Cyputylone
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 3 corroborating sources
- 3 ROAs with full dose ladders
- duration data present
- 18 combo interactions documented
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
- 3 corroborating sources
- 3 ROAs with full dose ladders
- duration data present
- 18 combo interactions documented
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
Aliases: N-cyclohexylmethylone
Summary
Cyputylone is structurally similar to methylone with cyclohexyl substitution at the amine nitrogen. Early user reports highlight marked body-load including bruxism, hypertension, nausea, and diarrhea even at lower doses around 25 mg rectal. Insufflated material produces strong nasal numbness and vasoconstriction but relatively minimal euphoria compared to methylone or eutylone.
Dose Information
Dose basis. Ranges are compiled primarily from scattered user reports; human PK and potency are unstudied. Start low, go slow; use an accurate 0.001 g scale. Potency may vary substantially across batches. Avoid redosing for at least 2 hours to reduce stacking-related toxicity. User reports describe strong local anaesthesia/vasoconstriction with limited euphoria; nasal irritation likely. Grind finely; do not share straws; consider skipping this ROA if mucosal damage is a concern. Effects may feel harsher and shorter than oral. (Dose figures and this note are from Drugs.Wiki.)
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 20-60mg | 60-120mg | 120-180mg | 180mg+ |
| Insufflated | 10-30mg | 30-60mg | 60-100mg | 100mg+ |
| Rectal | 15-30mg | 30-60mg | 60-90mg | 90mg+ |
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 20-40 min | 30-60 min | 30-90 min | 2-4 hrs | 3.33-7.17 hrs |
| Insufflated | 5-10 min | 15-30 min | 30-90 min | 2-3 hrs | 2.83-5.17 hrs |
| Rectal | 5-10 min | 15-30 min | 30-90 min | 2-4 hrs | 2.83-6.17 hrs |
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Moderate stimulation, sensory enhancement, and euphoria
Strong anxiety/jitters with moderate euphoria and stimulation, low focus
Add to PsychonautWiki Journal
The PsychonautWiki Journal logging app doesn't include every substance. To track Cyputylone there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:
Cyputylone Source: SubstanceSearch (substancesearch.com) Oral dose (mg): threshold 20 · light 20-60 · common 60-120 · strong 120-180 · heavy 180+ Insufflated dose (mg): threshold 10 · light 10-30 · common 30-60 · strong 60-100 · heavy 100+ Rectal dose (mg): threshold 15 · light 15-30 · common 30-60 · strong 60-90 · heavy 90+ Oral duration: onset 20-40m · come-up 0.5-1h · peak 0.5-1.5h · offset 2-4h · total 3.33-7.17h · after-effects 4-8h Insufflated duration: onset 5-10m · come-up 15-30m · peak 0.5-1.5h · offset 2-3h · total 2.83-5.17h · after-effects 4-8h Rectal duration: onset 5-10m · come-up 15-30m · peak 0.5-1.5h · offset 2-4h · total 2.83-6.17h · after-effects 4-8h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 90 mg (Oral).
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
Tolerance
Tolerance Decay
Acute tolerance can develop within a single session, especially with redosing. Anecdotally, partial tolerance may persist for several days, similar to other serotonergic cathinones. Data quality: low/anecdotal.
Cross-Tolerances
Effects
- Stimulation
- Teeth grinding
- Jaw clenching
- Increased heart rate
- Increased blood pressure
- Nausea
- Temperature regulation suppression
- Pupil dilation
- Vasoconstriction
- Difficulty urinating
- Cognitive euphoria
- Wakefulness
- Alertness enhancement
- Euphoria
- Motivation enhancement
- Compulsive redosing
- Anxiety
- Talkativeness
- Time distortion
- Thought acceleration
- Increased music appreciation
- Tactile enhancement
- Increased libido
- Tracers
- Color enhancement
- Dehydration
- Light sensitivity
- Appetite suppression
- Disinhibition
- Spontaneous physical sensations
Combinations
Cross-Check Cyputylone with another substanceHelpful Links
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