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    Clonidine

    Aliases: Kapvay, Dixarit, Catapres, Haemiton, Duraclon

    Summary PsychonautWiki

    Clonidine (known by the trade names Catapres, Kapvay, Nexiclon, Clophelin, and others) is a depressant substance of the arylaminoimidazoline class. It is primarily used to treat high blood pressure, but can also be used for a variety of conditions that include attention deficit hyperactivity disorder, anxiety disorders, tic disorders, substance withdrawal, migraine, diarrhea, and certain pain conditions.

    Dose Information TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 50-75μg 75-100μg 100-300μg 300μg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TripSit PsychonautWiki

    ROA Onset Peak Offset After Effects Total
    Oral 12-48 min 60-90 min 6-8 hrs 1-4 hours 7.2-10.3 hrs

    Tolerance

    Build-up develops over 1–4 weeks of regular use
    Reset days to weeks depending on duration of use

    Tolerance Decay

    Full tolerance 3d Half tolerance 8d Baseline ~14d

    Effects Erowid

    Aggregated from 25 Erowid experience reports

    Positive Effects 6

    Sedation 44.0% 70%
    Stimulation 28.0% 70%
    Anxiety Suppression 24.0% 70%
    Euphoria 20.0% 70%
    Focus Enhancement 12.0% 70%
    Music Enhancement 12.0% 70%

    Adverse Effects 2

    Increased Heart Rate 16.0% 70%
    Motor Impairment 12.0% 70%

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