I injected it into my left arm a few days ago. My entire arm actually FELL OFF It rotted so bad, I had to rush to the hospital but on the way over to the hospital it fell off!!!! I got to the ER and I walked in carrying my left arm.
Desomorphine
Well-documented
Well-documented
Multiple authoritative sources agree on dosing and effects.
- 5 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 19 combo interactions documented
- toxicity data (PsychonautWiki)
- classified Research-chemical
Well-documented
Multiple authoritative sources agree on dosing and effects.
- 5 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 19 combo interactions documented
- toxicity data (PsychonautWiki)
- classified Research-chemical
Aliases: Krok, Croc, Krokodil, Permonid, Crocodile
Summary
Desomorphine (also known as Dihydrodesoxymorphine) is an opioid substance of the morphinan chemical class that produces analgesic, muscle-relaxing, sedative, and euphoric effects when administered. It is a structural analog of morphine and the psychoactive component of the mixture known as Krokodil (also known as Crocodile, Krok, or Croc). Developed by Roche in the 1930s, desomorphine first saw use in Switzerland under the trade name Permonid.
Dose Information
Dose basis. Desomorphine is roughly 8-10 times the potency of morphine. The oral figures above are community-derived, not clinical. An earlier version of this page served morphineβs ladder verbatim β doses roughly ten times too high β corrected 7 August 2026. Illicitly produced desomorphine ("krokodil") additionally carries severe tissue injury from synthesis residues that has nothing to do with the dose.
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 2-5mg | 5-10mg | 10-15mg | 15mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 10-20 min | - | 0.5-2 hrs | 1-2 hrs | 1.67-4.33 hrs |
| Intravenous | 36 sec | 2-5 min | 30-90 min | 1-2 hrs | 1.54-3.59 hrs |
| Insufflated | 5-10 min | 10-20 min | 0.5-2 hrs | 1-2 hrs | 1.75-4.5 hrs |
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Opioid
6.6
Strong+
7/10
Strong euphoria with moderate itching/nausea, mild pain relief and sedation
Euphoria / Warmth
×3
10
physical euphoria
cognitive euphoria
euphoria
mood lift
Analgesia
×2
4
analgesia
Sedation / Relaxation
×1
4
sedation
dream potentiation
Itching / Nausea
×1
6
nausea
constipation
Based on reports from:
Add missing routes to PsychonautWiki Journal
The PsychonautWiki Journal app already has Desomorphine, but its built-in entry only covers Oral. Here are the other routes we have data for. You can't edit a built-in substance, but you can add a Custom Unit for any of these routes to log it.
⬇ Download import file
Import this file as custom substances
and you get "Desomorphine (Substance Search)" with every
route's full dose ladder and timeline, no typing. Works on iOS and
Android (v15+); the format is confirmed by the app's
developer. The manual values below work for older
versions.
Dose & duration (reference)
Desomorphine: routes the PsychonautWiki Journal app is missing Source: SubstanceSearch (substancesearch.com) Intravenous dose (mg): threshold β0.25 Insufflated dose (mg): threshold β1 Intravenous duration: onset 36s Β· come-up 2-5m Β· peak 0.5-1.5h Β· offset 1-2h Β· total 1.54-3.59h Β· after-effects 6-12h Insufflated duration: onset 5-10m Β· come-up 10-20m Β· peak 0.5-2h Β· offset 1-2h Β· total 1.75-4.5h Β· after-effects 6-12h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Custom Units carry a single dose per route, so the full ranges live in the reference above. A route's suggested dose is the midpoint of its common range. Ranges are harm-reduction guidance, not a prescription.
Tolerance
Build-up
develops within days of regular use; analgesic tolerance faster than respiratory depression tolerance
Reset
7β14 days for partial reset; full reset may take weeks β tolerance loss greatly increases overdose risk
Tolerance Decay
Full tolerance
3d
Half tolerance
5d
Baseline
~35d
Acute tolerance: develops within a single session β the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Pattern inferred from opioid class data and community reports: fast tolerance buildup with daily/frequent redosing; partial reversal over 1β2 weeks; nearβbaseline in ~3β4 weeks for many, but longer after heavy/chronic use. Data quality limited; individual variability is high.
Cross-Tolerances
Effects
Positive
- Physical euphoria
- Analgesia
- Anxiolysis
- Cough suppression
Negative
- Respiratory depression
- Skin flushing
- Nausea
- Sedation
- Itchiness
- Miosis
- Difficulty urinating
Positive
- Cognitive euphoria
- Dream potentiation
- Alertness enhancement
- Euphoria
- Mood lift
- Anxiety suppression
Negative
- Constipation
- Compulsive redosing
- Dizziness
- Talkativeness
Negative
- Double vision
- Decreased libido
- Light sensitivity
- Appetite suppression
- Cognitive dysphoria
- Internal hallucination
- Dulled perception
- Internal hallucinations
Combinations
Cross-Check Desomorphine with another substanceCommunity Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.
Bluelight 1 thread 1 cautionary visit
Desomorphine's nerd page
Pharmacology, chemical data, effect profiles, and more
→
Helpful Links
Report an issue or suggest an edit
Spotted incorrect or dangerous information, have a correction, a new study, or a useful addition for Desomorphine? Let us know. Reports are reviewed by moderators — this is not posted publicly.