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    Disclaimer
    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.
    ⚠ Synthetic cannabinoids are far more potent and unpredictable than natural cannabis. They lack a ceiling effect and have been linked to seizures, psychosis, and death.

    ADB-INACA Encyclopedic
    Encyclopedic
    Typical encyclopedia coverage. Cross-reference for important decisions.
    • 2 corroborating sources
    • 2 ROAs with full dose ladders
    • duration data present
    • 16 combo interactions documented
    • classified Research-chemical
    • dose data not in PW/TripSit (unverifiable)

    Research-chemical Cannabinoid

    Summary dose.wiki

    ADB-INACA is an indazole-3-carboxamide frequently detected as a precursor or minor component alongside potent synthetic cannabinoids in seized products; real-world harms often reflect co-formulation with more active compounds rather than pure ADB-INACA effects. As a suspected precursor to compounds like ADB-BUTINACA, overall potency is expected to be low, though pharmacological data remain limited. Treat unknown powders and sprayed materials as if they contain nanomolar CB1 agonists; never eyeball doses, use a milligram scale or volumetric solutions, start at sub-milligram smoked or low-milligram oral doses, and wait through the full peak before redosing.

    Dose Information dose.wiki Drugs.Wiki

    Dose basis. Ranges are based on sparse, mixed user reports for potent indazole/indole carboxamide SCRAs rather than ADB-INACA-specific trials; extreme inter-batch variability and frequent mislabeling mean these values are at best rough starting bounds. Avoid eyeballing; use a 0.001 g scale or volumetric dosing and wait a full peak before redosing. Erowid and clinical reviews highlight that SCRA products have become increasingly dangerous and are not reliably identified without MS-based testing. SCRA-laced plant/papers can have uneven ‘hot spots’ and potency that differs by orders of magnitude; inhalation enables rapid overdose. Take a single, very small test puff from thoroughly homogenized, very dilute material, then wait ≥15–30 minutes. Do not chase effects with repeated quick puffs. (Dose figures and this note are from Drugs.Wiki.)

    ROA Light Common Strong Heavy
    Oral 1-3mg 3-6mg 6-10mg 10mg+
    Smoked 0.5-1mg 1-3mg 3-5mg 5mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects dose.wiki Drugs.Wiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 15-45 min 15-30 min 30-90 min 1-2 hrs 1-3 hrs 2-4.75 hrs
    Smoked 36 sec 2-5 min 15-45 min 30-60 min 1-3 hrs 0.79-1.84 hrs

    Add to PsychonautWiki Journal

    The PsychonautWiki Journal logging app doesn't include every substance. To track ADB-INACA there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:

    ⬇ Download import file Import this file as custom substances and you get "ADB-INACA (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer. The manual values below work for older versions.
    Name
    ADB-INACA
    Unit
    mg
    Description 
    ADB-INACA
Source: SubstanceSearch (substancesearch.com)

Oral dose (mg): threshold 1 · light 1-3 · common 3-6 · strong 6-10 · heavy 10+
Smoked dose (mg): threshold 0.5 · light 0.5-1 · common 1-3 · strong 3-5 · heavy 5+

Oral duration: onset 15-45m · come-up 15-30m · peak 0.5-1.5h · offset 1-2h · total 2-4.75h · after-effects 1-3h
Smoked duration: onset 36s · come-up 2-5m · peak 15-45m · offset 0.5-1h · total 0.79-1.84h · after-effects 1-3h

Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 4.5 mg (Oral).

    The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.

    Tolerance

    Build-up develops over weeks of regular use via CB1 receptor downregulation
    Reset 2–4 weeks for most users; heavy users may need longer

    Tolerance Decay

    Full tolerance 3d Half tolerance 14d Baseline ~28d

    Rapid tolerance build with repeated/daily use is commonly reported for SCRA class; decay appears slower than build and incomplete for weeks. Data quality is low and largely anecdotal across varying compounds/products.

    Cross-Tolerances

    THC/cannabis
    30%
    Other SCRAs
    70%

    Effects dose.wiki

    Positive
    • Pain relief
    • Physical euphoria
    Negative
    • Dry mouth
    • Increased heart rate
    • Nausea
    • Tachycardia
    • Tachycardia and palpitations
    Neutral
    • Sedation
    • Spontaneous bodily sensations
    • Vasodilation
    Positive
    • Euphoria
    • Thought connectivity
    Negative
    • Anxiety
    • Paranoia
    • Motor control loss
    • Dizziness
    • Confusion
    • Short-term memory suppression
    • Psychosis
    Neutral
    • Time distortion
    Positive
    • Appetite enhancement
    • Color enhancement
    • Perception of bodily lightness
    • Increased Music Appreciation
    • Bodily control enhancement
    Negative
    • Dehydration
    Neutral
    • Visual distortions
    • Appetite intensification
    • Changes in felt gravity
    • Closed-eye imagery

    Combinations

    Cross-Check ADB-INACA with another substance

    ADB-INACA's nerd page Pharmacology, chemical data, effect profiles, and more
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    Helpful Links

    📘 Experience Reports 📖 dose.wiki 📖 PsychonautWiki