Fosazepam
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 1 source
- 1 ROA with full dose ladder
- duration data present
- 17 combo interactions documented
- dose data not in PW/TripSit (unverifiable)
- 1 source
- 1 ROA with full dose ladder
- duration data present
- 17 combo interactions documented
- dose data not in PW/TripSit (unverifiable)
Summary
Fosazepam is a water-soluble phosphate ester derivative of diazepam with approximately 10-fold lower potency (100 mg fosazepam equals 10 mg diazepam). It is a prodrug that is metabolized to desmethyldiazepam (nordiazepam), which has a very long elimination half-life of approximately 72 hours. This long-acting metabolite can cause extended sedation and accumulation with repeated dosing.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 5-10mg | 10-30mg | 30-50mg | 50mg+ |
Onset, Duration & After-effects
| ROA | Onset | Peak | Offset | Total |
|---|---|---|---|---|
| Oral | 30-60 min | 1-3 hrs | 6-12 hrs | 6-12 hrs |
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong euphoria with moderate anxiolysis and sedation, mild cognitive impairment
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Benzodiazepine tolerance can develop within 1–4 weeks of frequent/daily use and decays over weeks to months after cessation. Cross‑tolerance within the benzodiazepine class is substantial; partial cross‑tolerance with Z‑drugs is expected. Data are based on class-level observations and anecdotal reports rather than fosazepam-specific studies.
Cross-Tolerances
Effects
- Muscle relaxation
- Stimulation
- Physical Euphoria
- Motor impairment
- Nausea
- Increased heart rate
- Increased blood pressure
- Increased perspiration
- Vasoconstriction
- Sedation
- Anxiety suppression
- Wakefulness
- Cognitive Euphoria
- Amnesia
- Drowsiness
- Motor control loss
- Thought deceleration
- Emotion suppression
- Anxiety
- Time Distortion
- Increased libido
- Tactile Enhancement
- Increased Music Appreciation
- Pattern Recognition Enhancement
- Disinhibition
- Appetite suppression
- Light sensitivity
- Dulled perception
- Auditory hallucination
- Auditory distortion
Combinations
Cross-Check Fosazepam with another substanceHelpful Links
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