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    Amphetamine

    Aliases: Pep, Dex, Amph, Pepp, Speed, amphetamines, amphetamin, amfetamine, hearts

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    Amphetamine structure

    Summary PsychonautWiki

    Lisdexamfetamine (also known as lisdextroamphetamine, L-lysine-dextroamphetamine, or lisdexamfetamine dimesylate when under the brand names Elvanse, Tyvense, and Vyvanse) is a stimulant substance of the amphetamine class. It is a "mutual prodrug" (codrug) for d-amphetamine (dextroamphetamine) that is approved for the treatment of attention deficit hyperactivity disorder (ADHD) and moderate to severe binge-eating disorder. Like amphetamine, lisdexamfetamine produces its effects by promoting the release of neurotransmitters dopamine and norepinephrine in the brain.

    Perspectives

    “This is certainly one with which to tread carefully. Amphetamine is amazing but it certainly takes back what it gives.”

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral BA 75-100% 5-10mg 10-25mg 25-50mg 50mg+
    Insufflated BA ~75% 6-15mg 15-30mg 30-50mg 50mg+
    Intravenous BA ~100% 6-15mg 15-30mg 30-50mg 50mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 30-45 min 0.5-2.25 hrs 2.5-4.0 hrs 2.0-3.0 hrs 3.0-6.0 hrs 6.0-8.0 hrs
    Insufflated 1-4 min 30-90 min 1.0-2.0 hrs 1.5-3.0 hrs 2.0-4.0 hrs 3.0-6.0 hrs
    Intravenous 0 min 0 min 2.0-4.0 hrs 1.0-2.0 hrs 1.0-12.0 hrs -

    Tolerance

    Build-up develops over days to weeks of regular use
    Reset 3โ€“7 days for acute; 1โ€“3 weeks for full reset

    Effects TheDrug.Wiki TripSit PsychonautWiki

    Positive
    • Stimulation
    • Bronchodilation
    • Increased alertness
    • Physical euphoria
    Negative
    • Increased Heart Rate
    • Teeth Grinding
    • Dry mouth
    • Vasoconstriction
    • Abnormal heartbeat
    • Increased blood pressure
    • Increased perspiration
    • Nausea
    • Temporary erectile dysfunction
    • Flushing of the face
    • Tachycardia
    • Insomnia
    • Pupil dilation
    Neutral
    • Elevated heartrate
    • Frequent urination
    • Reduced appetite
    • Increased body temperature
    • Difficulty urinating
    • Restless legs
    • Spontaneous bodily sensations
    • Increased bodily temperature
    • Brightness alteration
    • Reflex syncope
    • Sleep paralysis
    • Stamina intensification
    Positive
    • Euphoria
    • Focus Enhancement
    • Motivation Enhancement
    • Wakefulness
    • Cognitive euphoria
    • Analysis enhancement
    • Memory enhancement
    • Increased motivation
    • Cognitive enhancement
    Negative
    • Anxiety
    • Compulsive redosing
    • Cognitive fatigue
    • Depression
    • Irritability
    • Thought deceleration
    • Paranoia
    • Emotion suppression
    • Dream suppression
    • Psychosis
    • Mania
    • Motivation depression
    • Cognitive impairment
    Neutral
    • Thought Acceleration
    • Time Distortion
    • Increased focus
    • Racing thoughts
    • Thought organization
    • Ego inflation
    • Suggestibility suppression
    • Focus intensification
    • Illusion
    Positive
    • Increased Libido
    • Tracers
    • Increased music appreciation
    • Tactile enhancement
    • Increased libido
    Negative
    • Appetite Suppression
    • Dehydration
    • Appetite suppression
    Neutral
    • Drifting
    • Color Enhancement and Suppression

    Combinations TripSit

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