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    Disclaimer
    ⚠ Benzodiazepines can cause physical dependence with regular use. Withdrawal can be life-threatening. Never combine with opioids or alcohol.

    Clorazepate

    Aliases: Tranxene, Tranzene, Novo-clopate

    Depressant Benzodiazepine

    Summary TripSit

    Is a prodrug for Desmethyldiazepam which is responsible for most of the therapeutic effects. Has a long half life, with the addition of Desmethyldiazepam as the main metabolite, which makes it much longer.

    Dose Information TripSit

    ROA Light Common Strong Heavy
    Oral 5-10mg 10-20mg 20-40mg 40mg+
    Light Common Strong Heavy

    Benzo Equivalence Calculator

    mg
    15.0 mg Clorazepate
    =
    — mg Diazepam

    ⚠ These are approximate equivalences for educational and cross-tapering reference. Individual response, tolerance, and half-life differences mean actual equivalence varies. Always consult a healthcare provider for tapering guidance.

    Onset, Duration & After-effects TripSit

    ROA Onset Peak After Effects Total
    Oral 20-80 min 8-12 hrs 1-8 hrs 8.3-13.3 hrs

    Effect Profile

    1 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Benzodiazepine 7.4
    Strong+ 7/10

    Strong anxiolysis and euphoria with mild cognitive impairment, low sedation

    Anxiolysis ×3
    10
    anxiety suppression anxiolytic reduced anxiety muscle relaxant
    Sedation / Relaxation ×2
    3
    sedation
    ⚠ Motor / Cognitive Impairment ×1
    4
    amnesia double vision
    Euphoria / Mood Lift ×1
    10
    cognitive euphoria euphoria physical euphoria disinhibition
    Based on reports from:
    Erowid Experience Reports PsychonautWiki Clorazepate
    View methodology →

    Tolerance

    Build-up develops over 1–4 weeks of daily use; hypnotic tolerance faster than anxiolytic tolerance
    Reset weeks to months depending on half-life and duration of use; taper recommended

    Tolerance Decay

    Full tolerance 3d Half tolerance 37d Baseline ~60d

    Effects TripSit

    Positive
    • Anxiolytic
    • Muscle Relaxant
    • Stimulation
    • Physical euphoria
    Negative
    • Increased heart rate
    • Nausea
    Neutral
    • Sedative
    • Dystaxia
    • Hypnotic
    • Sedation
    Positive
    • Reduced anxiety
    • Cognitive euphoria
    • Euphoria
    • Anxiety suppression
    Negative
    • Amnesia
    • Compulsive redosing
    • Anxiety
    • Thought deceleration
    • Dizziness
    Neutral
    • Time distortion
    Positive
    • Increased music appreciation
    • Increased libido
    • Tactile enhancement
    • Color enhancement
    Negative
    • Disinhibition
    • Light sensitivity
    • Dehydration
    • Appetite suppression
    • Double vision
    Neutral
    • Dulled perception

    Combinations TripSit

    Clorazepate's nerd page Pharmacology, chemical data, effect profiles, and more
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    Helpful Links

    💊 Pill Identifier 📘 Experience Reports 📖 TripSit 📖 PsychonautWiki