Cyclobenzaprine
Aliases: amrix, apo-cyclobenzaprin, cycoflex, fexmid, flexeril, mk-130, novo-cycloprine
Summary
Muscle relaxant and CNS depressant used to relieve skeletal muscle spasms and associated pain in acute musculoskeletal conditions. Sometimes prescribed off-label for treatment of fibromyalgia or as a sleep aid. Has little recreational value alone, but may potentiate some opioids.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 2-5mg | 5-10mg | 10-15mg | 15mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Peak | Total |
|---|---|---|---|
| Oral | 15-45 min | 6-12 hrs | 6.2-12.8 hrs |
Tolerance
Build-up
sedative effects diminish over 1–2 weeks of daily use
Reset
a few days
Tolerance Decay
Full tolerance
14d
Half tolerance
7d
Baseline
~14d
Tolerance to daytime sedation can develop over several days of repeated use. Given sparse formal data, these values are approximate and based on class inferences and user reports rather than controlled studies.
Cross-Tolerances
Effects
Aggregated from 61 Erowid experience reports
Positive Effects 9
Sedation
50.8%
70%
Stimulation
24.6%
70%
Music Enhancement
23.0%
70%
Euphoria
19.7%
70%
Anxiety Suppression
11.5%
70%
Body High
9.8%
70%
Tactile Enhancement
9.8%
70%
Focus Enhancement
6.6%
70%
Empathy
4.9%
70%
Adverse Effects 4
Confusion
9.8%
70%
Nausea
6.6%
70%
Headache
6.6%
70%
Pupil Dilation
4.9%
70%
Pill Identifiers
18
known pill identifiers on record — view imprints, colors, shapes, and images
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