I received some fluclotizolam blotters and was extremely excited to try this new chemical out as I had not even tried a benzo in almost a entire year. I have vast experience with many different benzodiazipines and I was very curious how this one would rank next to etizolam.
Fluclotizolam
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 2 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 17 combo interactions documented
- classified Tentative
- classified Research-chemical
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 2 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 17 combo interactions documented
- classified Tentative
- classified Research-chemical
Summary
Fluclotizolam is a thienotriazolodiazepine, a benzodiazepine-class depressant that first appeared as a designer drug in 2017 despite having been first synthesized in 1979 and never marketed. It is potent, estimated at roughly 3 times stronger than etizolam, and has a comparatively short half-life that can lead to pronounced rebound insomnia and anxiety. Without medical oversight it poses serious overdose and dependence risks, particularly when combined with other depressants.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral / Sublingual | 250ug | 250-500ug | 500-750ug | 750ug+ |
| Oral | 250ug | 250-500ug | 500-750ug | 750ug+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Peak | Offset | Total |
|---|---|---|---|---|
| Oral / Sublingual | 10-30 min | 1-3 hrs | 2-4 hrs | 3-6 hrs |
| Insufflated | 5-15 min | 1-3 hrs | 2-4 hrs | 3-6 hrs |
| Rectal | 10-30 min | 1-3 hrs | 2-4 hrs | 3-6 hrs |
| Oral | 10-30 min | 3-6 hrs | - | 3-6 hrs |
Effect Profile
1 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Benzodiazepine
8.0
Intense
8/10
Strong anxiolysis and euphoria with mild sedation and cognitive impairment
Anxiolysis
×3
10
anxiolysis
anxiety suppression
anxiolytic
muscle relaxation
emotion suppression
Sedation / Relaxation
×2
5
sedation
muscle relaxation
Motor / Cognitive Impairment
×1
4
amnesia
delusions of sobriety
Euphoria / Mood Lift
×1
10
cognitive euphoria
physical euphoria
disinhibition
Based on reports from:
Tolerance
Build-up
develops over 1–4 weeks of daily use; hypnotic tolerance faster than anxiolytic tolerance
Reset
weeks to months depending on half-life and duration of use; taper recommended
Tolerance Decay
Full tolerance
5d
Half tolerance
14d
Baseline
~60d
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Rapid tolerance accumulation is typical with short-acting, high-potency benzos; intermittent spacing (≥2–3 weeks) best limits tolerance and withdrawal risk.
Cross-Tolerances
z-drugs
50%
Effects
Positive
- Anxiolysis
- Muscle relaxation
- Physical euphoria
- Anxiolytic
Negative
- Respiratory depression
- Motor impairment
- Sedation
- Sedative
- Dystaxia
- Hypnotic
Positive
- Anxiety suppression
- Cognitive euphoria
Negative
- Amnesia
- Thought deceleration
- Delusions of sobriety
- Compulsive redosing
- Delusions
- Emotion suppression
- Dizziness
- Hypnotic effects
Positive
- Increased libido
- Appetite enhancement
- Increased music appreciation
Negative
- Disinhibition
- Visual acuity suppression
- Acuity suppression
- Dehydration
- Light sensitivity
- Dulled perception
- Perception of bodily heaviness
Combinations
Cross-Check Fluclotizolam with another substanceCommunity Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.
Erowid 1 report 1 cautionary visit
Fluclotizolam's nerd page
Pharmacology, chemical data, effect profiles, and more
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Helpful Links
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