Summary
ADBICA is a highly potent full agonist at CB1 and CB2 receptors, significantly stronger than delta-9-THC. Because batches are often mis-weighed or sprayed unevenly on herbal material, accidental overdose is common and has been linked to acute psychosis, seizures, tachyarrhythmia, kidney injury and death. Begin with micro-doses carefully weighed on a 0.001 g scale. Avoid redosing within the same session; effects can spike suddenly. Provide a calm setting, hydration and a sober sitter.
Dose Information
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Peak | Offset | After Effects |
|---|---|---|---|---|
| Smoked | 1-2 min | 5-30 min | 60 min | 1-3 hrs |
| Oral | 30-60 min | 1-3 hrs | 2 hrs | 1-3 hrs |
Tolerance
Build-up
develops over weeks of regular use via CB1 receptor downregulation
Reset
2–4 weeks for most users; heavy users may need longer
Effects
Positive
- Pain relief
- Stimulation
Negative
- Dry mouth
- Tachycardia
- Nausea/vomiting
- Strong dysphoria on comedown
- Nausea
- Red eyes
- Spontaneous bodily sensations
- Vasodilation
Positive
- Euphoria
- Thought connectivity
- Mindfulness
- Conceptual thinking
Negative
- Anxiety
- Paranoia
- Rapid, intense intoxication
- Anxiolysis or severe anxiety/panic
- Time distortion
- Dissociation at high doses
Positive
- Increased music appreciation
- Auditory acuity enhancement
Negative
- Dehydration
- Visual sharpening or mild pseudo-hallucinations
- Dulled perception
- Auditory distortion
- Changes in felt gravity
- Perception of bodily heaviness
- Appetite intensification
- Drifting