Creatine
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 3 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- toxicity data (PsychonautWiki, PubChem)
- 3 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- toxicity data (PsychonautWiki, PubChem)
Aliases: N-amidinosarcosine, Methylguanidoacetic acid, N-carbamimidoyl-n-methylglycine
Summary
Creatine is a naturally occurring amino acid and one of the most well-researched dietary supplements. While generally considered safe at recommended doses (3-5 g/day maintenance), proper hydration is essential to prevent cramping and gastrointestinal distress. Individuals with pre-existing kidney disease should consult a healthcare provider before use.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 1-5g | 5-10g | 10-20g | 20g+ |
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong focus with moderate stimulation, low euphoria and anxiety/jitters
Import into PsychonautWiki Journal
The PsychonautWiki Journal app includes Creatine, but its built-in data can be thinner than ours. Importing this file adds a separate "Creatine (Substance Search)" custom substance with our dose ranges, durations and tolerance, so you can log against whichever you prefer.
Ranges are harm-reduction guidance, not a prescription.
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
- Physical Stimulation
- Stamina Enhancement
- Stimulation
- Increased heart rate
- Nausea
- Headache
- Ataxia
- Muscle twitching
- Motor impairment
- Sedation
- Memory Enhancement
- Motivation Enhancement
- Thought Connectivity
- Analysis Enhancement
- Focus Enhancement
- Anxiety Suppression
- Rejuvenation
- Confusion
- Delirium
- Thought Organization
- Bodily Control Enhancement
- Tracers
- Light sensitivity
- Perception Of Bodily Heaviness
- Visual distortions
- Auditory distortions
- Sensations of floating
- Dulled perception
- Appetite suppressant
- Auditory hallucination
Helpful Links
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