Atomoxetine - Substance Search

Summary Erowid TripSit

Atomoxetine is a selective norepinephrine reuptake inhibitor (SNRI) approved as a less stimulating treatment for ADHD in 2002 (U.S.). The precise mechanism by which it produces its therapeutic effects is unknown, but is thought to be related to its SNRI action.

Dose Information TripSit

ROA	Light	Common	Strong	Heavy
Oral	10-18mg	18-40mg	40-80mg	80mg+

Light Common Strong Heavy

Onset, Duration & After-effects TripSit

ROA	Onset	Peak	After Effects	Total
Oral	15-45 min	8-12 hrs	2-24 hrs	8-12 hrs

Effect Profile

35 reports

Scores (1–10) curated from multiple sources:

Effect keyword matching from PsychonautWiki catalog
Validated against 35 Erowid trip reports
Weighted by importance: core (×3), major (×2), minor (×1)

Full methodology

Stimulant 7.2

Strong+ 7/10

Strong stimulation and anxiety/jitters with moderate euphoria and focus

Stimulation / Energy ×3

10

stimulation wakefulness alertness enhancement

Euphoria / Mood Lift ×2

7

euphoria cognitive euphoria

Focus / Productivity ×2

7

⚠ Anxiety / Jitters ×1

10

anxiety restlessness increased heart rate vasoconstriction

Based on reports from:

Erowid Experience Reports

Add to PsychonautWiki Journal

The PsychonautWiki Journal logging app doesn't include every substance. To track Atomoxetine there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:

⬇ Download import file Import this file as custom substances and you get "Atomoxetine (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer. The manual values below work for older versions.

Name

Atomoxetine

Unit

mg

Description

Atomoxetine
Source: SubstanceSearch (substancesearch.com)

Oral dose (mg): light 10-18 · common 18-40 · strong 40-80 · heavy 80+

Oral duration: onset 15-45m · peak 8-12h · total 8-12h · after-effects 2-24h

Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 29 mg (Oral).

The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.

Tolerance

Build-up develops over days to weeks of regular use

Reset 3–7 days for acute tolerance; longer for full reset

Tolerance Decay

Full tolerance 1d Half tolerance 10d Baseline ~18d

Effects Erowid

Aggregated from 35 Erowid experience reports

Positive Effects 8

Focus Enhancement 51.4% 70%

Stimulation 40.0% 70%

Euphoria 20.0% 70%

Empathy 17.1% 70%

Body High 14.3% 70%

Tactile Enhancement 11.4% 70%

Color Enhancement 8.6% 70%

Music Enhancement 8.6% 70%

Adverse Effects 6

Anxiety 45.7% 70%

Nausea 28.6% 70%

Headache 20.0% 70%

Sweating 11.4% 70%

Increased Heart Rate 8.6% 70%

Jaw Clenching 8.6% 70%

Community Trip Reports

Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.

Erowid 8 reports 2 positive 2 neutral 4 cautionary visit

Avid Caffeiner Switches to Atomoxetine positive exp #103020

I was diagnosed with ADHD in late October / early November, 2013. I worked closely with my psychiatrist on dosage after being prescribed Strattera (Atomoxetine). I started on a low dose (10 mg per day) and moved up to an 'average' dose (60 mg per day) but settled down at 40 mg per day.

Hardcore Hallucinations cautionary exp #43332

Well it all started 2 days ago when I found a unused bottle of Strattera that was prescribed to me around a year ago. I was feeling like crap so I decided to take one and goto bed (around 10PM?).

Focus & Energy cautionary exp #118468

Description of mindset & setting: Prescribed 40 mg/day Atomoxetine 12 days ago for adult ADD. Took it as prescribed. Felt focused but not energized or in a better mood (actually felt quite irritable, constipated and lethargic [I had been sleeping till 12pm most days]).

Not What I Expected positive exp #61063

I am a 16 year old 130 pound male in reasonably good shape. To give a little background on my experiences, Ive done copious amounts of marijuana, salvia, methylphenidate, DXM, oxycodone, LSA (morning glory), and diphenhydramine. I went into the night with a positive mindset and environment at my friends house.

Helpful neutral exp #49361

I felt the need to post this report after finding so few reports already listed. As well as none of them really showing how beneficial this drug can be, assuming it's prescribed and used correctly. About 4 months ago upon self diagnoses, I decided to see a psychiatrist regarding the treatment of ADD.

Disconnected from the Human Machine neutral exp #35622

I managed to get 30 of these pills about a month ago. These pills are supposedly for ADHD or depression, but can be used for certain types of dementia as well. This is the only SNRI that the FDA has approved as of yet.

Robotic Focus cautionary exp #114283

First day of taking 40mgs Atomexetine in the morning Initially, as the effects started to kick in, I experienced uncomfortable hot flashes, compulsive yawning and an unpleasant anxiety. This went on for the rest of the day. I felt very off, slightly nauseas, and uncomfortable with my mental state.

Concentration but Not Worth It cautionary exp #78718

I went to my doctor hinting that I wanted Adderall, since I am in college. I've tried Adderall from my friend multiple times and its a hell of a drug. My doctor decided that Strattera would be better for me. He put me on a dose of 40mg (one pill) for the first three days and then two pills a day from then on.

Pill Identifiers

43 known pill identifiers on record — view imprints, colors, shapes, and images

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Atomoxetine's nerd page Pharmacology, chemical data, effect profiles, and more

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Helpful Links

📘 Experience Reports 📖 Erowid 📖 TripSit 📖 PsychonautWiki

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Atomoxetine Encyclopedic Encyclopedic Typical encyclopedia coverage. Cross-reference for important decisions. 2 corroborating sources 1 ROA with full dose ladder duration data present PubChem toxicity data classified Tentative