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    Amphetamine Well-documented
    Well-documented
    Multiple authoritative sources agree on dosing and effects.
    • 7 corroborating sources
    • 3 ROAs with full dose ladders
    • duration data present
    • 18 combo interactions documented
    • PubChem toxicity data

    Aliases: Pep, Dex, Amph, Pepp, Speed, amphetamines, amphetamin, amfetamine, hearts

    Summary PsychonautWiki

    Amphetamine (also known as alpha-methylphenethylamine, amfetamine, speed, or by brand names including Adderall, Dexedrine and Tentin) is a classical stimulant substance of the phenethylamine class. It is the parent compound of the substituted amphetamines, a diverse group that includes methamphetamine, MDMA, cathinone, and bupropion. The mechanism of action involves promoting release of the neurotransmitters dopamine and norepinephrine.

    Perspectives

    “This is certainly one with which to tread carefully. Amphetamine is amazing but it certainly takes back what it gives.”

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral BA 75-100% 5-10mg 10-25mg 25-50mg 50mg+
    Insufflated BA ~75% 6-15mg 15-30mg 30-50mg 50mg+
    Intravenous BA ~100% 6-15mg 15-30mg 30-50mg 50mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 30-45 min 0.5-2.25 hrs 2.5-4 hrs 2-3 hrs 3-6 hrs 6-8 hrs
    Insufflated 1-4 min 30-90 min 1-2 hrs 1.5-3 hrs 2-4 hrs 3-6 hrs
    Intravenous - - 2-4 hrs 1-2 hrs 1-12 hrs -

    Effect Profile

    625 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Validated against 545 Erowid trip reports
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Stimulant 6.8
    Strong+ 7/10

    Strong focus with moderate stimulation, mild euphoria and anxiety/jitters

    Stimulation / Energy ×3
    7
    stimulation wakefulness

    “The effect of that tiny bit was so intense I couldn't sleep for 3 days (I lay there at night eyes closed for 8+ hours strait, 2 nights in a row, totally awake, mind flying like crazy trying to sleep).”

    Inlakesh bluelight

    “also i'm going to buy an over the counter pain killer because it helps alot, but i was wondering is it true caffeine enhances the euphoria and feeling of meth, because i've tried this once and...”

    forbiddenlife5 bluelight
    Euphoria / Mood Lift ×2
    5
    physical euphoria euphoria cognitive euphoria motivation enhancement increased motivation

    “If you have a decent size shot of good quality meth that is diluted half water half dope you will prolly get an amazing rush.”

    linzlandexpress bluelight

    “The way your heart beats and your head rushes, it's intense and amazing..”

    mav3rick bluelight
    Focus / Productivity ×2
    9
    focus enhancement analysis enhancement cognitive enhancement memory enhancement motivation enhancement thought acceleration

    “so anyways today i went to buy some, and instead of doing the whole bag of 20 dollars worth like i always do, for someone with no tolerance its too much, and doesn't make you feel anymore amazing...”

    forbiddenlife5 bluelight

    “Sometimes I will be productive......but sometimes I am taken hostage by my computer!”

    linzlandexpress bluelight
    Anxiety / Jitters ×1
    5
    anxiety paranoia increased heart rate teeth grinding tachycardia vasoconstriction

    “my only source of info on this was the internet on my phone so i searched google for how to properly inject meth, how to shoot up, how to hit a vein, all that stuff but i couldnt find any type of...”

    justkeepswimming bluelight

    “In the mean time I ruined our friendship because my desperate need to be with him was Appearant and it scared him.”

    Justdancer bluelight

    User Experience

    focus “so anyways today i went to buy some, and instead of doing the whole bag of 20 dollars worth like i always do, for someone with no tolerance its too much, and doesn't make you feel anymore amazing...” — forbiddenlife5, bluelight

    Tolerance

    Build-up develops over days to weeks of regular use
    Reset 3–7 days for acute; 1–3 weeks for full reset

    Tolerance Decay

    Half tolerance 7d Baseline ~14d

    Subjective tolerance to euphoria and focus builds quickly with consecutive‑day use and can take weeks to meaningfully recede; cross‑tolerance exists across amphetamine congeners. Data are primarily from user communities rather than controlled trials.

    Cross-Tolerances

    Effects Erowid Bluelight

    Aggregated from 545 Erowid and 80 Bluelight experience reports

    Positive Effects 48

    Stimulation 51.7% 88%
    Sociability Enhancement 48.0% 86%
    Thought Acceleration 46.0% 83%
    Euphoria 44.2% 89%
    Focus Enhancement 37.6% 86%
    Empathy 26.3% 81%
    Music Enhancement 22.7% 85%
    Tactile Enhancement 16.1% 85%
    Contentment 16.0% 79%
    Libido Enhancement 16.0% 82%
    Tingling 14.0% 82%
    Body High 11.6% 79%
    Color Enhancement 10.6% 73%
    Joy 10.0% 85%
    Lightness 10.0% 80%
    Confidence 8.0% 84%
    Introspection 7.9% 88%
    Creativity Enhancement 6.7% 82%
    Emotional Openness 6.0% 80%
    Awe 6.0% 77%

    Adverse Effects 75

    Anxiety 47.4% 81%
    Insomnia 38.0% 87%
    Body Load 24.0% 74%
    Confusion 23.2% 81%
    Paranoia 22.0% 80%
    Thought Disorganization 16.0% 81%
    Visual Distortions 14.8% 79%
    Increased Heart Rate 14.7% 70%
    Focus Suppression 14.0% 74%
    Dry Mouth 14.0% 79%
    Tremor 14.0% 81%
    Irritability 12.0% 75%
    Fear 12.0% 88%
    Dysphoria 12.0% 84%
    Auditory Effects 11.9% 85%
    Nausea 10.7% 87%
    Time Dilation 10.0% 77%
    Vomiting 10.0% 92%
    Memory Suppression 9.2% 82%
    Sweating 8.0% 86%

    Combinations TripSit

    Cross-Check Amphetamine with another substance

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.

    Erowid 8 reports 3 positive 3 neutral 2 cautionary visit
    Sweaty, Jittery, Fun & Productive positive exp #115537

    Amphetamines (Adderall) – Sweaty, Jittery, Fun & Productive This report is part of an eight-report collection. The collection consists of a summary report that is retrospective and generalized in nature as well as seven [of which this is one] more detailed chronicles of my experiences with various chemicals used intent...

    Anatoli Smorin · Amphetamines (Adderall)
    Beginning of a Spiritual Journey positive exp #63280

    I am writing this report for a number of reasons. Foremost is that I've always wanted to write a report but never felt I had the 'material' worthy of it, I hope to describe an aspect of this drug that is often overlooked, that being that its potential for inducing spiritual experiences is quite powerful, and, related t...

    Klaus · Amphetamines · 1 tablet oral / 1 tablet oral / 0.5 tablets insufflated
    The Beginning of Self-Knowledge positive exp #48787

    'Speed puts the 'Fun' in 'Profundity'' - A close friend of mine, after experiencing a Fountain-of-Youth stream of thoughts and ideas. Several months ago, a person who was then a very new friend to me and who is now one of my truly closest companions split the crushed contents about six of his 20mg Adderall capsules wit...

    The Seeker · Amphetamines (Adderall) · 60 mg insufflated
    Totally Relaxed neutral exp #38517

    Let me begin by giving you a brief history of myself. I’m currently a junior in high school. I started smoking weed when I was in 8th grade after being convinced by a very close friend how enjoyable it is.

    Estiky · Amphetamines (Adderall) · oral
    Dabblings With Amphetamines neutral exp #90920

    I know nobody actually reads the background information, but I’ll open with a little bit about my drug experiences and well as a little life background information that some may find helpful. First, I grew up from a baby to about 9 years old in a small town in Michigan named Holland.

    CrazyChemist · 50 mg oral / 45 mg oral / 105 mg oral / repeated smoked
    A Blissful Week and a Half neutral exp #106287

    Background: I'd like to start off by giving a short synopsis of myself at the time of my Adderall experience just so you get a feel for the person who was using the drug and so you may understand all factors that played into my outcome with the drug.

    AustinRN · Amphetamines (Adderall) · 20 - 50 mg oral / 150 mg oral
    Addiction Is No Longer an Issue cautionary exp #110266

    I will give a brief history of my experience with drugs and addictions in general. Ever since I was little, I struggled with major anxiety, especially in social situations. I always avoided human contact whenever possible, and was never naturally a friendly person.

    J._Nyb · Amphetamines (Adderall)
    Action ---> Reaction (The Pros and the Cons) cautionary exp #70997

    INTRODUCTION: I am a 16-year-old student in a upper-middle class high school where shitty hydroponic is often given hyperboles such as “the best fucking crazy dro in the land”, where it is almost impossible to retrieve anything beyond weed without the right connections (which most people do not exactly have).

    The Seeker · Amphetamine (Adderall XR) · 60 mg oral
    Bluelight 7 threads 5 neutral 2 cautionary visit
    Iv Amphetamine Almost First Time Very Experienced neutral

    First some insights on my experience and into the European street amp market: So I've been trying to get off all drugs aside from pot. I tried to lay off pot as well for uni's sake, but I have to realize I won't make it anytime soon. Amphetamine, MDPV, Opiates were all used daily and kicked with ease.

    scraped 2026-03-14
    Amphetamine Experienced Mouthgrinding On The Speed Edge neutral

    I haven't seen any speed tripreports here. So I thought I'd post mine. Prior to this, it had been about 8-9 months since my last speed use. I used to do speed once in a week maximum, no consecutive days. I used it at least once a month. Only once did I take a whole gram.

    scraped 2026-03-14
    Amphetamine 200 200mg First Time Eternal Talkativeness And Sleep Deprivation neutral

    TR Amphetamine #1 Title: Eternal talkativeness and sleep deprivation with nice body buzz and euphoria Substance: Amphetamine or Met-amphetamine Substance experience : 1rd time Dosage: 200mg insufflated 200mg insufflated at T +00:40 Please note, substance purity UNKNOWN! Gender: Male Weight: 84 kg Height: 178 cm Age: 26...

    scraped 2026-03-14
    Unknown Blotter 4th Time Hearts Blotter neutral

    Bromo-Dragonfly(?) -- 4th time -- Hearts Blotter On friday night i had rolled on some red scorpians, and knew they were good rolls. During rolling on these scorpians i had the realization that i had "lost the magic." I was somewhat pissed off that, i had not only did not roll that night, but i did not sleep.

    scraped 2026-03-14
    Amphetamine Experienced Reflective Essay neutral

    So I wrote a first draft reflective essay on my previous amphetamine use in the past, it's fairly crappy (for an English 100 college course) so sorry about the wordiness. Anyway, tell me what you guys think, thanks! 09/06/06 English 100 Thunder Perfect Mind 1. Euphoria Standing. Waiting.

    scraped 2026-03-14
    4 Day Pill Amphetamine Binge Experienced cautionary

    Hello, Ok, so let me start, this is a 4 day binge that started last wednesday and ended saturday night (well sunday early hours), i did a total of 20 something pills and 4.2 g of paste (speed). i will start my report by day, so let me start on wednesday. Wednesday: Ok, so the day started, we had a normal day...

    scraped 2026-03-14
    Amphetamine 100 Mg First Time Od Nightmare Trip cautionary

    I got a quantity of 99+% pure, lab-quality amphetamine. I didn’t know that was unusual at the time. It was a fine white powder that came in a little baggie. I quickly looked up a recreational dose for amphetamine, and most sources said about 60 mg (looking back, this was probably referring to the cut amount).

    scraped 2026-03-14

    Bluelight Reference Guide Bluelight

    Safer Use of Stimulants FAQ

    Bluelight’s Safer Use of Stimulants FAQ covers amphetamine, methamphetamine, Adderall, Vyvanse and related compounds: hydration, magnesium, tolerance, neurotoxicity, redose patterns.

    Read full thread on Bluelight →

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