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    Disclaimer
    πŸ§ͺ This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.
    ⚠ Synthetic cannabinoids are far more potent and unpredictable than natural cannabis. They lack a ceiling effect and have been linked to seizures, psychosis, and death.

    ADBICA Encyclopedic
    Encyclopedic
    Typical encyclopedia coverage. Cross-reference for important decisions.
    • 3 corroborating sources
    • 2 ROAs with full dose ladders
    • duration data present
    • 16 combo interactions documented
    • classified Research-chemical
    • dose data not in PW/TripSit (unverifiable)

    Aliases: Adb-pica

    Summary dose.wiki

    ADBICA is a highly potent full agonist at CB1 and CB2 receptors, significantly stronger than delta-9-THC. Because batches are often mis-weighed or sprayed unevenly on herbal material, accidental overdose is common and has been linked to acute psychosis, seizures, tachyarrhythmia, kidney injury and death. Begin with micro-doses carefully weighed on a 0.001 g scale.

    Dose Information dose.wiki Drugs.Wiki

    Dose basis. Dose data for ADBICA are not from clinical trials; they come predominantly from forensic detections and community reports of similarly potent indole/indazole carboxamide SCRAs. Potency can be sub‑milligram; do not eyeball. Prefer volumetric dosing (dissolve a weighed amount in a known volume of ethanol/PG and measure by volume). Community harm-reduction discussions emphasize that cheap mg scales are unreliable under ~20 mg; use a calibrated 0.001 g scale and make a dilute solution to measure safer sub‑mg portions. Synthetic-cannabinoid blends can contain β€œhot spots” from uneven sprayingβ€”avoid home‑spraying plant material; use measured solutions instead. Citations: Erowid β€˜Spice & spin‑offs’ notes microgram‑range potency; Bluelight volumetric dosing thread; Reddit discussion on mg‑scale accuracy limits; Erowid note on variability of packaged β€˜spice’ products. Oral onset is delayed and peaks later than smoked; avoid redosing for at least 2–3 hours to prevent accidental overdose. As with smoked use, rely on volumetric dosing and an accurate scale; do not β€˜eyeball’. Citations: general dosing caution from Erowid β€˜Dose’; community volumetric dosing guidance on Bluelight. (Dose figures and this note are from Drugs.Wiki.)

    ROA Light Common Strong Heavy
    Smoked 0.25-0.5mg 0.5-1mg 1-1.5mg 1.5mg+
    Oral 0.3-0.6mg 0.6-1.2mg 1.2-2mg 2mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects dose.wiki Drugs.Wiki

    ROA Onset Peak Offset After Effects Total
    Smoked 1-2 min 5-30 min 60 min 1-3 hrs 1.09-1.53 hrs
    Oral 30-60 min 1-3 hrs 2 hrs 1-3 hrs 3.5-6 hrs

    Effect Profile

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 3.9
    Moderate 4/10

    Mild headspace, auditory effects, and body load with low visuals

    Visual Intensity ×3
    2
    drifting
    Headspace Depth ×3
    5
    conceptual thinking thought connectivity time distortion
    Auditory Effects ×1
    4
    auditory distortion
    Body Load / Somatic Effects ×1
    4
    nausea tachycardia

    Add to PsychonautWiki Journal

    The PsychonautWiki Journal logging app doesn't include every substance. To track ADBICA there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:

    ⬇ Download import file Import this file as custom substances and you get "ADBICA (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer. The manual values below work for older versions.
    Name
    ADBICA
    Unit
    mg
    Description
    ADBICA
    Source: SubstanceSearch (substancesearch.com)
    
    Smoked dose (mg): threshold 0.25 Β· light 0.25-0.5 Β· common 0.5-1 Β· strong 1-1.5 Β· heavy 1.5+
    Oral dose (mg): threshold 0.3 Β· light 0.3-0.6 Β· common 0.6-1.2 Β· strong 1.2-2 Β· heavy 2+
    
    Smoked duration: onset 1-2m Β· peak 5-30m Β· offset 1h Β· total 1.09-1.53h Β· after-effects 1-3h
    Oral duration: onset 0.5-1h Β· peak 1-3h Β· offset 2h Β· total 3.5-6h Β· after-effects 1-3h
    
    Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 0.75 mg (Smoked).

    The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.

    Tolerance

    Build-up develops over weeks of regular use via CB1 receptor downregulation
    Reset 2–4 weeks for most users; heavy users may need longer

    Tolerance Decay

    Full tolerance 3d Half tolerance 14d Baseline ~28d

    Daily/frequent SCRA use rapidly builds tolerance and blunts cannabis effects for weeks after cessation per clinical observations and community reports; recovery typically requires several weeks’ abstinence. Data quality is limited and inter‑individual variability is high.

    Cross-Tolerances

    Effects dose.wiki

    Positive
    • Pain relief
    • Stimulation
    Negative
    • Dry mouth
    • Tachycardia
    • Nausea/vomiting
    • Strong dysphoria on comedown
    • Nausea
    Neutral
    • Red eyes
    • Spontaneous bodily sensations
    • Vasodilation
    Positive
    • Euphoria
    • Thought connectivity
    • Mindfulness
    • Conceptual thinking
    Negative
    • Anxiety
    • Paranoia
    Neutral
    • Rapid, intense intoxication
    • Anxiolysis or severe anxiety/panic
    • Time distortion
    • Dissociation at high doses
    Positive
    • Increased music appreciation
    • Auditory acuity enhancement
    Negative
    • Dehydration
    Neutral
    • Visual sharpening or mild pseudo-hallucinations
    • Dulled perception
    • Auditory distortion
    • Changes in felt gravity
    • Perception of bodily heaviness
    • Appetite intensification
    • Drifting

    Combinations

    Cross-Check ADBICA with another substance

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