Cyclizine
Summary
First generation antihistamine and anticholinergic drug used to combat nausea and vomiting. Causes drowsiness. Like most antihistamines in high doses it induces delirium and vivid realistic hallucinations.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | - | 25-50mg | - | - |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Peak |
|---|---|---|
| Oral | 10-30 min | 4-8 hrs |
Tolerance
Build-up
develops over 1–4 weeks of regular use
Reset
days to weeks depending on duration of use
Tolerance Decay
Full tolerance
3d
Half tolerance
8d
Baseline
~14d
Effects
Aggregated from 12 Erowid experience reports
Positive Effects 5
Anxiety Suppression
75.0%
70%
Color Enhancement
41.7%
70%
Stimulation
33.3%
70%
Sedation
25.0%
70%
Music Enhancement
25.0%
70%
Adverse Effects 3
Nausea
50.0%
70%
Increased Heart Rate
41.7%
70%
Confusion
25.0%
70%
Cyclizine's nerd page
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