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    ๐Ÿงช This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.
    โš  Benzodiazepines can cause physical dependence with regular use. Withdrawal can be life-threatening. Never combine with opioids or alcohol.

    Fluclotizolam

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    Fluclotizolam structure

    Summary TheDrug.Wiki TripSit

    Fluclotizolam is a potent thienotriazolodiazepine approximately 3 times stronger than etizolam with a shorter half-life, leading to pronounced rebound insomnia and anxiety. First synthesized in 1979 but never marketed; emerged as a designer drug in 2017. Without medical oversight it poses serious overdose and dependence risks, particularly when combined with other depressants. Volumetric dosing from lab-weighed solutions is strongly advised due to its extreme potency and product inconsistency. Forum reports stress setting strict dosing limits and avoiding daily use to prevent tolerance and severe withdrawal.

    Dose Information TheDrug.Wiki TripSit

    ROA Light Common Strong Heavy
    Oral / Sublingual 250ug 250-500ug 500-750ug 750ug+
    Oral 250ug 250-500ug 500-750ug 750ug+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit

    ROA Onset Peak Offset After Effects Total
    Oral / Sublingual 10-30 min 1-3 hrs 2-4 hrs 1-36 hrs 180-0 min
    Insufflated 5-15 min 1-3 hrs 2-4 hrs 1-36 hrs 180-0 min
    Rectal 600-0 min 1-3 hrs 2-4 hrs 1-36 hrs 180-0 min
    Oral 10-30 min 3.0-6.0 hrs - 1.0-14.0 hrs 180-0 min

    Tolerance

    Build-up develops over 1โ€“4 weeks of daily use; hypnotic tolerance faster than anxiolytic tolerance
    Reset weeks to months depending on half-life and duration of use; taper recommended

    Effects TheDrug.Wiki

    Positive
    • Anxiolysis
    • Muscle relaxation
    • Physical euphoria
    • Anxiolytic
    Negative
    • Respiratory depression
    • Motor impairment
    Neutral
    • Sedation
    • Sedative
    • Dystaxia
    • Hypnotic
    Positive
    • Anxiety suppression
    • Cognitive euphoria
    Negative
    • Amnesia
    • Thought deceleration
    • Delusions of sobriety
    • Compulsive redosing
    • Delusions
    • Emotion suppression
    • Dizziness
    Neutral
    • Hypnotic effects
    Positive
    • Increased libido
    • Appetite enhancement
    • Increased music appreciation
    Negative
    • Disinhibition
    • Visual acuity suppression
    • Acuity suppression
    • Dehydration
    • Light sensitivity
    Neutral
    • Dulled perception
    • Perception of bodily heaviness

    Combinations TripSit

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