Deschloroetizolam is not worth buying or trying. Long time Psychonaut, pharm-enthusiast; benzo lover; eitozolam user. I bought Deschloroetizolam doing little research and basically just read the hype. I finally tried it this week in varying doses.
Deschloroetizolam
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 4 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 17 combo interactions documented
- PubChem toxicity data
- classified Tentative
- classified Research-chemical
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 4 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 17 combo interactions documented
- PubChem toxicity data
- classified Tentative
- classified Research-chemical
Aliases: Etizolam-2
Summary
Deschloroetizolam is a short-acting psychoactive substance of the thienodiazepine class which has been shown to produce depressant, anxiolytic, sedative, hypnotic, muscle relaxant, anticonvulsant and amnesic effects. Deschloroetizolam, like benzodiazepines, binds to modulatory sites on the GABA receptors. Deschloroetizolam is closely related to etizolam (Etilaam), triazolam (Halcion), and alprazolam (Xanax).
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 2-4mg | 4-6mg | 6-12mg | 12mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 15-30 min | 30-60 min | 3-4 hrs | 3-4 hrs | 8-10 hrs |
Effect Profile
4 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Benzodiazepine
8.0
Intense
8/10
Strong anxiolysis and euphoria with mild sedation and cognitive impairment
Anxiolysis
×3
10
anxiety suppression
anxiolytic
muscle relaxation
muscle relaxant
emotion suppression
Sedation / Relaxation
×2
5
sedation
muscle relaxation
Motor / Cognitive Impairment
×1
4
amnesia
delusions of sobriety
Euphoria / Mood Lift
×1
10
cognitive euphoria
physical euphoria
disinhibition
Based on reports from:
Tolerance
Build-up
develops over 1–4 weeks of daily use; hypnotic tolerance faster than anxiolytic tolerance
Reset
weeks to months depending on half-life and duration of use; taper recommended
Tolerance Decay
Full tolerance
7d
Half tolerance
14d
Baseline
~30d
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Tolerance to sedation/anxiolysis builds within days of regular use and decays slowly over weeks; figures are heuristic and derived from benzodiazepine class data and community experience rather than DCE-specific trials.
Cross-Tolerances
Effects
Aggregated from 4 Erowid experience reports
Positive Effects 1
Anxiety Suppression
75.0%
70%
Adverse Effects 0
Combinations
Cross-Check Deschloroetizolam with another substanceCommunity Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.
Erowid 3 reports 2 neutral 1 cautionary visit
Deschloroetizolam 1st Time I have long and extensive experience with benzos, prescription ones and also from the research chemicals category, such as deschloroetizolam. I had a hard day and sleepless night before yesterday and not only my usual Xanax or pyrazolam were helping.
History: No benzo tolerance. I usually use them for around 6 months on and then 6 months off. I suffer from social anxiety and depression. Tablets were small 5mg hot pink coloured. Very pleasurable headspace starts about 45 minutes after ingesting 5mg.
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