I injected it into my left arm a few days ago. My entire arm actually FELL OFF It rotted so bad, I had to rush to the hospital but on the way over to the hospital it fell off!!!! I got to the ER and I walked in carrying my left arm.
Desomorphine
Well-documented
Well-documented
Multiple authoritative sources agree on dosing and effects.
- 5 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 19 combo interactions documented
- PubChem toxicity data
- classified Research-chemical
Well-documented
Multiple authoritative sources agree on dosing and effects.
- 5 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 19 combo interactions documented
- PubChem toxicity data
- classified Research-chemical
Aliases: Krok, Croc, Krokodil, Permonid, Crocodile
Summary
Desomorphine (also known as Dihydrodesoxymorphine) is an opioid substance of the morphinan chemical class that produces analgesic, muscle-relaxing, sedative, and euphoric effects when administered. It is a structural analog of morphine and the psychoactive component of the mixture known as Krokodil (also known as Crocodile, Krok, or Croc). Developed by Roche in the 1930s, desomorphine first saw use in Switzerland under the trade name Permonid.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 10-15mg | 15-20mg | 20-30mg | 30mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset |
|---|---|---|---|---|
| Oral | 10-20 min | - | 0.5-2 hrs | 1-2 hrs |
| Intravenous | 1 min | 2-5 min | 30-90 min | 1-2 hrs |
| Insufflated | 5-10 min | 10-20 min | 0.5-2 hrs | 1-2 hrs |
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Opioid
6.6
Strong+
7/10
Strong euphoria with moderate itching/nausea, mild pain relief and sedation
Euphoria / Warmth
×3
10
physical euphoria
cognitive euphoria
euphoria
mood lift
Analgesia
×2
4
analgesia
Sedation / Relaxation
×1
4
sedation
dream potentiation
Itching / Nausea
×1
6
nausea
constipation
Based on reports from:
Tolerance
Build-up
develops within days of regular use; analgesic tolerance faster than respiratory depression tolerance
Reset
7โ14 days for partial reset; full reset may take weeks โ tolerance loss greatly increases overdose risk
Tolerance Decay
Full tolerance
3d
Half tolerance
5d
Baseline
~35d
Acute tolerance: develops within a single session โ the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Pattern inferred from opioid class data and community reports: fast tolerance buildup with daily/frequent redosing; partial reversal over 1โ2 weeks; nearโbaseline in ~3โ4 weeks for many, but longer after heavy/chronic use. Data quality limited; individual variability is high.
Cross-Tolerances
Effects
Positive
- Physical euphoria
- Analgesia
- Anxiolysis
- Cough suppression
Negative
- Respiratory depression
- Skin flushing
- Nausea
- Sedation
- Itchiness
- Miosis
- Difficulty urinating
Positive
- Cognitive euphoria
- Dream potentiation
- Alertness enhancement
- Euphoria
- Mood lift
- Anxiety suppression
Negative
- Constipation
- Compulsive redosing
- Dizziness
- Talkativeness
Negative
- Double vision
- Decreased libido
- Light sensitivity
- Appetite suppression
- Decreased Libido
- Appetite Suppression
- Cognitive dysphoria
- Internal hallucination
- Dulled perception
- Internal hallucinations
Combinations
Cross-Check Desomorphine with another substanceCommunity Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.
Bluelight 1 thread 1 cautionary visit
Desomorphine's nerd page
Pharmacology, chemical data, effect profiles, and more
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Helpful Links
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