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    Cyputylone molecular structure

    Cyputylone Stats & Data

    N-cyclohexylmethylone
    NPS DataHub
    MW289.37
    FormulaC17H23NO3
    SMILESCN(C1CCCCC1)C(C)C(=O)c1ccc2OCOc2c1
    InChIKeyYKIOVTWPVRMUPN-UHFFFAOYSA-N
    Phenethylamines; Cathinones; 2020/1. Von 2-Phenethylamin abgeleitete Verbindungen; 2021/1. Von 2-Phenethylamin abgeleitete Verbindungen; 2022/1. Von 2-Phenethylamin abgeleitete Verbindungen
    Chemical Class Cathinone
    Psychoactive Class Stimulant
    Half-Life Unknown in humans (do not assume methylone-like kinetics; treat redoses cautiously due to stacking)

    Effect Profile

    Curated
    Empathogen 3.7

    Moderate stimulation, sensory enhancement, and euphoria

    Empathy / Social Openness×3
    0
    Euphoria / Mood Elevation×2
    6
    Stimulation×1
    7
    Sensory Enhancement×1
    7
    Stimulant 4.8

    Strong anxiety/jitters with moderate euphoria and stimulation, low focus

    Stimulation / Energy×3
    6
    Euphoria / Mood Lift×2
    7
    Focus / Productivity×2
    3
    Anxiety / Jitters×1
    10

    Tolerance & Pharmacokinetics

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    Half-Life
    Unknown in humans (do not assume methylone-like kinetics; treat redoses cautiously due to stacking)
    Addiction Potential
    Moderate to high. Brief peaks with residual stimulation and urge to redose are commonly reported for cathinones; binge patterns are plausible. Individuals with stimulant use disorders may find control difficult.

    Tolerance Decay

    Full tolerance 0h Half tolerance 3d Baseline ~7d

    Acute tolerance can develop within a single session, especially with redosing. Anecdotally, partial tolerance may persist for several days, similar to other serotonergic cathinones. Data quality: low/anecdotal.

    Cross-Tolerances

    other cathinones (e.g., eutylone, methylone)
    50% ●○○
    amphetamine-like stimulants
    30% ●○○

    Harm Reduction

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    Evidence base is limited. Early threads and reports describe cyputylone as relatively stimulating with modest euphoria and notable body-load (jaw tension, GI upset, vasoconstriction), particularly intranasally. Some report activity at 20–30 mg rectal and 60–120 mg oral, but potency appears inconsistent across batches and vendors, and interest has remained low in user communities. Reagent tests can rule out some expected actives but cannot confirm identity; multiple reagents and, ideally, spectrometric analysis (FTIR/GC-MS) are needed. Because many '3‑MMC/4‑MMC' or 'MDMA-like' samples are mis-sold cathinones with very different potency windows, treat unfamiliar material as unknown: test a tiny amount first, avoid same-day mixing with serotonergics, and do not chase a weak come-up with repeated redoses. During dancing/heat exposure, prefer small, regular sips of electrolyte-containing fluids (about 250–500 mL per hour) and take cooling breaks; avoid overhydration to reduce hyponatremia risk. Individuals with cardiovascular disease, hypertension, arrhythmia, seizure history, or on serotonergic/MAOI therapy should avoid cyputylone. Sleep disturbance after use is common; avoid compensating with alcohol or high benzo doses, prioritize dark/cool sleep environment, gentle nutrition, and non-pharmacologic wind-down. All durations, dosages, and effects below are provisional/anecdotal; no peer‑reviewed human pharmacokinetic data exist for this compound.

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