Summary
GABA, also known as gamma-aminobutyric acid, is the main inhibitory neurotransmitter. Drugs targeting GABA include benzodiazepines, barbiturates, alcohol and GHB/GBL.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 200-400mg | 400-800mg | 800-1600mg | 1600mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Peak |
|---|---|---|
| Oral | 15-60 min | 5-8 hrs |
Effect Profile
10 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Benzodiazepine
7.6
Intense
8/10
Strong anxiolysis and euphoria with moderate cognitive impairment, mild sedation
Anxiolysis
×3
10
anxiety suppression
anxiolytic
reduced anxiety
muscle relaxation
Sedation / Relaxation
×2
5
sedation
muscle relaxation
Motor / Cognitive Impairment
×1
7
motor control loss
amnesia
double vision
Euphoria / Mood Lift
×1
10
cognitive euphoria
euphoria
physical euphoria
disinhibition
Based on reports from:
Tolerance
Build-up
develops over 1–4 weeks of daily use; hypnotic tolerance faster than anxiolytic tolerance
Reset
weeks to months depending on half-life and duration of use; taper recommended
Tolerance Decay
Full tolerance
3d
Half tolerance
37d
Baseline
~60d
Effects
Aggregated from 10 Erowid experience reports
Positive Effects 2
Anxiety Suppression
60.0%
70%
Sedation
30.0%
70%
Adverse Effects 1
Nausea
30.0%
70%
Combinations
GABA's nerd page
Pharmacology, chemical data, effect profiles, and more
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