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    Disclaimer
    ☠ This is an extremely potent opioid active in microgram doses. Accidental overdose can be rapidly fatal. Naloxone should always be on hand.
    πŸ§ͺ This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    Acetylfentanyl Well-documented
    Well-documented
    Multiple authoritative sources agree on dosing and effects.
    • 6 corroborating sources
    • 3 ROAs with full dose ladders
    • duration data present
    • 19 combo interactions documented
    • PubChem toxicity data
    • classified Research-chemical

    Aliases: A-f, Desmethyl fentanyl, Wrongly called china white, acetyl-fentanyl

    Summary TheDrug.Wiki Erowid TripSit PsychonautWiki

    Acetylfentanyl is a synthetic opioid substance of the anilidopiperidine chemical class that produces analgesic, anxiety suppressing, and euphoric effects when administered. It is a structural analog of fentanyl. Studies have estimated acetylfentanyl to be between five to fifteen times more potent than heroin, eighty times more potent than morphine, and fifteen times less potent than its parent compound, fentanyl.

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Sublingual 5-10mg 10-15mg 15-20mg 20mg+
    Insufflated 5-10mg 10-15mg 15-20mg 20mg+
    Oral 1-3mg 3-5mg 5-7mg 7mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Peak Offset After Effects Total
    Sublingual 20-40 min 1-2 hrs 30-90 min 1-4 hrs 1-4 hrs
    Insufflated 5-15 min 30-90 min 30-60 min 1-3 hrs 1-4 hrs
    Oral 5-20 min 1-4 hrs - 1-8 hrs 1-4 hrs

    Effect Profile

    5 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Opioid 8.4
    Intense 8/10

    Strong euphoria and pain relief with moderate sedation, mild itching/nausea

    Euphoria / Warmth ×3
    10
    physical euphoria cognitive euphoria euphoria mood lift
    Analgesia ×2
    8
    pain relief analgesia
    Sedation / Relaxation ×1
    7
    sedation drowsiness dream potentiation
    Itching / Nausea ×1
    4
    constipation dry mouth

    Tolerance

    Build-up develops within days of regular use; analgesic tolerance faster than respiratory depression tolerance
    Reset 7–14 days for partial reset; full reset may take weeks β€” tolerance loss greatly increases overdose risk

    Tolerance Decay

    Full tolerance 1d Half tolerance 21d Baseline ~35d

    Effects TheDrug.Wiki TripSit PsychonautWiki

    Positive
    • Pain Relief
    • Physical Euphoria
    • Cough Suppression
    • Analgesia
    Negative
    • Respiratory Depression
    • Dry Mouth
    Neutral
    • Sedation
    • Itchiness
    • Pupil Constriction
    • Difficulty Urinating
    • Relaxant
    Positive
    • Cognitive Euphoria
    • Anxiety Suppression
    • Dream Potentiation
    • Euphoria
    • Mood lift
    • Feelings of relaxation
    Negative
    • Constipation
    • Compulsive Redosing
    • Drowsiness
    Neutral
    • Changes in focus
    Negative
    • Decreased Libido
    • Dehydration
    • Double Vision
    • Appetite Suppression
    • Orgasm Suppression
    • Orgasm depression
    • Acuity Suppression
    • Disinhibition
    • Light sensitivity
    Neutral
    • Dulled perception

    Combinations TripSit

    Cross-Check Acetylfentanyl with another substance

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.

    Erowid 4 reports 3 neutral 1 cautionary visit
    First Time Out neutral exp #106838

    Dose 12 mg Acetyl Fentanyl IM'ed Preparation - I mixed 12 mg (0.012 g) Acetyl Fentanyl with 50 units (0.5 mL) of water. I drew up less than 50 units of fluid into the rig through cotton. Next I ejected the rig down to 40 units of fluid for ease of measurement.

    TaUrz
    100% Pain Relief neutral exp #102018

    AcetylFentanyl - word was this was a research chemical with properties similar to Heroin or Morphine. In fact, it is touted as stronger than both. I bought a full gram (enough to put down ten 200 lb people for good, so be careful with the dosage). Stuff is extremely cheap.

    Matty · 10 mg sublingual
    Not Impressed neutral exp #107574

    Hey. I'm just a 20 year old college kid who's dabbled in drugs quite a bit. I'm up in Canada and fentanyl is making its rounds around here. I managed to get some candies dipped in 5mg Acetyl Fentanyl. Perhaps they were bunk or not really 5mg but I kept redosing and couldn't get any euphoria from these.

    Drewpy · oral
    I Realized I Was Becoming Addicted cautionary exp #107307

    I started taking acetyl fentanyl blotters that I bought off the dark net for two months solid. ThatΒ’s one of the hardest withdrawals youΒ’ll ever know in life. ItΒ’s worse than dilaudid, worse than oxy, worse than hydrocodone, itΒ’s 50-100 times stronger than heroin but still 15 times less than fentanyl.

    Eyeamffd · repeated

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