Flutoprazepam
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 2 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 17 combo interactions documented
- 2 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 17 combo interactions documented
Aliases: Restas, Kb-509
Summary
Flutoprazepam is an extremely long-acting benzodiazepine primarily used in Japan for severe insomnia and as an anticonvulsant. It is approximately 4 times more potent than diazepam by weight. The extremely long duration is due to its active metabolite norflurazepam (90 hour half-life), which causes significant accumulation and next-day sedation.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 0.5-1mg | 1.5-3mg | 3-5mg | 5mg+ |
Benzo Equivalence Calculator
| Substance | Equivalent Dose | Potency |
|---|
⚠ These are approximate equivalences for educational and cross-tapering reference. Individual response, tolerance, and half-life differences mean actual equivalence varies. Always consult a healthcare provider for tapering guidance.
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Total |
|---|---|---|---|---|
| Oral | 30-90 min | 1-2 hrs | 2-12 hrs | 12-16 hrs |
Effect Profile
1 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong anxiolysis, euphoria, and cognitive impairment with mild sedation
Add to PsychonautWiki Journal
The PsychonautWiki Journal logging app doesn't include every substance. To track Flutoprazepam there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:
Flutoprazepam Source: SubstanceSearch (substancesearch.com) Oral dose (mg): light 0.5-1 · common 1.5-3 · strong 3-5 · heavy 5+ Oral duration: onset 0.5-1.5h · come-up 1-2h · peak 2-12h · total 12-16h · after-effects 24-36h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 2.25 mg (Oral).
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Benzodiazepine tolerance builds with frequent exposure (days–weeks) and decays slowly (weeks). Cross-tolerance exists across most GABA-A positive allosteric modulators. Figures are approximate and largely based on clinical practice patterns and community experience rather than controlled trials for this specific drug.
Cross-Tolerances
Effects
- Muscle relaxation
- Physical euphoria
- Anxiolytic
- Muscle Relaxant
- Respiratory depression
- Motor impairment
- Sedation
- Sedative
- Dystaxia
- Hypnotic
- Anxiety suppression
- Cognitive euphoria
- Motor control loss
- Amnesia
- Emotion suppression
- Delusions of sobriety
- Dream suppression
- Thought deceleration
- Dizziness
- Compulsive redosing
- Increased libido
- Appetite enhancement
- Disinhibition
- Acuity suppression
- Visual acuity suppression
- Decreased Libido
- Double vision
- Dulled perception
- Perception of bodily heaviness
Combinations
Cross-Check Flutoprazepam with another substanceHelpful Links
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