EA-3167 - Substance Search

Summary TheDrug.Wiki

Developed as an incapacitating chemical weapon; a single dose of approximately 0.2-0.3 mg intramuscularly can incapacitate for up to 10 days. Physostigmine is the preferred medical countermeasure but requires repeated administration. Volunteer studies and civilian exposures reported lingering mood and cognitive disturbances for months.

Dose Information TheDrug.Wiki

Light Common Strong Heavy

Onset, Duration & After-effects TheDrug.Wiki

ROA	Onset	Comeup	Peak	Offset	After Effects
Intramuscular	1-2 hrs	2-6 hrs	24-72 hrs	96-240 hrs	480-480 hrs

Effect Profile

Scores (1–10) curated from multiple sources:

Effect keyword matching from PsychonautWiki catalog
Weighted by importance: core (×3), major (×2), minor (×1)

Full methodology

Psychedelic 2.8

Light+ 3/10

Low visuals, body load, and headspace

Visual Intensity ×3

3

color enhancement visual distortions

Headspace Depth ×3

2

time distortion confusion

Auditory Effects ×1

0

⚠ Body Load / Somatic Effects ×1

3

tachycardia increased heart rate

Based on reports from:

Erowid Experience Reports PsychonautWiki EA-3167

Tolerance

Build-up develops rapidly after a single use

Reset 7–14 days for baseline

Tolerance Decay

Full tolerance 0h Half tolerance 21d Baseline ~30d

No systematic data on tolerance. Given the prolonged single‑exposure intoxication and absence of repeated recreational use, practical tolerance build is unlikely to be characterized. Conservatively assume at least several weeks before baseline cognition and cholinergic tone normalize after severe intoxication.