Summary
6-APDB was designed as a potentially less neurotoxic alternative to MDMA but may still pose neurotoxic and cardiotoxic risks with repeated or high-dose use. CRITICAL WARNING: As a potent serotonin releaser, 6-APDB carries serious risk of potentially fatal serotonin syndrome when combined with antidepressants, MAOIs, or other serotonergic drugs. The substance causes significant hyperthermia which can be life-threatening; users must monitor body temperature and stay properly hydrated. Individuals with personal or family histories of heart conditions should avoid use. Use accurate milligram scales for dosing, as the therapeutic window is narrow and overdose can be dangerous.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 30-70mg | 70-100mg | 100-130mg | 130mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | After Effects | Total |
|---|---|---|---|---|---|---|
| Oral | 30-60 min | 30-60 min | 2.0-3.0 hrs | 2.0-3.0 hrs | 24.0 hrs | 7.0-9.0 hrs |
Tolerance
Build-up
develops over days to weeks of regular use
Reset
3–7 days for acute; 1–3 weeks for full reset
Effects
Positive
- Physical euphoria
- Stamina enhancement
- Creativity enhancement
- Increased energy/alertness
- Stimulation
Negative
- Pupil dilation
- Increased heart rate
- Increased blood pressure
- Increased perspiration
- Teeth grinding
- Nystagmus
- Temporary erectile dysfunction
- Weight loss
- Sweating
- Stimulation and sedation
- Increased bodily temperature
- Difficulty urinating
- Decreased need for sleep
- Decreased appetite
- Distrubed sleep patterns
- Bruxia
- Spontaneous bodily sensations
- Sedation
- Stamina intensification
Positive
- Empathy, love, and sociability enhancement
- Cognitive euphoria
- Anxiety suppression
- Focus enhancement
- Immersion enhancement
- Mindfulness
- Motivation enhancement
- Wakefulness
- Unity and interconnectedness
- Euphoria
- Increased sociability
- Mood lift
- Empathy, affection and sociability enhancement
- Dream potentiation
- Immersion intensification
Negative
- Compulsive redosing
- Agressiveness
- Depression
- Anxiety
- Irritability
- Thought deceleration
- Brain zaps
- Cognitive fatigue
- Motivation depression
- Time distortion
- Thought acceleration
- Peripheral information misinterpretation
- Excessive talking
- Moodiness
- Existential self-realization
- Focus intensification
Positive
- Increased music appreciation
- Tactile enhancement
- Bodily control enhancement
- Perception of bodily lightness
- Increased libido
- Auditory enhancement
- Colour enhancement
- Pattern recognition enhancement
- Acuity enhancement
- Tracers
- Color enhancement
- Auditory acuity enhancement
Negative
- Dehydration
- Appetite suppression
- After images
- Autonomous entities
- Increase sexuality
- Visual and audiotory hallucinations itchiness
- Auditory hallucination
- Auditory distortion
- Vibrating vision
- Symmetrical texture repetition
- External hallucination
- Internal hallucination
- Autonomous entity
- Perspective hallucination
- Tactile intensification