Summary
Cyputylone is structurally similar to methylone with cyclohexyl substitution at the amine nitrogen. Early user reports highlight marked body-load including bruxism, hypertension, nausea, and diarrhea even at lower doses around 25 mg rectal. Insufflated material produces strong nasal numbness and vasoconstriction but relatively minimal euphoria compared to methylone or eutylone. The substance has a brief peak with significant residual stimulation promoting compulsive redosing. Suspected mild MAO-B inhibition warrants avoiding tyramine-rich foods for 24 hours post-dose until further data emerge.
Dose Information
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | After Effects |
|---|---|---|---|---|---|
| Oral | 20-40 min | 30-60 min | 30-90 min | 2-4 hrs | 4-8 hrs |
| Insufflated | 5-10 min | 15-30 min | 30-90 min | 2-3 hrs | 4-8 hrs |
| Rectal | 5-10 min | 15-30 min | 30-90 min | 2-4 hrs | 4-8 hrs |
Tolerance
Build-up
develops rapidly, often within a single session; compulsive redosing common
Reset
a few days for acute tolerance
Effects
Positive
- Stimulation
Negative
- Teeth grinding
- Jaw clenching
- Increased heart rate
- Increased blood pressure
- Nausea
- Temperature regulation suppression
- Pupil dilation
- Vasoconstriction
- Difficulty urinating
Positive
- Cognitive euphoria
- Wakefulness
- Alertness enhancement
- Euphoria
- Motivation enhancement
Negative
- Compulsive redosing
- Anxiety
- Talkativeness
- Time distortion
- Thought acceleration
Positive
- Increased music appreciation
- Tactile enhancement
- Increased libido
- Tracers
- Color enhancement
Negative
- Dehydration
- Light sensitivity
- Appetite suppression
- Disinhibition
- Spontaneous physical sensations