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    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    DOM

    Aliases: Stp, And peace, Tranquility, Stp (serenity, Serenity, tranquility, and peace

    Psychedelic Stimulant Research-chemical

    Summary TheDrug.Wiki Erowid TripSit PsychonautWiki

    2,5-Dimethoxy-4-methylamphetamine (also known as DOM and STP or "Serenity, Tranquility and Peace") is a lesser-known psychedelic substance of the amphetamine class. DOM is a member of the DOx family of compounds which are known for their high potency, long duration, and mixture of psychedelic and stimulant effects. It produces its effects by acting on serotonin receptors in the brain.

    Perspectives

    “Serenity, Tranquility, Peace, is certainly a fitting nickname for this substance. This is absolutely one of the most gentle psychedelics I have tasted, save for some bumpiness on the comeup.”

    “There is almost certainly an effect. Physically there is a slight dryness in the mouth, and my eyes are noticeably dilated. There is an eerie feeling overall.”

    “I suspect that for anyone who doesn't encounter these issues there is much of interest to explore. Unfortunately though, this one just doesn't seem to be for me.”

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 1-3mg 3-5mg 5-10mg 10mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 1-2 hrs 2-3 hrs 6-8 hrs 3-5 hrs 4-16 hrs 12-16 hrs

    Effect Profile

    67 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Validated against 54 Erowid trip reports
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 8.1
    Intense 8/10

    Strong visuals, body load, headspace, and auditory effects

    Visual Intensity ×3
    10
    internal hallucinations colour enhancement pattern recognition enhancement visual distortions
    Headspace Depth ×3
    9
    conceptual thinking thought connectivity time distortion
    Auditory Effects ×1
    8
    ⚠ Body Load / Somatic Effects ×1
    10
    nausea vasoconstriction increased heart rate
    Stimulant 7.2
    Strong+ 7/10

    Strong stimulation and anxiety/jitters with moderate euphoria and focus

    Stimulation / Energy ×3
    10
    stimulation wakefulness
    Euphoria / Mood Lift ×2
    7
    physical euphoria
    Focus / Productivity ×2
    7
    analysis enhancement
    ⚠ Anxiety / Jitters ×1
    10
    anxiety restlessness increased heart rate vasoconstriction
    Based on reports from:
    Effect Index The Bliss of Summer PiHKAL PiHKAL #68: DOM Bluelight Big & Dandy Thread Erowid Experience Reports PsychonautWiki DOM
    View methodology →

    Tolerance

    Build-up develops rapidly; very long duration provides natural spacing
    Reset 7–14 days for baseline

    Tolerance Decay

    Full tolerance 1d Half tolerance 7d Baseline ~14d

    Acute tolerance rises rapidly after a single dose and can persist for days; functional tolerance commonly makes redosing ineffective and mostly prolongs duration. Cross-tolerance with other classic serotonergic psychedelics is expected. Data are primarily from community reports and general psychedelic pharmacology rather than controlled trials.

    Cross-Tolerances

    LSD
    70%
    Psilocybin
    60%
    Mescaline/2C-x
    60%

    Effects Erowid Bluelight

    Aggregated from 54 Erowid and 13 Bluelight experience reports

    Positive Effects 37

    Stimulation 68.6% 83%
    Color Enhancement 58.2% 85%
    Music Enhancement 52.3% 85%
    Euphoria 41.8% 87%
    Empathy 41.8% 80%
    Focus Enhancement 33.3% 70%
    Tactile Enhancement 31.3% 85%
    Patterning 30.8% 85%
    Open-Eye Visuals 25.4% 82%
    Body High 20.9% 83%
    Closed-Eye Visuals 19.4% 90%
    Serenity 15.4% 85%
    Mystical Quality 15.4% 85%
    Geometric Imagery 15.4% 92%
    Awe 7.7% 80%
    Fractal Imagery 7.7% 85%
    Vivid Dreams 7.7% 75%
    Love 7.7% 90%
    Oneness 7.7% 80%
    Shimmering 7.7% 85%

    Adverse Effects 42

    Visual Distortions 71.7% 78%
    Anxiety 53.8% 84%
    Body Load 38.5% 88%
    Time Dilation 38.5% 79%
    Nausea 37.3% 85%
    Thought Disorganization 30.8% 80%
    Fear 23.1% 85%
    Vomiting 23.1% 83%
    Panic 23.1% 85%
    Sadness 23.1% 78%
    Insomnia 23.1% 82%
    Dysphoria 23.1% 82%
    Confusion 22.4% 75%
    Muscle Tension 16.4% 80%
    Dry Mouth 15.4% 85%
    Sweating 12.0% 85%
    Jaw Clenching 11.1% 70%
    Memory Suppression 9.3% 70%
    Increased Heart Rate 9.3% 70%
    Dizziness 7.7% 80%

    Combinations TripSit

    Trip Reports Effect Index

    The Bliss of Summer nervewing

    PiHKAL / TiHKAL Shulgin

    PiHKAL #68: DOM

    “There is almost certainly an effect. Physically there is a slight dryness in the mouth, and my eyes are noticeably dilated. There is an eerie feeling overall.”

    — Alexander Shulgin, PiHKAL (with 1.0 mg)
    DOM's nerd page Pharmacology, chemical data, effect profiles, and more
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    Helpful Links

    📘 Experience Reports 📖 TheDrug.Wiki 📖 PsychonautWiki 📖 Bluelight 📖 The Drug Users Bible