5F-PB-22
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 3 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 16 combo interactions documented
- PubChem toxicity data
- classified Tentative
- classified Research-chemical
- 3 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 16 combo interactions documented
- PubChem toxicity data
- classified Tentative
- classified Research-chemical
Summary
5F-PB-22 (1-pentyfluoro-1H-indole-3-carboxylic acid 8-quinolinyl ester also known as 5F-QUPIC) is a synthetic cannabinoid and agonist of the cannabinoid receptors which produces predominantly sedating subjective effects somewhat similar to that of cannabis. There is very little information regarding the pharmacology of this compound within the scientific literature. Despite this, however, it has been sold as a grey area research chemical through online vendors.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 1-3mg | 3-5mg | 5-8mg | 8mg+ |
| Smoked | 1-3mg | 3-5mg | 5-8mg | 8mg+ |
Onset, Duration & After-effects
| ROA | Onset | Peak | Offset | Total |
|---|---|---|---|---|
| Oral | 5-10 min | 60-90 min | 60 min | 2-3 hrs |
| Smoked | - | 30 min | 60 min | 90 min |
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
- Pain relief
- Stimulation
- Increased heart rate
- Insomnia
- Pupil dilation
- Nausea
- Spontaneous bodily sensations
- Vasodilation
- Sedation
- Decreased appetite
- Thought connectivity
- Mindfulness
- Conceptual thinking
- Cognitive euphoria
- Immersion intensification
- Anxiety
- Paranoia
- Thought deceleration
- Dream suppression
- Motor control loss
- Psychosis
- Emotion intensification
- Color enhancement
- Increased music appreciation
- Auditory acuity enhancement
- Dehydration
- Visual acuity suppression
- Light sensitivity
- Changes in felt gravity
- Perception of bodily heaviness
- Appetite intensification
- Dulled perception
Combinations
Cross-Check 5F-PB-22 with another substanceHelpful Links
Report an issue or suggest an edit
Spotted incorrect or dangerous information, have a correction, a new study, or a useful addition for 5F-PB-22? Let us know. Reports are reviewed by moderators — this is not posted publicly.