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    Dexedrine Encyclopedic
    Encyclopedic
    Typical encyclopedia coverage. Cross-reference for important decisions.
    • 2 corroborating sources
    • 1 ROA with full dose ladder
    • duration data present

    Aliases: dextroamphetamine, dexamfetamine

    Summary PsychonautWiki

    Dextroamphetamine (also known as Dexamphetamine, D-Amphetamine, Dex, Dexies, or by brand names including Adderall, Attentin, Dexedrine) is a stimulant substance and the right-handed enantiomer of amphetamine. Dextroamphetamine is the more potent enantiomer of the two, but the effects are also slightly different in character. The small difference in affinity affects the mechanism resulting in a more mentally focused stimulation rather than physical, thus creating a stimulant that is more fit as a therapeutic drug rather than a recreational one.

    Dose Information TripSit

    ROA Light Common Strong Heavy
    Oral 5-10mg 10-20mg 20-30mg 30mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TripSit

    ROA Onset Peak Offset After Effects Total
    Oral 20-60 min 3-6 hrs 2-3 hrs 2-24 hrs 3-6 hrs

    Import into PsychonautWiki Journal

    The PsychonautWiki Journal app includes Dexedrine, but its built-in data can be thinner than ours. Importing this file adds a separate "Dexedrine (Substance Search)" custom substance with our dose ranges, durations and tolerance, so you can log against whichever you prefer.

    ⬇ Download import file Import this file as custom substances and you get "Dexedrine (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer.

    Ranges are harm-reduction guidance, not a prescription.

    Tolerance

    Build-up develops over days to weeks of regular use
    Reset 3–7 days for acute tolerance; longer for full reset

    Tolerance Decay

    Half tolerance 3d Baseline ~18d

    Operational guidance: with repeated use across days, noticeable tolerance to the desired effects develops rapidly; multi‑week breaks restore sensitivity. This aligns with clinical and community observations.

    Effects Erowid

    Aggregated from 18 Erowid experience reports

    Positive Effects 7

    Stimulation 55.6% 70%
    Euphoria 50.0% 70%
    Music Enhancement 44.4% 70%
    Focus Enhancement 33.3% 70%
    Color Enhancement 16.7% 70%
    Tactile Enhancement 16.7% 70%
    Creativity Enhancement 16.7% 70%

    Adverse Effects 4

    Anxiety 44.4% 70%
    Confusion 33.3% 70%
    Jaw Clenching 22.2% 70%
    Memory Suppression 16.7% 70%

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.

    Erowid 6 reports 6 cautionary visit
    Its Nothing like a Speed High cautionary exp #7808

    I've had my share of speed. Every kid today has in this epidemic mess of mixed amphetamine salts, a.k.a Adderral, methylphenidate, a.k.a Ritalin and Concerta, and diet pills with the likes of phentermine brands like Fastin and Adipex taking ahold of the even educated, private school families i've grown to loathe.

    Pariah · Dextroamphetamine (smoked) · 2.1 mg smoked / 0.6 mg insufflated / 2.3 mg smoked
    Confidence Enhancing, not Intelligence! cautionary exp #83752

    Frequently I hear my peers deliberating on how they can score some dexedrine, adderall or ritalin. Maybe its a dick move, but although I'm on dexedrine, I tell its Strattera if they ask.

    Average student · 15 mg oral / 15 mg oral
    Three Years Gone cautionary exp #102691

    I was always ADHD. From day one. Looking back I think I would have focused more on treating my Depression than my ADHD. When I was a child I used to 'space' a lot. I had trouble following conversations, life, everything. I wasn't slow, I played chess at 6 and was quite good at it.

    InvitroCannibal · Dextroamphetamine · 80 mg oral
    Jaw Clenching All Nighter cautionary exp #4628

    Amphetamines are a wonderful and awful drug at the same time. My experience of taking it left me with mixed feelings. I took 60 mg of dexedrine pills. at around 6:30 p.m. I was going to a bonfire dance where everyone got drunk and blazed, but I had something else is mind. speed.

    Fry · 60 mg oral
    Night of The Living Dead cautionary exp #8288

    It was sometime around midnight and I was talking to some friends on the computer. I had been particularly upset because I just broke up with my boyfriend, so I wanted something to take my mind off it. A friend of mine who sells his dexedrine perscription had given me a free sample of three pills, ten milligrams each.

    SpeedVera · 30 mg insufflated
    Speed Daemons cautionary exp #4742

    I had taken Dexies before (orally) and really thought they were great. Then me and my friend decided to find a way to get the buffer off the little balls inside the capsule. We finally just crushed them and chopped them w/ a razor. 20mg lines are the best, as 10 dosen't hit the spot, and 30mg is hard to do.

    DirtyGopher · Dextroamphetamine · 20 mg insufflated
    Bluelight 5 threads 5 neutral visit
    Dextroamphetamine First Time Enjoyable neutral

    Dexedrine - experienced - first time -- enjoyable! -> total amount ingested throughout night, spanning this post and the one below; 45mg, insuflated. -> user age 20, 165lbs, 6ft2 -> setting friend's house, now also mine, all around comfortable surroundings.

    scraped 2026-03-14
    Dextroamphetamine Moderate Exp How To Love Everything neutral

    Amphetamines - Moderate - How to Love Everything There was a brief time in my life when I got to know amphetamines very well, specifically dextroamphetamine. I aquired 20 of the 15mg Dexedrine Time Release capsules from a friend and had possibly the best week of my life. This is my story.

    scraped 2026-03-14
    Dextroamphetamine Strong Bee Sting Impending Doom A Story Of Anaphylaxis neutral

    Impending Doom T+0: 12mg dextroamphetamine, 80mg caffeine T+2.5: 7mg dextroamphetamine T+3 : Strong Bee Sting (against my will) T+3.5 : 650mg Aspirin, 16mg codeine, 30mg caffeine, 400mg ibuprofen, 2mg diazepam T+10: 50mg diphenhydramine (Benadryl), 2mg diazepam I had planned to take my bike for a ride on a trail that s...

    scraped 2026-03-14
    Dextroamphetamine 240 Mg neutral

    My friend started this morning smoking psuedo meth. Like .2 of this N-Iso cut meth shit. That kind of woke him up and kind of made him groggy simultaneously. He took 3 20mg dextroamp pills. Within an hour he started feeling better and mildly elated. He researched various things about psychoactives and had a cigarette.

    scraped 2026-03-14

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