Clorazepate
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 1 source
- 1 ROA with full dose ladder
- duration data present
- 17 combo interactions documented
- PubChem toxicity data
- 1 source
- 1 ROA with full dose ladder
- duration data present
- 17 combo interactions documented
- PubChem toxicity data
Aliases: Tranxene, Tranzene, Novo-clopate
Summary
Is a prodrug for Desmethyldiazepam which is responsible for most of the therapeutic effects. Has a long half life, with the addition of Desmethyldiazepam as the main metabolite, which makes it much longer.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 5-10mg | 10-20mg | 20-40mg | 40mg+ |
Benzo Equivalence Calculator
| Substance | Equivalent Dose | Potency |
|---|
⚠ These are approximate equivalences for educational and cross-tapering reference. Individual response, tolerance, and half-life differences mean actual equivalence varies. Always consult a healthcare provider for tapering guidance.
Onset, Duration & After-effects
| ROA | Onset | Peak | Total |
|---|---|---|---|
| Oral | 20-80 min | 8-12 hrs | 8-12 hrs |
Effect Profile
1 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong anxiolysis and euphoria with mild cognitive impairment, low sedation
Add to PsychonautWiki Journal
The PsychonautWiki Journal logging app doesn't include every substance. To track Clorazepate there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:
Clorazepate Source: SubstanceSearch (substancesearch.com) Oral dose (mg): light 5-10 · common 10-20 · strong 20-40 · heavy 40+ Oral duration: onset 0.33-1.33h · peak 8-12h · total 8-12h · after-effects 1-8h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 15 mg (Oral).
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
- Anxiolytic
- Muscle Relaxant
- Stimulation
- Physical euphoria
- Increased heart rate
- Nausea
- Sedative
- Dystaxia
- Hypnotic
- Sedation
- Reduced anxiety
- Cognitive euphoria
- Euphoria
- Anxiety suppression
- Amnesia
- Compulsive redosing
- Anxiety
- Thought deceleration
- Dizziness
- Time distortion
- Increased music appreciation
- Increased libido
- Tactile enhancement
- Color enhancement
- Disinhibition
- Light sensitivity
- Dehydration
- Appetite suppression
- Double vision
- Dulled perception
Combinations
Cross-Check Clorazepate with another substanceHelpful Links
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