alpha-PiHP - Substance Search

Summary TheDrug.Wiki TripSit

Alpha-PiHP is a potent synthetic cathinone and positional isomer of alpha-PHP, with significantly higher potency than cocaine and methamphetamine as a dopamine transporter inhibitor. It typically appears as white to off-white powder and is consumed orally, insufflated, or vaporized. The substance has been linked to fatal intoxications and severe adverse effects including cardiac complications, psychosis, and seizures.

Dose Information TheDrug.Wiki TripSit

ROA	Light	Common	Strong	Heavy
Oral	5-15mg	15-30mg	30-50mg	50mg+
Insufflated	3-10mg	10-25mg	25-40mg	40mg+
Vaporized	2-10mg	10-20mg	20-30mg	30mg+
Vapourized	2-10mg	10-20mg	20-30mg	30mg+

Light Common Strong Heavy

Onset, Duration & After-effects TheDrug.Wiki TripSit

ROA	Onset	Peak	Offset	After Effects
Oral	30-60 min	1-2 hrs	2-5 hrs	6-12 hrs
Insufflated	1-2 min	1-2 hrs	2-4 hrs	6-12 hrs
Vapourized	1 min	1-3 hrs	-	6-12 hrs

Effect Profile

2 reports

Scores (1–10) curated from multiple sources:

Effect keyword matching from PsychonautWiki catalog
Weighted by importance: core (×3), major (×2), minor (×1)

Full methodology

Empathogen 3.4

Light+ 3/10

Moderate stimulation and euphoria with mild sensory enhancement

Empathy / Social Openness ×3

0

Euphoria / Mood Elevation ×2

6

euphoria cognitive euphoria

Stimulation ×1

7

stimulation wakefulness teeth grinding increased heart rate

Sensory Enhancement ×1

5

tactile enhancement increased libido

Stimulant 5.4

Moderate+ 5/10

Strong anxiety/jitters with moderate euphoria and focus, mild stimulation

Stimulation / Energy ×3

5

stimulation wakefulness

Euphoria / Mood Lift ×2

7

euphoria cognitive euphoria motivation enhancement

Focus / Productivity ×2

7

focus enhancement thought acceleration motivation enhancement

⚠ Anxiety / Jitters ×1

10

anxiety paranoia increased heart rate teeth grinding vasoconstriction

Based on reports from:

Erowid Experience Reports PsychonautWiki alpha-PiHP

Tolerance

Build-up develops over days to weeks of regular use

Reset 3–7 days for acute; 1–3 weeks for full reset

Tolerance Decay

Full tolerance 1d Half tolerance 3d Baseline ~14d

Within‑session acute tolerance to euphoria rises rapidly; next‑day effects are often blunted while side‑effects remain. Rough return to baseline sensitivity typically requires 1–2 weeks after heavy use. Data primarily from user reports; individual variability high.