Flutoprazepam
Aliases: Restas, Kb-509
Summary
Flutoprazepam is an extremely long-acting benzodiazepine primarily used in Japan for severe insomnia and as an anticonvulsant. It is approximately 4 times more potent than diazepam by weight. The extremely long duration is due to its active metabolite norflurazepam (90 hour half-life), which causes significant accumulation and next-day sedation.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 0.5-1mg | 1.5-3mg | 3-5mg | 5mg+ |
Benzo Equivalence Calculator
| Substance | Equivalent Dose | Potency |
|---|
⚠ These are approximate equivalences for educational and cross-tapering reference. Individual response, tolerance, and half-life differences mean actual equivalence varies. Always consult a healthcare provider for tapering guidance.
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Total |
|---|---|---|---|---|
| Oral | 30-90 min | 1-2 hrs | 2-12 hrs | 3.5-15.5 hrs |
Effect Profile
1 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong anxiolysis, euphoria, and cognitive impairment with mild sedation
Tolerance
Tolerance Decay
Benzodiazepine tolerance builds with frequent exposure (days–weeks) and decays slowly (weeks). Cross-tolerance exists across most GABA-A positive allosteric modulators. Figures are approximate and largely based on clinical practice patterns and community experience rather than controlled trials for this specific drug.
Cross-Tolerances
Effects
- Muscle relaxation
- Physical euphoria
- Anxiolytic
- Muscle Relaxant
- Respiratory depression
- Motor impairment
- Sedation
- Sedative
- Dystaxia
- Hypnotic
- Anxiety suppression
- Cognitive euphoria
- Motor control loss
- Amnesia
- Emotion suppression
- Delusions of sobriety
- Dream suppression
- Thought deceleration
- Dizziness
- Compulsive redosing
- Increased libido
- Appetite enhancement
- Disinhibition
- Acuity suppression
- Visual acuity suppression
- Decreased Libido
- Acuity Suppression
- Double vision
- Dulled perception
- Perception of bodily heaviness