As I mentioned in a previous post about having a vial of Amobarbital, I was brave enough to go ahead and use it, after having an awful experience with Secobarbital. And this one was definitely worth it. In fact I will go as far as saying that it was better than Heroin.
Amobarbital
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 2 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- PubChem toxicity data
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 2 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- PubChem toxicity data
Aliases: Blues, Amytal, Blue birds, Blue velvet, Blue devils
Summary
Amobarbital (formerly sold as Amytal and as half of Tuinal) is an intermediate-acting barbiturate that potentiates and directly activates GABA-A receptors. The therapeutic index is narrow: doses above approximately 1.5 g have produced fatal respiratory depression. Because its elimination half-life averages 24 hours, next-day cognitive and motor impairment is common.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 50mg | 50-75mg | 75-150mg | 150mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 15-30 min | 30-60 min | 1-4 hrs | 3-5 hrs | 5-9 hrs |
| Intravenous | 1-2 min | 5-10 min | 1-4 hrs | 3-5 hrs | 5-9 hrs |
| Intramuscular | 5-15 min | 15-30 min | 1-4 hrs | 3-5 hrs | 5-9 hrs |
Add to PsychonautWiki Journal
The PsychonautWiki Journal logging app doesn't include every substance. To track Amobarbital there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:
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Import this file as custom substances
and you get "Amobarbital (Substance Search)" with every
route's full dose ladder and timeline, no typing. Works on iOS and
Android (v15+); the format is confirmed by the app's
developer. The manual values below work for older
versions.
Name
Amobarbital
Unit
mg
Description
Amobarbital Source: SubstanceSearch (substancesearch.com) Oral dose (mg): light 50 · common 50-75 · strong 75-150 · heavy 150+ Intravenous dose (mg): threshold 50 Intramuscular dose (mg): threshold 40 Oral duration: onset 15-30m · come-up 0.5-1h · peak 1-4h · offset 3-5h · total 5-9h · after-effects 2-12h Intravenous duration: onset 1-2m · come-up 5-10m · peak 1-4h · offset 3-5h · total 5-9h · after-effects 2-12h Intramuscular duration: onset 5-15m · come-up 15-30m · peak 1-4h · offset 3-5h · total 5-9h · after-effects 2-12h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 62.5 mg (Oral).
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
Tolerance
Build-up
varies by mechanism; therapeutic tolerance may develop over weeks of regular use
Reset
typically days to weeks after discontinuation
Tolerance Decay
Full tolerance
7d
Half tolerance
14d
Baseline
~28d
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Tolerance to sedative/hypnotic effects rises quickly with continuous daily use and decays slowly; risk of dose escalation is high because lethal dose does not increase proportionally. Cross‑tolerance with benzodiazepines/Z‑drugs is partial and unreliable for withdrawal management without medical oversight.
Cross-Tolerances
Effects
Positive
- Anxiolysis
- Muscle relaxation
- Anxiolytic
- Muscle Relaxant
Negative
- Ataxia
- Nystagmus
- Respiratory depression
- Sedation
- Slurred speech
- Sedative
- Dystaxia
- Hypnotic
Positive
- Euphoria
- Reduced anxiety
- Cognitive Euphoria
Negative
- Dizziness
- Cognitive suppression
- Anterograde amnesia
- Dream suppression
- Delusions of sobriety
- Amnesia
- Emotional dampening
Positive
- Tactile Enhancement
- Increased Music Appreciation
- Color enhancement
Negative
- Disinhibition
- Decreased Libido
- Acuity Suppression
- Dehydration
- Light sensitivity
- Dulled perception
Community Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.
Bluelight 1 thread 1 neutral visit
Amobarbital's nerd page
Pharmacology, chemical data, effect profiles, and more
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Helpful Links
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