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    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    Dichloropane Encyclopedic
    Encyclopedic
    Typical encyclopedia coverage. Cross-reference for important decisions.
    • 4 corroborating sources
    • 3 ROAs with full dose ladders
    • duration data present
    • PubChem toxicity data
    • classified Tentative
    • classified Research-chemical

    Aliases: O-401, Rti-111

    Stimulant Research-chemical

    Summary TheDrug.Wiki TripSit PsychonautWiki

    Dichloropane is a novel research chemical with very limited human use history since its appearance around 2010. Due to structural similarity to cocaine, it may carry similar cardiovascular risks including potential for sudden cardiac death at high doses and long-term cardiomyopathy. Regular insufflation can severely damage nasal tissue, causing loss of smell, nosebleeds, and chronic nasal problems.

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Insufflated 10-20mg 20-40mg 40-60mg 60mg+
    Oral 10-15mg 15-30mg 30-50mg 50mg+
    Smoked 2.5-7.5mg 7.5-20mg 20-50mg 50mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects
    Insufflated 5-15 min 15-30 min 60-90 min 60-90 min 1-6 hrs
    Oral 10-30 min 30-60 min 60-90 min 60-90 min 1-6 hrs
    Smoked 15-30 min 30-60 min 60-90 min 60-90 min 1-6 hrs

    Effect Profile

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Stimulant 5.2
    Moderate+ 5/10

    Strong anxiety/jitters with moderate focus and stimulation, mild euphoria

    Stimulation / Energy ×3
    6
    stimulation mental stimulation alertness enhancement
    Euphoria / Mood Lift ×2
    5
    cognitive euphoria motivation enhancement
    Focus / Productivity ×2
    7
    focus enhancement thought acceleration motivation enhancement
    ⚠ Anxiety / Jitters ×1
    10
    anxiety teeth grinding increased heart rate tachycardia vasoconstriction
    Based on reports from:
    Erowid Experience Reports PsychonautWiki Dichloropane
    View methodology →

    Tolerance

    Build-up develops over days to weeks of regular use
    Reset 3–7 days for acute tolerance; longer for full reset

    Tolerance Decay

    Full tolerance 1d Half tolerance 10d Baseline ~18d

    Effects TheDrug.Wiki

    Positive
    • Mental Stimulation
    • Stimulation
    Negative
    • Teeth Grinding
    • Vasoconstriction
    • Increased Heart Rate
    • Increased heart rate
    • Dry Mouth
    • Insomnia
    • Tachycardia
    • Diarrhea
    Positive
    • Focus Enhancement
    • Cognitive Euphoria
    • Increased Sociability
    • Motivation Enhancement
    • Alertness enhancement
    Negative
    • Anxiety
    • Protracted Comedown
    • Constipation
    Neutral
    • Thought Acceleration
    • Talkativeness
    Positive
    • Increased Libido
    • Increased music appreciation
    • Color enhancement
    Negative
    • Appetite Suppression
    • Light sensitivity
    • Disinhibition
    • Appetite suppression
    • Dehydration
    Neutral
    • Dulled perception
    • Drifting
    Dichloropane's nerd page Pharmacology, chemical data, effect profiles, and more
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    Helpful Links

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