In general I don't read junk mail, however I had heard on-line pharmacies were easy to order from. So, one day I decide to click the link to the online pharmacy adivertisement jumbled amongst the rest of the spam in my e-mail folder.
Benzphetamine
Well-documented
Well-documented
Multiple authoritative sources agree on dosing and effects.
- 3 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 18 combo interactions documented
- PubChem toxicity data
- dose data not in PW/TripSit (unverifiable)
Well-documented
Multiple authoritative sources agree on dosing and effects.
- 3 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 18 combo interactions documented
- PubChem toxicity data
- dose data not in PW/TripSit (unverifiable)
Aliases: Didrex, Regimex, Inapetyl
Summary
Benzphetamine is prescribed as a short-term appetite suppressant for obesity management. As a prodrug, it metabolizes into amphetamine and methamphetamine in the body, producing stimulant effects. Contraindicated in individuals with cardiovascular disease, moderate to severe hypertension, hyperthyroidism, glaucoma, or history of substance abuse.
Dose Information
Dose basis. Historical therapeutic products were 50 mg tablets (e.g., Didrex). Dosing ranges below synthesize legacy medical use patterns and user reports; substantial interindividual variability exists. Start low, avoid late-day redosing due to long half-life. Information primarily derived from official drug monographs and user reports. (Dose figures and this note are from Drugs.Wiki.)
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 25-50mg | 50-100mg | 100-150mg | 150mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 30-60 min | 60-90 min | 2-4 hrs | 4-8 hrs | 7.5-14.5 hrs |
Effect Profile
4 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Stimulant
5.9
Strong
6/10
Strong anxiety/jitters and focus with moderate euphoria, mild stimulation
Stimulation / Energy
×3
5
stimulation
wakefulness
Euphoria / Mood Lift
×2
7
physical euphoria
cognitive euphoria
motivation enhancement
Focus / Productivity
×2
9
focus enhancement
analysis enhancement
motivation enhancement
thought acceleration
Anxiety / Jitters
×1
10
anxiety
restlessness
increased heart rate
teeth grinding
vasoconstriction
Based on reports from:
Add to PsychonautWiki Journal
The PsychonautWiki Journal logging app doesn't include every substance. To track Benzphetamine there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:
⬇ Download import file
Import this file as custom substances
and you get "Benzphetamine (Substance Search)" with every
route's full dose ladder and timeline, no typing. Works on iOS and
Android (v15+); the format is confirmed by the app's
developer. The manual values below work for older
versions.
Name
Benzphetamine
Unit
mg
Description
Benzphetamine Source: SubstanceSearch (substancesearch.com) Oral dose (mg): threshold 5 · light 25-50 · common 50-100 · strong 100-150 · heavy 150+ Oral duration: onset 0.5-1h · come-up 1-1.5h · peak 2-4h · offset 4-8h · total 7.5-14.5h · after-effects 24h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 75 mg (Oral).
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
Tolerance
Build-up
develops over days to weeks of regular use
Reset
3–7 days for acute; 1–3 weeks for full reset
Tolerance Decay
Half tolerance
3d
Baseline
~21d
Tolerance to anorectic and euphoric effects develops quickly (days–weeks) with repeated use; cross-tolerance likely across amphetamine-class stimulants. Empirical timelines vary; conservative spacing (≥2–3 weeks) reduces rapid tolerance escalation.
Effects
Aggregated from 4 Erowid experience reports
Positive Effects 1
Stimulation
75.0%
70%
Adverse Effects 0
Combinations
Cross-Check Benzphetamine with another substanceCommunity Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.
Erowid 1 report 1 positive visit
Pill Identifiers
8
known pill identifiers on record — view imprints, colors, shapes, and images
→
Benzphetamine's nerd page
Pharmacology, chemical data, effect profiles, and more
→
Helpful Links
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