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    Atomoxetine Encyclopedic
    Encyclopedic
    Typical encyclopedia coverage. Cross-reference for important decisions.
    • 2 corroborating sources
    • 1 ROA with full dose ladder
    • duration data present
    • PubChem toxicity data
    • classified Tentative

    Aliases: Strattera

    Stimulant

    Summary Erowid TripSit

    Atomoxetine is a selective norepinephrine reuptake inhibitor (SNRI) approved as a less stimulating treatment for ADHD in 2002 (U.S.). The precise mechanism by which it produces its therapeutic effects is unknown, but is thought to be related to its SNRI action.

    Dose Information TripSit

    ROA Light Common Strong Heavy
    Oral 10-18mg 18-40mg 40-80mg 80mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TripSit

    ROA Onset Peak After Effects Total
    Oral 15-45 min 8-12 hrs 2-24 hrs 8-12 hrs

    Effect Profile

    35 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Validated against 35 Erowid trip reports
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Stimulant 7.2
    Strong+ 7/10

    Strong stimulation and anxiety/jitters with moderate euphoria and focus

    Stimulation / Energy ×3
    10
    stimulation wakefulness alertness enhancement
    Euphoria / Mood Lift ×2
    7
    euphoria cognitive euphoria
    Focus / Productivity ×2
    7
    ⚠ Anxiety / Jitters ×1
    10
    anxiety restlessness increased heart rate vasoconstriction
    Based on reports from:
    Erowid Experience Reports PsychonautWiki Atomoxetine
    View methodology →

    Tolerance

    Build-up develops over days to weeks of regular use
    Reset 3–7 days for acute tolerance; longer for full reset

    Tolerance Decay

    Full tolerance 1d Half tolerance 10d Baseline ~18d

    Effects Erowid

    Aggregated from 35 Erowid experience reports

    Positive Effects 8

    Focus Enhancement 51.4% 70%
    Stimulation 40.0% 70%
    Euphoria 20.0% 70%
    Empathy 17.1% 70%
    Body High 14.3% 70%
    Tactile Enhancement 11.4% 70%
    Color Enhancement 8.6% 70%
    Music Enhancement 8.6% 70%

    Adverse Effects 6

    Anxiety 45.7% 70%
    Nausea 28.6% 70%
    Headache 20.0% 70%
    Sweating 11.4% 70%
    Increased Heart Rate 8.6% 70%
    Jaw Clenching 8.6% 70%

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.

    Erowid 8 reports 6 neutral 2 cautionary visit
    Avid Caffeiner Switches to Atomoxetine neutral exp #103020

    I was diagnosed with ADHD in late October / early November, 2013. I worked closely with my psychiatrist on dosage after being prescribed Strattera (Atomoxetine). I started on a low dose (10 mg per day) and moved up to an 'average' dose (60 mg per day) but settled down at 40 mg per day.

    Terra · Strattera (Atomoxetine) · oral / oral
    Hardcore Hallucinations neutral exp #43332

    Well it all started 2 days ago when I found a unused bottle of Strattera that was prescribed to me around a year ago. I was feeling like crap so I decided to take one and goto bed (around 10PM?).

    Mad Trails · Atomoxetine (Strattera) · 60 mg oral
    Focus & Energy neutral exp #118468

    Description of mindset & setting: Prescribed 40 mg/day Atomoxetine 12 days ago for adult ADD. Took it as prescribed. Felt focused but not energized or in a better mood (actually felt quite irritable, constipated and lethargic [I had been sleeping till 12pm most days]).

    Illgredient · 40 - 120 mg oral / 500 - 1500 mg oral / oral / oral
    Not What I Expected neutral exp #61063

    I am a 16 year old 130 pound male in reasonably good shape. To give a little background on my experiences, I’ve done copious amounts of marijuana, salvia, methylphenidate, DXM, oxycodone, LSA (morning glory), and diphenhydramine. I went into the night with a positive mindset and environment at my friend’s house.

    GBVsoldier · Atomoxetine (Strattera) · 40 mg oral / 40 mg oral / 40 mg oral
    Helpful neutral exp #49361

    I felt the need to post this report after finding so few reports already listed. As well as none of them really showing how beneficial this drug can be, assuming it's prescribed and used correctly. About 4 months ago upon self diagnoses, I decided to see a psychiatrist regarding the treatment of ADD.

    Matt · 25 mg oral
    Disconnected from the Human Machine neutral exp #35622

    I managed to get 30 of these pills about a month ago. These pills are supposedly for ADHD or depression, but can be used for certain types of dementia as well. This is the only SNRI that the FDA has approved as of yet.

    GJR · 120 mg oral / 120 mg oral
    Robotic Focus cautionary exp #114283

    First day of taking 40mg’s Atomexetine in the morning Initially, as the effects started to kick in, I experienced uncomfortable hot flashes, compulsive yawning and an unpleasant anxiety. This went on for the rest of the day. I felt very off, slightly nauseas, and uncomfortable with my mental state.

    Artie Lewis · 40 mg oral
    Concentration but Not Worth It cautionary exp #78718

    I went to my doctor hinting that I wanted Adderall, since I am in college. I've tried Adderall from my friend multiple times and its a hell of a drug. My doctor decided that Strattera would be better for me. He put me on a dose of 40mg (one pill) for the first three days and then two pills a day from then on.

    domin8 · 40 - 80 mg oral

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