5-MeO-MiPT - Substance Search

Summary TheDrug.Wiki Erowid TripSit PsychonautWiki

5-Methoxy-N-methyl-N-isopropyltryptamine (also known as 5-MeO-MiPT and moxy) is a lesser-known psychedelic substance of the tryptamine class. 5-MeO-MiPT is chemically related to tryptamines like 5-MeO-DMT and 5-MeO-DiPT. It produces its psychoactive effects through activity at serotonin receptors in the brain.

Perspectives

“This would be my first foray into the 5-MeO-Tryptamines and I would later come to understand them as their own class of drug entirely. They do not follow the patterns of traditional psychedelic visual effects—rather they are vague, disconnected, and extremely abstract. The headspace is unlike anything else, it’s a blank neutrality.”

— Nervewing, nervewing.blogspot.com

“In 15 minutes I was already off of baseline, and by an hour it is unquestionably real. There is no visualization to music, but a general turned-on randiness. Dropping at an hour and a half, and out by three hours. Modest but real.”

— Alexander Shulgin, TiHKAL (with 1.5 mg, orally)

Dose Information TheDrug.Wiki TripSit PsychonautWiki

ROA	Light	Common	Strong	Heavy
Oral	3-7mg	7-15mg	15-20mg	20mg+
Sublingual	3-7mg	7-15mg	15-20mg	20mg+
Smoked	5-10mg	10-15mg	15-20mg	20mg+

Light Common Strong Heavy

Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

ROA	Onset	Comeup	Peak	Offset	After Effects	Total
Oral	19-40 min	30-60 min	2-3 hrs	2-3 hrs	2-4 hrs	5-8 hrs
Sublingual	19-60 min	30-60 min	1-2 hrs	1-2 hrs	1-3 hrs	3-7 hrs
Smoked	19-60 min	1-4 min	15-30 min	1-2 hrs	1-2 hrs	5-8 hrs

Effect Profile

133 reports

Scores (1–10) curated from multiple sources:

Effect keyword matching from PsychonautWiki catalog
Validated against 105 Erowid trip reports
Weighted by importance: core (×3), major (×2), minor (×1)

Full methodology

Psychedelic 8.8

Intense+ 9/10

Strong visuals, headspace, auditory effects, and body load

Visual Intensity ×3

10

internal hallucinations colour enhancement autonomous entities drifting tracers colour shifting +6 more

Headspace Depth ×3

10

conceptual thinking thought connectivity emotion enhancement perspective alterations personal bias suppression time distortion +1 more

Auditory Effects ×1

10

auditory distortion auditory enhancement auditory hallucinations auditory hallucination

⚠ Body Load / Somatic Effects ×1

10

nausea vasoconstriction muscle tension bodily pressures increased heart rate

Empathogen 10.0

Extreme 10/10

Strong empathy, euphoria, stimulation, and sensory enhancement

Empathy / Social Openness ×3

10

empathy enhancement empathy empathy, love, and sociability enhancement empathy, affection and sociability enhancement

Euphoria / Mood Elevation ×2

10

euphoria emotion enhancement

Stimulation ×1

10

stimulation wakefulness restlessness increased heart rate

Sensory Enhancement ×1

10

tactile enhancement enhanced tactile sensation spontaneous tactile sensations colour enhancement acuity enhancement visual acuity enhancement +1 more

Based on reports from:

Effect Index The Stillness and the Fluttering TiHKAL TiHKAL #40: 5-MeO-MIPT Bluelight Big & Dandy Thread Erowid Experience Reports PsychonautWiki 5-MeO-MiPT

Tolerance

Build-up develops rapidly after a single use

Reset 7–14 days for baseline

Tolerance Decay

Full tolerance 0h Half tolerance 3d Baseline ~5d

Based on Erowid’s basics page indicating a short tolerance window with near‑baseline by 5–7+ days; quantitative values are heuristic for planning gaps, not pharmacokinetic measurements. Cross‑tolerance pattern inferred from general psychedelic class behavior (TripSit).

Cross-Tolerances

LSD/psilocybin/other serotonergic psychedelics

50%

Effects Erowid Bluelight

Aggregated from 105 Erowid and 28 Bluelight experience reports

Positive Effects 62

Stimulation 51.9% 84%

Euphoria 51.9% 88%

Music Enhancement 51.9% 88%

Color Enhancement 45.8% 85%

Tactile Enhancement 45.1% 86%

Focus Enhancement 38.1% 70%

Libido Enhancement 32.1% 84%

Introspection 31.6% 80%

Body High 30.8% 90%

Closed-Eye Visuals 30.8% 86%

Geometric Imagery 28.6% 86%

Joy 28.6% 84%

Analysis Enhancement 28.6% 81%

Empathy 28.5% 87%

Auditory Effects 27.1% 81%

Sedation 26.3% 80%

Sociability Enhancement 25.0% 82%

Melting/flowing 21.4% 85%

Patterning 21.4% 85%

Morphing 21.4% 86%

Adverse Effects 46

Anxiety 41.4% 79%

Body Load 35.7% 82%

Nausea 34.6% 84%

Muscle Tension 32.3% 80%

Confusion 22.5% 80%

Fear 17.9% 83%

Increased Heart Rate 16.2% 70%

Social Anxiety 14.3% 79%

Thought Disorganization 14.3% 79%

Libido Suppression 10.7% 77%

Paranoia 10.7% 82%

Restlessness 10.7% 80%

Memory Suppression 10.5% 80%

Sweating 7.6% 70%

Heaviness 7.1% 78%

Stomach Cramps 7.1% 65%

Delusion 7.1% 80%

Emotional Lability 7.1% 80%

Pareidolia 7.1% 88%

Insomnia 7.1% 75%

Combinations TripSit

Trip Reports Effect Index

The Stillness and the Fluttering nervewing

PiHKAL / TiHKAL Shulgin

TiHKAL #40: 5-MeO-MIPT

“In 15 minutes I was already off of baseline, and by an hour it is unquestionably real. There is no visualization to music, but a general turned-on randiness. Dropping at an hour and a half, and out by three hours. Modest but real.”

— Alexander Shulgin, TiHKAL (with 1.5 mg, orally)

5-MeO-MiPT's nerd page Pharmacology, chemical data, effect profiles, and more

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Helpful Links

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