When I first heard of the Βracetam family of drugs I was extremely intrigued by a nootropic that proported to have no crash, no addictive potential, and relatively few side effects. It was like a drug that completed the human brain.
Aniracetam
Well-documented
Well-documented
Multiple authoritative sources agree on dosing and effects.
- 5 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- PubChem toxicity data
- classified Research-chemical
Well-documented
Multiple authoritative sources agree on dosing and effects.
- 5 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- PubChem toxicity data
- classified Research-chemical
Aliases: Sarpul, Sarple, Ampamet, Referan, Draganon
Summary
Fat-soluble compound requiring dietary fat for optimal absorption. Oral bioavailability of parent drug is very low (~10%); most central activity believed to come from active metabolites (notably N-anisoyl-GABA and 2-pyrrolidinone). Users often stack with choline sources (CDP-choline, alpha-GPC) to reduce racetam-type headaches, though clinical necessity is unproven.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 500-1200mg | 1200-1800mg | 1800-2400mg | 2400mg+ |
| Sublingual | 500-1200mg | 1200-1800mg | 1800-2400mg | 2400mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 20-90 min | 30-60 min | 1-2 hrs | 1-2 hrs | 2-4 hrs |
| Sublingual | 5-30 min | 15-30 min | 1-2 hrs | 1-2 hrs | 2-4 hrs |
Tolerance
Build-up
develops over 1β4 weeks of regular use
Reset
days to weeks depending on duration of use
Tolerance Decay
Full tolerance
21d
Half tolerance
7d
Baseline
~14d
Acute tolerance: develops within a single session β the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Patterns are largely anecdotal. Many users rotate racetams or limit use to 2β4 days/week to preserve effects. Headache propensity appears linked to individual cholinergic sensitivity. Evidence base: community reports and Erowid experience summaries.
Cross-Tolerances
Effects
Aggregated from 18 Erowid experience reports
Positive Effects 7
Focus Enhancement
38.9%
70%
Stimulation
38.9%
70%
Anxiety Suppression
38.9%
70%
Color Enhancement
33.3%
70%
Empathy
22.2%
70%
Music Enhancement
16.7%
70%
Sedation
16.7%
70%
Adverse Effects 1
Confusion
16.7%
70%
Community Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.
Erowid 8 reports 6 neutral 2 cautionary visit
Well-intentioned though misguided prepararation of approximately 2g of Aniracetam, an extremely hydrophobic powder, in a few oz. of fish oil: Knowing it was hydrophobic, erroneously believing it to be lipid soluble, I decided to mix it with fish oil and thereby take two alleged cognitive enhancers at once.
I found myself temporarily exhausted from my commonly researched drugs and decided I would do some reading on the so called Βsmart drugsΒ or ΒnootropicsΒ. Due to the lack of information one researching these drugs can face, it can become hard to make sound conclusions about making a first purchase of one of these produ...
Writing this at least a month after the fact, so consider the times just loose approximates. 00:00 (07:00am) Took approx 450mg of aniracetam in water. It tasted pretty foul, but had an awesome aftertaste that didn't develop for about five minutes and lasted five times that long.
Due to cost concerns, I hand pack my own piracetam and aniracetam capsules. I normally take one aniracetam three times a day and four piracetam three times a day, for a total of about 1600mg aniracetam and 12 grams piracetam. The piracetam is already a higher-than-recommended dose, due to perceived ineffectiveness.
Aniracetram: I am amazed that I'd not heard of this drug (or this entire class of drugs, the racetams) earlier. I've been a student in a 'hardcore' discipline of science at two top universities, so I could always use any help focusing on my work.
I took Aniracetam in 750mg doses four times daily for a duration of one week. I did not take Choline with the Aniracetam, which is what I believe caused my issues. This is purely a conjecture. I am not a doctor or medical professional of any sort. At first blush the effects were quite positive.
In the morning after breakfast I mix equal amounts of aniracetam and choline bitatrate powders into 4oz of juice, it doesn't really dissolve the aniracetam, but it's easy to chug. Starting at 700mg of each, the effects were good, but caused a fishy body odor soon after because of the choline.
Aniracetam's nerd page
Pharmacology, chemical data, effect profiles, and more
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