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    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    DMHA

    Aliases: Amidrine, Vaporpac, Octodrine, 2-aminoisoheptane, 1,5-dimethylhexylamine

    Stimulant Research-chemical

    Summary TheDrug.Wiki

    DMHA is a synthetic sympathomimetic stimulant originally developed as a nasal decongestant in the 1940s-1950s. The FDA considers DMHA an unsafe food additive and has issued warning letters to supplement manufacturers. It is banned by WADA for athletic competition and is illegal in several countries including Australia, Canada, and parts of the EU.

    Dose Information TheDrug.Wiki

    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki

    ROA Onset Comeup Peak Offset After Effects
    Oral 20-40 min 30-60 min 1-2 hrs 1-2 hrs 2-4 hrs
    Insufflated 5-15 min 15-30 min 1-2 hrs 1-2 hrs 1-3 hrs

    Effect Profile

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Stimulant 5.6
    Strong 6/10

    Strong focus and anxiety/jitters with mild stimulation and euphoria

    Stimulation / Energy ×3
    5
    stimulation increased energy
    Euphoria / Mood Lift ×2
    5
    euphoria motivation enhancement
    Focus / Productivity ×2
    10
    enhanced focus focus enhancement cognitive enhancement motivation enhancement
    ⚠ Anxiety / Jitters ×1
    10
    anxiety restlessness increased heart rate teeth grinding tachycardia vasoconstriction
    Based on reports from:
    Erowid Experience Reports PsychonautWiki DMHA
    View methodology →

    Tolerance

    Build-up develops over days to weeks of regular use
    Reset 3–7 days for acute tolerance; longer for full reset

    Tolerance Decay

    Full tolerance 14d Half tolerance 3d Baseline ~7d

    Estimates reflect stimulant-class tolerance patterns inferred from user reports; high uncertainty.

    Cross-Tolerances

    DMAA
    60%
    Caffeine
    20%

    Effects TheDrug.Wiki

    Positive
    • Stimulation
    • Increased energy
    Negative
    • Increased heart rate
    • Increased blood pressure
    • Vasoconstriction
    • Restlessness
    • Increased perspiration
    • Teeth grinding
    • Tachycardia
    • Temperature regulation suppression
    Positive
    • Enhanced focus
    • Cognitive enhancement
    • Motivation enhancement
    • Euphoria
    • Focus enhancement
    • Increased sociability
    Negative
    • Anxiety
    • Irritability
    • Cognitive fatigue
    Neutral
    • Time distortion
    Positive
    • Increased libido
    • Color enhancement
    • Increased music appreciation
    • Tactile enhancement
    Negative
    • Appetite suppression
    • Light sensitivity
    • Dehydration
    • Disinhibition
    Neutral
    • Dulled perception
    • Drifting
    DMHA's nerd page Pharmacology, chemical data, effect profiles, and more
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    Helpful Links

    📘 Experience Reports 📖 TheDrug.Wiki 📖 PsychonautWiki