alpha-PCYP - Substance Search

Summary TheDrug.Wiki

α-PCYP is a potent synthetic stimulant of the substituted cathinone class, structurally related to α-PVP with a cyclohexyl ring replacing the propyl chain. Research indicates it is approximately twice as potent as α-PVP at inhibiting dopamine transporters. It produces strong stimulating and euphoric effects with lower compulsivity compared to α-PVP, but still carries high risk for psychological dependence, paranoia, tachycardia, and hypertension.

Dose Information TheDrug.Wiki

Light Common Strong Heavy

Onset, Duration & After-effects TheDrug.Wiki

ROA	Onset	Comeup	Peak	Offset	After Effects
Oral	20-60 min	30-60 min	1-3 hrs	2-4 hrs	24-24 hrs
Insufflated	5-15 min	15-30 min	30-90 min	1-2 hrs	24-24 hrs

Effect Profile

Scores (1–10) curated from multiple sources:

Effect keyword matching from PsychonautWiki catalog
Weighted by importance: core (×3), major (×2), minor (×1)

Full methodology

Stimulant 6.1

Strong 6/10

Strong euphoria and anxiety/jitters with moderate focus, mild stimulation

Stimulation / Energy ×3

5

stimulation wakefulness

Euphoria / Mood Lift ×2

10

physical euphoria euphoria cognitive euphoria motivation enhancement

Focus / Productivity ×2

7

focus enhancement motivation enhancement thought acceleration

⚠ Anxiety / Jitters ×1

10

anxiety paranoia increased heart rate teeth grinding vasoconstriction sweating

Based on reports from:

Erowid Experience Reports PsychonautWiki alpha-PCYP

Tolerance

Build-up develops over days to weeks of regular use

Reset 3–7 days for acute; 1–3 weeks for full reset

Tolerance Decay

Full tolerance 2d Half tolerance 7d Baseline ~14d

Tolerance appears to build rapidly with binges and decays over 1–4 weeks, extrapolated from stimulant class patterns and community accounts; data remain anecdotal, so spacing sessions by several weeks is prudent. Avoid consecutive-day use.