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    Benzphetamine Encyclopedic
    Encyclopedic
    Typical encyclopedia coverage. Cross-reference for important decisions.
    • 2 corroborating sources
    • 1 ROA with full dose ladder
    • duration data present
    • 18 combo interactions documented
    • PubChem toxicity data
    • dose data not in PW/TripSit (unverifiable)

    Aliases: Didrex, Regimex, Inapetyl

    Summary TheDrug.Wiki

    Benzphetamine is prescribed as a short-term appetite suppressant for obesity management. As a prodrug, it metabolizes into amphetamine and methamphetamine in the body, producing stimulant effects. Contraindicated in individuals with cardiovascular disease, moderate to severe hypertension, hyperthyroidism, glaucoma, or history of substance abuse.

    Dose Information TheDrug.Wiki

    ROA Light Common Strong Heavy
    Oral 25-50mg 50-100mg 100-150mg 150mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki

    ROA Onset Peak Offset After Effects Total
    Oral 30-60 min 2-4 hrs 4-8 hrs 24 hrs 8-12 hrs

    Effect Profile

    4 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Stimulant 5.9
    Strong 6/10

    Strong anxiety/jitters and focus with moderate euphoria, mild stimulation

    Stimulation / Energy ×3
    5
    stimulation wakefulness
    Euphoria / Mood Lift ×2
    7
    physical euphoria cognitive euphoria motivation enhancement
    Focus / Productivity ×2
    9
    focus enhancement analysis enhancement motivation enhancement thought acceleration
    Anxiety / Jitters ×1
    10
    anxiety restlessness increased heart rate teeth grinding vasoconstriction

    Tolerance

    Build-up develops over days to weeks of regular use
    Reset 3–7 days for acute; 1–3 weeks for full reset

    Tolerance Decay

    Half tolerance 3d Baseline ~21d

    Tolerance to anorectic and euphoric effects develops quickly (days–weeks) with repeated use; cross-tolerance likely across amphetamine-class stimulants. Empirical timelines vary; conservative spacing (≥2–3 weeks) reduces rapid tolerance escalation.

    Effects Erowid

    Aggregated from 4 Erowid experience reports

    Positive Effects 1

    Stimulation 75.0% 70%

    Adverse Effects 0

    Combinations TripSit

    Cross-Check Benzphetamine with another substance

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.

    Erowid 1 report 1 neutral visit
    Not Quite Adderall neutral exp #27835

    In general I don't read junk mail, however I had heard on-line pharmacies were easy to order from. So, one day I decide to click the link to the online pharmacy adivertisement jumbled amongst the rest of the spam in my e-mail folder.

    VdbGTi · Benzphetamine (Didrex) · 1 tablet oral / 0.5 tablets oral

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