Atomoxetine
Aliases: Strattera
Summary
Atomoxetine is a selective norepinephrine reuptake inhibitor (SNRI) approved as a less stimulating treatment for ADHD in 2002 (U.S.). The precise mechanism by which it produces its therapeutic effects is unknown, but is thought to be related to its SNRI action.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 10-18mg | 18-40mg | 40-80mg | 80mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Peak | Total |
|---|---|---|---|
| Oral | 15-45 min | 8-12 hrs | 8.2-12.8 hrs |
Effect Profile
35 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Validated against 35 Erowid trip reports
- Weighted by importance: core (×3), major (×2), minor (×1)
Stimulant
7.2
Strong+
7/10
Strong stimulation and anxiety/jitters with moderate euphoria and focus
Stimulation / Energy
×3
10
stimulation
wakefulness
alertness enhancement
Euphoria / Mood Lift
×2
7
euphoria
cognitive euphoria
Focus / Productivity
×2
7
Anxiety / Jitters
×1
10
anxiety
restlessness
increased heart rate
vasoconstriction
Based on reports from:
Tolerance
Build-up
develops over days to weeks of regular use
Reset
3–7 days for acute tolerance; longer for full reset
Tolerance Decay
Full tolerance
1d
Half tolerance
10d
Baseline
~18d
Effects
Aggregated from 35 Erowid experience reports
Positive Effects 8
Focus Enhancement
51.4%
70%
Stimulation
40.0%
70%
Euphoria
20.0%
70%
Empathy
17.1%
70%
Body High
14.3%
70%
Tactile Enhancement
11.4%
70%
Color Enhancement
8.6%
70%
Music Enhancement
8.6%
70%
Adverse Effects 6
Anxiety
45.7%
70%
Nausea
28.6%
70%
Headache
20.0%
70%
Sweating
11.4%
70%
Increased Heart Rate
8.6%
70%
Jaw Clenching
8.6%
70%
Pill Identifiers
43
known pill identifiers on record — view imprints, colors, shapes, and images
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