5-MAPDB
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 3 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 18 combo interactions documented
- classified Research-chemical
- 3 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 18 combo interactions documented
- classified Research-chemical
Aliases: 5mapdb
Summary
5-MAPDB is a dihydrobenzofuran entactogen first characterized by Monte et al. (1993) and pharmacologically profiled by Rickli et al. (2015).
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 50-75mg | 75-120mg | 120-150mg | 150mg+ |
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 45-70 min | 30-60 min | 2-4 hrs | 1-2 hrs | 5-8 hrs |
| Insufflated | 5-15 min | 15-30 min | 2-4 hrs | 1-2 hrs | 5-8 hrs |
| Rectal | 5-15 min | 15-30 min | 2-4 hrs | 1-2 hrs | 5-8 hrs |
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Mild auditory effects and body load with low visuals
Strong sensory enhancement with moderate empathy, mild euphoria, low stimulation
Moderate anxiety/jitters with mild euphoria, low stimulation
Add to PsychonautWiki Journal
The PsychonautWiki Journal logging app doesn't include every substance. To track 5-MAPDB there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:
5-MAPDB Source: SubstanceSearch (substancesearch.com) Oral dose (mg): light 50-75 · common 75-120 · strong 120-150 · heavy 150+ Insufflated dose (mg): threshold 5 Rectal dose (mg): threshold 15 Oral duration: onset 0.75-1.17h · come-up 0.5-1h · peak 2-4h · offset 1-2h · total 5-8h · after-effects 2-4h Insufflated duration: onset 5-15m · come-up 15-30m · peak 2-4h · offset 1-2h · total 5-8h · after-effects 2-4h Rectal duration: onset 5-15m · come-up 15-30m · peak 2-4h · offset 1-2h · total 5-8h · after-effects 2-4h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 97.5 mg (Oral).
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
- Stimulation
- Increased energy/alertness
- Pupil dilation
- Bruxism
- Jaw clenching
- Sweating
- Insomnia during comedown
- Weight loss
- Difficulty urinating
- Reduced appetite
- Decreased need for sleep
- Decreased appetite
- Distrubed sleep patterns
- Bruxia
- Euphoria
- Empathy
- Emotional openness
- Increased sociability
- Enhanced music appreciation
- Mood lift
- Next-day lethargy or low mood
- Agressiveness
- Excessive talking
- Moodiness
- Enhanced tactile sensation
- Mild visual enhancement
- Tactile enhancement
- Increased music appreciation
- Bodily control enhancement
- Increased libido
- Tracers
- Light sensitivity
- Increase sexuality
- Visual and audiotory hallucinations itchiness
Combinations
Cross-Check 5-MAPDB with another substanceHelpful Links
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