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    ๐Ÿงช This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    a-PVP

    Aliases: Flakka, Gravel, Flocka, O-2387, Alpha-pyrrolidinopentiophenone, alpha-pvp, apvp, ฮฑ-pvp, ฮฑpvp

    Stimulant Research-chemical

    Summary TheDrug.Wiki Erowid TripSit PsychonautWiki

    alpha-PVP is an extremely potent synthetic stimulant with a very short history of human use and minimal safety data. It is notorious for inducing powerful compulsive redosing, severe paranoia, psychosis, and excited delirium at high doses or during binges. Vaporized administration carries especially high overdose risk due to rapid onset.

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 5-10mg 10-25mg 25-40mg 40mg+
    Insufflated 1-5mg 5-15mg 15-25mg 25mg+
    Vaporized 2-5mg 5-15mg 15-25mg 25mg+
    Smoked 2-5mg 5-15mg 15-25mg 25mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 5-30 min 30-60 min 1-2.5 hrs 1-5 hrs 4-12 hrs 2.6-9 hrs
    Insufflated 1-5 min 5-15 min 20-45 min 30-90 min 2-4 hrs 0.9-2.6 hrs

    Effect Profile

    11 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Stimulant 6.4
    Strong 6/10

    Strong anxiety/jitters, euphoria, and focus with mild stimulation

    Stimulation / Energy ×3
    5
    stimulation wakefulness
    Euphoria / Mood Lift ×2
    9
    euphoria cognitive euphoria mood lift motivation enhancement
    Focus / Productivity ×2
    9
    focus enhancement analysis enhancement motivation enhancement thought acceleration
    ⚠ Anxiety / Jitters ×1
    10
    anxiety paranoia increased heart rate teeth grinding vasoconstriction sweating
    Based on reports from:
    Erowid Experience Reports PsychonautWiki a-PVP
    View methodology →

    Tolerance

    Build-up develops rapidly with compulsive redosing
    Reset a few days for acute effects

    Tolerance Decay

    Full tolerance 2d Half tolerance 4d Baseline ~14d

    Rapid tolerance buildup within/between sessions is widely reported for pyrrolidinophenones; decay back toward baseline likely occurs over 1โ€“2 weeks of abstinence. Values are heuristic, based on stimulant tolerance patterns and user reports; high uncertainty.

    Cross-Tolerances

    Other cathinones (e.g., MDPV, ฮฑโ€‘PHP, NEP)
    60%
    Common stimulants (amphetamine, cocaine)
    30%

    Effects Erowid

    Aggregated from 11 Erowid experience reports

    Positive Effects 6

    Euphoria 81.8% 70%
    Stimulation 54.5% 70%
    Focus Enhancement 45.5% 70%
    Empathy 45.5% 70%
    Pain Relief 27.3% 70%
    Tactile Enhancement 27.3% 70%

    Adverse Effects 3

    Anxiety 72.7% 70%
    Increased Heart Rate 63.6% 70%
    Psychosis 27.3% 70%

    Combinations TripSit

    a-PVP's nerd page Pharmacology, chemical data, effect profiles, and more
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    Helpful Links

    ๐Ÿ“˜ Experience Reports ๐Ÿ“– TheDrug.Wiki ๐Ÿ“– PsychonautWiki ๐Ÿ“– TripSit