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    Cyclizine

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    Cyclizine structure

    Summary TripSit

    First generation antihistamine and anticholinergic drug used to combat nausea and vomiting. Causes drowsiness. Like most antihistamines in high doses it induces delirium and vivid realistic hallucinations. Probably uncomfortable and not enjoyable.

    Dose Information TripSit

    ROA Light Common Strong Heavy
    Oral - 25-50mg - -
    Light Common Strong Heavy

    Onset, Duration & After-effects TripSit

    ROA Onset Peak After Effects
    Oral 10-30 min 4.0-8.0 hrs 14.0 hrs

    Tolerance

    Build-up develops over 1โ€“4 weeks of regular use
    Reset days to weeks depending on duration of use

    Effects TripSit

    Positive
    • Physical euphoria
    • Muscle relaxation
    Negative
    • Dry mouth
    • Headache
    • Psychomotor impairment
    • Urinary retention
    • Motor impairment
    Neutral
    • Dermatitis
    • And gastrointestinal disturbances
    • Sedation
    Positive
    • Reduced anxiety
    • Anxiety suppression
    • Cognitive euphoria
    • Euphoria
    Negative
    • Dizziness
    • Amnesia
    • Compulsive redosing
    • Motor control loss
    • Thought deceleration
    • Constipation
    Positive
    • Increased music appreciation
    • Increased libido
    Negative
    • Blurred vision
    • Disinhibition
    • Appetite suppression
    • Dehydration
    • Light sensitivity
    • Double vision
    Neutral
    • Dulled perception
    • Internal hallucinations

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