DMO-PHP
Aliases: 3,4-dmohp, 3,4-dimethoxy-ฮฑ-php
Summary
Extremely limited human data. All dosage and duration figures are extrapolated from user reports and close structural analogues (ฮฑ-PHP, ฮฑ-PVP, MDPV). Functions as a potent dopamine and norepinephrine transporter inhibitor; serotonin activity appears minimal.
Dose Information
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset |
|---|---|---|---|---|
| Oral | 15-45 min | 30-60 min | 1-2.5 hrs | 1-2 hrs |
| Insufflated | 5-10 min | 10-20 min | 1-2.5 hrs | 1-2 hrs |
| Smoked | 0-2 min | 5-15 min | 1-2.5 hrs | 1-2 hrs |
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Stimulant
5.4
Moderate+
5/10
Strong euphoria and anxiety/jitters with moderate focus, low stimulation
Stimulation / Energy
×3
3
stimulation
Euphoria / Mood Lift
×2
10
physical euphoria
cognitive euphoria
euphoria
motivation enhancement
Focus / Productivity
×2
7
focus enhancement
motivation enhancement
thought acceleration
Anxiety / Jitters
×1
10
anxiety
paranoia
bruxism
increased heart rate
teeth grinding
vasoconstriction
+1 more
Based on reports from:
Tolerance
Build-up
develops over days to weeks of regular use
Reset
3โ7 days for acute; 1โ3 weeks for full reset
Tolerance Decay
Full tolerance
4d
Half tolerance
10d
Baseline
~35d
Tolerance appears to build rapidly over multiโday use (as with ฮฑโPVP/MDPV) and decays over weeks; figures are approximate and based on patterns reported for structurally similar pyrrolidinophenones rather than controlled studies. Space sessions by multiple weeks to limit escalation and psychosis risk.
Cross-Tolerances
Effects
Positive
- Stimulation
- Physical euphoria
Negative
- Bruxism
- Vasoconstriction
- Increased heart rate
- Increased blood pressure
- Sweating
- Insomnia
- Teeth grinding
- Increased perspiration
Positive
- Cognitive euphoria
- Focus enhancement
- Motivation enhancement
- Increased sociability
- Euphoria
Negative
- Compulsive redosing
- Anxiety
- Paranoia
- Cognitive fatigue
- Thought acceleration
Positive
- Increased libido
- Increased music appreciation
- Tactile enhancement
Negative
- Appetite suppression
- Light sensitivity
- Disinhibition
- Dehydration
- Appetite Suppression
- Vibrating vision
- Increase sexuality
Combinations
DMO-PHP's nerd page
Pharmacology, chemical data, effect profiles, and more
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