Summary
Benzphetamine is prescribed as a short-term appetite suppressant for obesity management. As a prodrug, it metabolizes into amphetamine and methamphetamine in the body, producing stimulant effects. Contraindicated in individuals with cardiovascular disease, moderate to severe hypertension, hyperthyroidism, glaucoma, or history of substance abuse. Side effects include elevated heart rate and blood pressure, insomnia, anxiety, and potential for cardiac complications. Use should be limited to a few weeks due to rapid tolerance development and dependence risk.
Dose Information
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | After Effects |
|---|---|---|---|---|---|
| Oral | 30-60 min | 60-90 min | 2-4 hrs | 4-8 hrs | 24 hrs |
Tolerance
Build-up
develops over days to weeks of regular use
Reset
3–7 days for acute; 1–3 weeks for full reset
Effects
Positive
- Stimulation
- Physical euphoria
Negative
- Increased heart rate
- Increased blood pressure
- Dry mouth
- Vasoconstriction
- Restlessness
- Teeth grinding
- Increased perspiration
- Insomnia
Positive
- Focus enhancement
- Motivation enhancement
- Cognitive euphoria
- Wakefulness
- Analysis enhancement
Negative
- Anxiety
- Thought acceleration
- Ego inflation
- Time distortion
- Time Distortion
Positive
- Increased libido
- Tactile Enhancement
- Pattern Recognition Enhancement
- Increased Music Appreciation
- Synaesthesia
Negative
- Appetite suppression
- Light sensitivity
- Dulled perception
- Auditory hallucination
- Auditory distortion