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    ๐Ÿงช This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    6-APDB Well-documented
    Well-documented
    Multiple authoritative sources agree on dosing and effects.
    • 6 corroborating sources
    • 1 ROA with full dose ladder
    • duration data present
    • 20 combo interactions documented
    • PubChem toxicity data
    • classified Research-chemical

    Aliases: Ema-3, 4-desoxy-mda

    Summary TheDrug.Wiki TripSit PsychonautWiki

    6-APDB (also known as 6-(2-aminopropyl)-2,3-dihydrobenzofuran or 4-Desoxy-MDA) is a stimulant and entactogenic research chemical of the phenethylamine and benzofuran classes. It is a closely related synthetic analogue of MDA and 6-APB and broadly shares the characteristics of serotonin-selective triple monoamine releasers and reuptake inhibitors associated with other entactogenic or empathogenic compounds. 6-APDB was first synthesized and studied along with 5-APDB in 1993 by David E.

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 30-70mg 70-100mg 100-130mg 130mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 30-60 min 30-60 min 2-3 hrs 2-3 hrs 24 hrs 7-9 hrs

    Effect Profile

    2 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 6.1
    Strong 6/10

    Strong visuals and auditory effects with mild body load, low headspace

    Visual Intensity ×3
    10
    colour enhancement autonomous entities tracers pattern recognition enhancement after images acuity enhancement
    Headspace Depth ×3
    1
    time distortion
    Auditory Effects ×1
    10
    auditory enhancement auditory distortion auditory hallucination
    Body Load / Somatic Effects ×1
    4
    teeth grinding increased heart rate sweating
    Empathogen 8.7
    Intense+ 9/10

    Strong euphoria, sensory enhancement, and empathy with moderate stimulation

    Empathy / Social Openness ×3
    8
    empathy, love, and sociability enhancement empathy, affection and sociability enhancement increased sociability
    Euphoria / Mood Elevation ×2
    10
    physical euphoria cognitive euphoria euphoria mood lift
    Stimulation ×1
    7
    stimulation wakefulness teeth grinding increased heart rate
    Sensory Enhancement ×1
    10
    tactile enhancement colour enhancement acuity enhancement increased libido
    Stimulant 7.0
    Strong+ 7/10

    Strong euphoria and anxiety/jitters with moderate stimulation and focus

    Stimulation / Energy ×3
    7
    stimulation stamina enhancement wakefulness
    Euphoria / Mood Lift ×2
    10
    physical euphoria cognitive euphoria euphoria mood lift motivation enhancement
    Focus / Productivity ×2
    7
    focus enhancement motivation enhancement thought acceleration
    Anxiety / Jitters ×1
    9
    anxiety increased heart rate teeth grinding sweating

    Tolerance

    Build-up develops over days to weeks of regular use
    Reset 3โ€“7 days for acute; 1โ€“3 weeks for full reset

    Tolerance Decay

    Full tolerance 1d Half tolerance 30d Baseline ~90d

    Effects TheDrug.Wiki TripSit PsychonautWiki

    Positive
    • Physical euphoria
    • Stamina enhancement
    • Creativity enhancement
    • Increased energy/alertness
    • Stimulation
    Negative
    • Pupil dilation
    • Increased heart rate
    • Increased blood pressure
    • Increased perspiration
    • Teeth grinding
    • Nystagmus
    • Temporary erectile dysfunction
    • Weight loss
    • Sweating
    Neutral
    • Stimulation and sedation
    • Increased bodily temperature
    • Difficulty urinating
    • Decreased need for sleep
    • Decreased appetite
    • Distrubed sleep patterns
    • Bruxia
    • Spontaneous bodily sensations
    • Sedation
    • Stamina intensification
    Positive
    • Empathy, love, and sociability enhancement
    • Cognitive euphoria
    • Anxiety suppression
    • Focus enhancement
    • Immersion enhancement
    • Mindfulness
    • Motivation enhancement
    • Wakefulness
    • Unity and interconnectedness
    • Euphoria
    • Increased sociability
    • Mood lift
    • Empathy, affection and sociability enhancement
    • Dream potentiation
    • Immersion intensification
    Negative
    • Compulsive redosing
    • Agressiveness
    • Depression
    • Anxiety
    • Irritability
    • Thought deceleration
    • Brain zaps
    • Cognitive fatigue
    • Motivation depression
    Neutral
    • Time distortion
    • Thought acceleration
    • Peripheral information misinterpretation
    • Excessive talking
    • Moodiness
    • Existential self-realization
    • Focus intensification
    Positive
    • Increased music appreciation
    • Tactile enhancement
    • Bodily control enhancement
    • Perception of bodily lightness
    • Increased libido
    • Auditory enhancement
    • Colour enhancement
    • Pattern recognition enhancement
    • Acuity enhancement
    • Tracers
    • Color enhancement
    • Auditory acuity enhancement
    Negative
    • Dehydration
    • Appetite suppression
    Neutral
    • After images
    • Autonomous entities
    • Increase sexuality
    • Visual and audiotory hallucinations itchiness
    • Auditory hallucination
    • Auditory distortion
    • Vibrating vision
    • Symmetrical texture repetition
    • External hallucination
    • Internal hallucination
    • Autonomous entity
    • Perspective hallucination
    • Tactile intensification

    Combinations TripSit

    Cross-Check 6-APDB with another substance

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.

    Erowid 2 reports 2 neutral visit
    Long Neutral Entactogenesis neutral exp #105428

    Me: 63kg white male. 30 years old. Generally, my reactions to psychoactives are idiosyncratic; for instance, I loathe cannabis and MDMA makes me feel sad and antisocial. So take this report with a grain of salt-your mileage may vary.

    Pfaffed · 45 mg oral / 20 mg oral / repeated oral
    Qu'est-ce que c'est? neutral exp #102135

    First some notes on a prior experiences and then some notes on a particular experience, si? A chemist friend graciously tested the material by NMR and ESI-MS and found it to be an inorganic salt of 6-APDB. Prior experiences at 80 mg yielded clear ++ experiences without a strong independent character.

    slownerveaction · 100 mg oral
    Bluelight 2 threads 2 neutral visit
    6 Apdb 65mg First Time Long Neutral Entactogenesis neutral

    Me: 63kg white male. 30 years old. Generally, my reactions to psychoactives are idiosyncratic; for instance, I loathe cannabis and MDMA makes me feel sad and antisocial. So take this report with a grain of salt--your mileage may vary.

    scraped 2026-03-14
    6 Apdb 60mg Strong Come Up Mild Ride neutral

    The powder I have is off-white/light-tan. I started this thread, posting my marquis, mecke, mandelin, simon`s and robadope tests to try to sort it out and see if someone had anything similar (thanks everyone for helping me out!), however the results were still not very clear.

    scraped 2026-03-14

    Bluelight Reference Guide Bluelight

    The Main 6-APDB Thread

    hi there, it seems like 6-APDB is available now and will become even more widely available in the near future. i'll receive a sample of this compound soon and i'm wondering if anyone has already sampled it and how it compares to 6-ABP.

    Read full thread on Bluelight โ†’

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