Ok I got prescribed this stuff because I supposedly have depression with phsychotic features. I experimented with insuffalating it before here and there. but when I got this script I decided to snort some, I turned on some music on the 'puter and crushed away. my mood was completely neutral at this time.
Bupropion
Well-documented
Well-documented
Multiple authoritative sources agree on dosing and effects.
- 3 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 18 combo interactions documented
- PubChem toxicity data
Well-documented
Multiple authoritative sources agree on dosing and effects.
- 3 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 18 combo interactions documented
- PubChem toxicity data
Aliases: Zyban, Wellbutrin, Amfebutamone, Wellbutrin xl
Summary
Bupropion is a prescription antidepressant and smoking cessation aid with a dose-dependent risk of seizures, particularly above 450 mg/day. It is contraindicated in individuals with seizure disorders, eating disorders (anorexia or bulimia), or during alcohol/benzodiazepine withdrawal. Unlike most antidepressants, bupropion does not typically cause sexual dysfunction or weight gain.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 150mg/day | 150-300mg/day | 300-450mg/day | 450+mg(notrecommendedduetoseizurerisk) |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Peak | Offset |
|---|---|---|---|
| Oral | 1-2 hrs | 2-4 hrs | 6-24 hrs |
Effect Profile
178 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Validated against 178 Erowid trip reports
- Weighted by importance: core (×3), major (×2), minor (×1)
Stimulant
6.4
Strong
6/10
Strong anxiety/jitters and stimulation with moderate euphoria and focus
Stimulation / Energy
×3
9
stimulation
increased energy
Euphoria / Mood Lift
×2
6
mood lift
motivation enhancement
Focus / Productivity
×2
6
cognitive enhancement
motivation enhancement
Anxiety / Jitters
×1
10
anxiety
restlessness
Based on reports from:
Tolerance
Build-up
develops rapidly, often within a single session; compulsive redosing common
Reset
a few days for acute tolerance
Tolerance Decay
Full tolerance
1h
Half tolerance
4d
Baseline
~5d
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
Aggregated from 178 Erowid experience reports
Positive Effects 11
Stimulation
41.6%
70%
Euphoria
30.9%
70%
Tactile Enhancement
20.2%
70%
Music Enhancement
19.1%
70%
Color Enhancement
19.1%
70%
Focus Enhancement
15.7%
70%
Empathy
11.8%
70%
Body High
9.0%
70%
Introspection
7.3%
70%
Pain Relief
5.1%
70%
Creativity Enhancement
3.4%
70%
Adverse Effects 13
Anxiety
43.3%
70%
Nausea
16.9%
70%
Confusion
15.2%
70%
Seizure
14.0%
70%
Memory Suppression
11.2%
70%
Increased Heart Rate
11.2%
70%
Headache
9.0%
70%
Pupil Dilation
7.9%
70%
Motor Impairment
6.7%
70%
Muscle Tension
6.2%
70%
Psychosis
6.2%
70%
Jaw Clenching
5.1%
70%
Sweating
5.1%
70%
Combinations
Cross-Check Bupropion with another substanceCommunity Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.
Erowid 8 reports 1 positive 3 neutral 4 cautionary visit
I decide to take 450mg of Wellbutrin SR (150mg/pill), purple smileys when held just the right way. I take a shower and emerge refreshed, though I can't tell if they have taken effect; I realize I am wearing a dumb grin - and know now that it has. I sit and watch TV.
I have bipolar disorder & have faithfully been taking Wellbutrin XL 450 mg every morning for the last 4 years. At the time I was not on a mood stabilizer & was in the midst of a major depressive episode. I dont believe that had any effect on the physiological symptoms, however.
from: http://www.nytimes.com/2005/01/25/health/25case.html?oref=login&incamp=article_popular_4 A Pill's Surprises, for Patient and Doctor Alike By RICHARD A. FRIEDMAN, M.D. Published: January 25, 2005 As a psychopharmacologist, I know that every patient responds slightly differently to medication.
I am currently writing this while experiencing the come up of effects. I've tried this on and off the last week or 2. It's a really nice experience, and if you're open minded and have no societal/sexual/religious/etc stigma about rectal administration of a drug, it might work out nicely for you.
Ladies and gentlemen, never try to recreate the following story about a dumb eighteen year old and his anti depressants. This wellbutrin trip is one the of the scariest ordeals I've ever gone through, hallucinations, seizures, and the anxiety/paranoia were just a few of the side effects.
[Erowid Note: The dose described in this report is very high, potentially beyond Erowid's 'heavy' range, and could pose serious health risks or result in unwanted, extreme effects.
Welbutrin XL 12 300mg pills at about 11:30pm The events leading up to the overdose: I had been taking Welbutrin for over a year. 300mg prescribed once a day for depression. I had also been dealing with a cocaine addiction for about 6months. No coke was in my system the time of the overdose.
Bluelight 8 threads 4 neutral 4 cautionary visit
One day I was extremely bored and frustrated that my regular dose of bupropion wasn’t doing much anymore. On impulse, I decided to take a massive dose—around 1 gram. After waiting a while for it to kick in, I started feeling noticeably off.
So I have looked around and found very different reports of snorting wellbutrin. This is mine. I peel the coat off of a 300mg tablet and grind it to a fine powder. I make 8 equally sized lines. I intranasally take 2 lines at a time with 15 minutes between each set.
So, the addict that I am have heard about the stimulant qualities of Welbutrin and have never taken it before tonight. I guess you can say I got a little desperate because who the fuck shoots anti depressants?!?!? Anyways, I got a 300 mg XL pill of bupropion and shaved the coating off easily.
Age - 22 Thought id make an ongoing trip report or experience with my wellbutrin. I was going to write it on a word document for myself to see if it actually worked and to watch my progress. but hey might as well share it for those looking to use meds to treat your depression. To start i was always against meds.
=== WARNING THIS IS LONG, CONTROVERSIAL, WILL PISS YOU OFF ESPECIALLY IF YOU ARE JEWISH, I GIVE ZERO FUCKS AND HOPE THIS WILL BE OF SOME USE TO THE PSYCHEDELIC RESEARCH COMMUNITY AND HOW PSYCHEDELICS (oral cannabis) INTERACTS WITH GEODON AND WELLBUTRIN on someone who is schizoaffective (me).
This took place in 2014 My mother was prescribed welbutrin at 300mg a capsule. I had been going threw this awakening and got to the point where I believed I should die due to these "signs" I have been noticing since the awakening. I grabbed the bottle out of the cabinet and went to my room..
Hello! I recently decided to try snorting a 75 mg IR tablet of bupropion. I have found so many inconclusive and conflicting reports on whether or not this drug has any recreational potential that I decided to try it myself. Yes, I am aware it can cause seizures in higher doses.
Warning: Do NOT do this unless you have access to anticonvulsant medication. I took 2mg of Xanax and 600mg of Gabapentin before ingesting. High doses of bupropion can cause seizures, especially when insufflated.
Pill Identifiers
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