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    Amitriptyline

    Aliases: Elavil, Levate

    Categories

    Depressant
    Amitriptyline structure

    Summary Erowid

    Amitriptyline HCl is a tricyclic antidepressant used in the treatment of depression and occasionally sleep disorders.

    Dose Information pw-substancebox

    ROA Light Common Strong Heavy
    Oral 20-50mg 50-100mg 100-150mg 200mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects pw-substancebox

    ROA Total
    Oral 10-28 hrs

    Tolerance

    Build-up varies by mechanism; therapeutic tolerance may develop over weeks of regular use
    Reset typically days to weeks after discontinuation

    Effects

    Positive
    • Muscle relaxation
    • Physical euphoria
    • Anxiolytic
    Negative
    • Motor impairment
    • Respiratory depression
    • Nausea
    Neutral
    • Sedation
    • Itchiness
    • Sedative
    • Dystaxia
    Positive
    • Reduced anxiety
    • Anxiety suppression
    • Cognitive euphoria
    • Euphoria
    Negative
    • Dizziness
    • Amnesia
    • Motor control loss
    • Thought deceleration
    • Compulsive redosing
    • Constipation
    Positive
    • Increased music appreciation
    • Increased libido
    Negative
    • Disinhibition
    • Appetite suppression
    • Double vision
    • Dehydration
    • Light sensitivity
    Neutral
    • Dulled perception
    • Internal hallucination
    • Internal hallucinations

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