 combo interactions documented
- classified Tentative
- classified Research-chemical
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 3 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 18 combo interactions documented
- classified Tentative
- classified Research-chemical
Aliases: 5-iodo-2-aminoindan, 5iai
Summary
Animal studies show markedly lower serotonergic neurotoxicity than p-iodoamphetamine, but single 40 mg/kg doses still reduced hippocampal 5-HT uptake sites. Human anecdotal reports indicate 5-IAI is less euphoric and stimulating than MDMA, with some users reporting dysphoria, anxiety, and hallucinations at various doses. Many products sold as 5-IAI between 2010-2013 were mislabeled or adulterated; reagent testing is essential.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 15-30mg | 30-50mg | 50-100mg | 100mg+ |
| Insufflated | 5-15mg | 15-35mg | 35-60mg | 60mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 20-45 min | 30-60 min | 1-3 hrs | 2-3 hrs | 3.83-7.75 hrs |
| Insufflated | 5-15 min | 15-30 min | 1-2.5 hrs | 2-3 hrs | 3.33-6.25 hrs |
| Rectal | 10-20 min | 20-40 min | 1-2.5 hrs | 2-3 hrs | 3.5-6.5 hrs |
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Psychedelic
2.9
Light+
3/10
Mild auditory effects with low body load, visuals, and headspace
Visual Intensity
×3
2
visual enhancement
Headspace Depth
×3
2
emotion enhancement
Auditory Effects
×1
4
music enhancement
Body Load / Somatic Effects
×1
3
teeth grinding
sweating
Empathogen
5.9
Strong
6/10
Strong sensory enhancement with moderate euphoria, mild empathy and stimulation
Empathy / Social Openness
×3
5
empathy and sociability
increased sociability
Euphoria / Mood Elevation
×2
7
euphoria
mood lift
emotion enhancement
Stimulation
×1
4
stimulation
teeth grinding
Sensory Enhancement
×1
8
tactile enhancement
music enhancement
visual enhancement
Stimulant
3.2
Light+
3/10
Moderate anxiety/jitters with mild euphoria, low stimulation and focus
Stimulation / Energy
×3
3
stimulation
Euphoria / Mood Lift
×2
5
euphoria
mood lift
Focus / Productivity
×2
2
cognitive enhancement
Anxiety / Jitters
×1
7
anxiety
teeth grinding
sweating
Add to PsychonautWiki Journal
The PsychonautWiki Journal logging app doesn't include every substance. To track 5-IAI there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:
⬇ Download import file
Import this file as custom substances
and you get "5-IAI (Substance Search)" with every
route's full dose ladder and timeline, no typing. Works on iOS and
Android (v15+); the format is confirmed by the app's
developer. The manual values below work for older
versions.
Name
5-IAI
Unit
mg
Description
5-IAI Source: SubstanceSearch (substancesearch.com) Oral dose (mg): light 15-30 · common 30-50 · strong 50-100 · heavy 100+ Insufflated dose (mg): light 5-15 · common 15-35 · strong 35-60 · heavy 60+ Rectal dose (mg): threshold 30 Oral duration: onset 20-45m · come-up 0.5-1h · peak 1-3h · offset 2-3h · total 3.83-7.75h · after-effects 1-24h Insufflated duration: onset 5-15m · come-up 15-30m · peak 1-2.5h · offset 2-3h · total 3.33-6.25h · after-effects 1-24h Rectal duration: onset 10-20m · come-up 20-40m · peak 1-2.5h · offset 2-3h · total 3.5-6.5h · after-effects 1-24h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 40 mg (Oral).
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
Tolerance
Build-up
develops rapidly after a single use
Reset
7–14 days for baseline
Tolerance Decay
Full tolerance
6h
Half tolerance
14d
Baseline
~35d
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Pattern extrapolated from MDMA‑like releasers and aminoindane reports: acute tachyphylaxis within a session, partial tolerance over 1–2 weeks, and return to near‑baseline by ~4–6 weeks with abstinence. Data quality low due to absence of controlled human studies.
Cross-Tolerances
Effects
Positive
- Stimulation
- Increased energy/alertness
Negative
- Teeth grinding
- Pupil dilation
- Increased perspiration
- Weight loss
- Sweating
- Decreased need for sleep
- Decreased appetite
- Distrubed sleep patterns
- Bruxia
Positive
- Empathy and sociability
- Emotion enhancement
- Cognitive enhancement
- Euphoria
- Increased sociability
- Mood lift
Negative
- Dysphoria
- Anxiety
- Agressiveness
- Talkativeness
- Excessive talking
- Moodiness
Positive
- Tactile enhancement
- Music enhancement
- Visual enhancement
- Increased music appreciation
Negative
- Appetite suppression
- Dehydration
- Light sensitivity
- Increase sexuality
- Visual and audiotory hallucinations itchiness
- Increased sexuality
Combinations
Cross-Check 5-IAI with another substanceCommunity Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.
Bluelight 6 threads 6 neutral visit
5-IAI - Inexperienced - Odd but Interesting Prologue: Really, this substance i found to be strange. I guess i should start with the source. I got some of the last supplies. They mentioned it wasn't worth the cost of manufacture due to quantity required for research. So i obtained 1 gram before it was too late.
5IAI - research chemical claiming to have similar effects to MDMA, and release serotonin/dopamine Cheap chemical, heard mixed reviews on it. some liked it, some disliked it. Most agreed it is nowhere near as good as molly Ok, so swim recently ordered a gram of a research chemical 5IAI from an online vendor.
that's what it says on the packet. I'll update this every 30-60 mins. 5.30 pm. on a 0.00 scale I measured 25mg and bombed it. 6.05 - some slight feeling, slightly wider eyed, pretty relaxed. There is something, But almost nothing really. weighed out another 25mg bombed. I hope this is not some crap like dimethocaine.
After reading reports on here and not finding much i thought i'd post my own. I received 1g today and tried it for first time about an hour ago. The stuff i have is a fine white powder which looks like it has little crystals, it has no smell but the taste is quite horrible on the tongue.
Male, 50 yrs old,weight 80 kgs. Five years IV amphetamine use,ending about ten years ago. One years (mild) Heroin addiction ending two years ago-no maintenance. Since then I have limited myself to occasional use of RC's(well,ok, about once a week!).Didn't really rate 4-MMC, hated bk-MBDB,enjoyed MDPV, loved Methylone-e...
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