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    πŸ§ͺ This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    Summary TheDrug.Wiki TripSit PsychonautWiki

    DOC is an extremely potent and long-lasting psychedelic amphetamine with a steep dose-response curve. Active at sub-milligram doses with effects lasting 14-20 hours, it poses significant risks of overdose and prolonged difficult experiences. Commonly misrepresented as LSD on blotter paper.

    Perspectives

    “There is little I can say about DOC that hasn’t been said already. I am grateful that I got to experience this, grateful for the humor and grateful for the intensity and testing the limits of my endurance. DOC for me at this dose was immense, intense and domineering.”

    “I was hit with a slightly light head; the effects were quite real. I was disconnected, and somehow spacey, but this was a favorable spacey which was kind of fun. Somewhere at about the sixth hour I realized that I was beginning to drop off a bit, but six hours later yet, there was still a lot of memory. This is a long thing.”

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 1-2mg 2-4mg 4-6mg 6mg+
    Insufflated 0.25-1mg 1-2mg 2-3.5mg 3.5mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 0.75-2 hrs 1-2.5 hrs 3.5-6 hrs 3-6 hrs 6-48 hrs 10-20 hrs
    Insufflated 0-6 min 12-30 min 2-6 hrs 2-8 hrs 2-24 hrs 10-20 hrs

    Effect Profile

    148 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Validated against 83 Erowid trip reports
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 8.1
    Intense 8/10

    Strong visuals, body load, headspace, and auditory effects

    Visual Intensity ×3
    10
    color enhancement drifting tracers visual enhancement pattern recognition enhancement brightened colour
    Headspace Depth ×3
    9
    thought connectivity time distortion confusion
    Auditory Effects ×1
    8
    Body Load / Somatic Effects ×1
    10
    vasoconstriction nausea temperature regulation suppression muscle tension increased heart rate
    Stimulant 8.0
    Intense 8/10

    Strong stimulation, euphoria, and anxiety/jitters with moderate focus

    Stimulation / Energy ×3
    10
    stimulation wakefulness
    Euphoria / Mood Lift ×2
    10
    physical euphoria cognitive euphoria euphoria
    Focus / Productivity ×2
    7
    analysis enhancement
    Anxiety / Jitters ×1
    10
    anxiety restlessness increased heart rate vasoconstriction muscle tension

    Tolerance

    Build-up develops rapidly; very long duration provides natural spacing
    Reset 7–14 days for baseline

    Tolerance Decay

    Full tolerance 1d Half tolerance 7d Baseline ~14d

    Tolerance to DOC (and classic psychedelics) rises sharply after an experience and then decays over about 1–2 weeks; model and ratios are heuristic, inferred from user reports, not measured pharmacology.

    Cross-Tolerances

    LSD
    70%
    DOM
    70%
    DOB
    80%

    Effects Erowid Bluelight

    Aggregated from 83 Erowid and 65 Bluelight experience reports

    Positive Effects 69

    Stimulation 57.1% 85%
    Visual Distortions 56.4% 84%
    Color Enhancement 54.9% 85%
    Music Enhancement 40.6% 89%
    Euphoria 39.9% 88%
    Closed-Eye Visuals 32.3% 87%
    Awe 30.0% 80%
    Empathy 28.6% 80%
    Visual Trails 28.0% 84%
    Thought Acceleration 28.0% 81%
    Sedation 27.8% 85%
    Open-Eye Visuals 25.6% 89%
    Introspection 24.1% 80%
    Body High 24.1% 84%
    Auditory Effects 22.5% 82%
    Tactile Enhancement 22.5% 90%
    Morphing 22.0% 84%
    Focus Enhancement 21.8% 80%
    Geometric Imagery 18.0% 85%
    Joy 16.0% 86%

    Adverse Effects 48

    Anxiety 45.1% 76%
    Confusion 30.1% 82%
    Body Load 30.0% 77%
    Nausea 26.3% 80%
    Muscle Tension 21.8% 75%
    Dissociation 13.5% 70%
    Fear 12.0% 81%
    Insomnia 12.0% 82%
    Psychosis 10.8% 70%
    Memory Suppression 10.6% 80%
    Thought Disorganization 10.0% 78%
    Headache 9.0% 78%
    Jaw Clenching 9.0% 82%
    Increased Heart Rate 8.4% 70%
    Dysphoria 8.0% 78%
    Depersonalization 8.0% 76%
    Vomiting 8.0% 88%
    Sweating 6.0% 85%
    Frequent Urination 6.0% 80%
    Dry Mouth 6.0% 77%

    Combinations TripSit

    PiHKAL / TiHKAL Shulgin

    PiHKAL #64: DOC

    “I was hit with a slightly light head; the effects were quite real. I was disconnected, and somehow spacey, but this was a favorable spacey which was kind of fun. Somewhere at about the sixth hour I realized that I was beginning to drop off a bit, but six hours later yet, there was still a lot of memory. This is a long thing.”

    β€” Alexander Shulgin, PiHKAL (with 1.6 mg)

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