GABA Stats & Data
BTCSSZJGUNDROE-UHFFFAOYSA-NPharmacology
DrugBankDescription
The most common inhibitory neurotransmitter in the central nervous system.
Toxicity
PubChemCarcinogenicity
No indication of carcinogenicity to humans (not listed by IARC).
Health effects (PubChem excerpts)
Chronically high levels of GABA are associated with at least 5 inborn errors of metabolism including: D-2-Hydroxyglutaric Aciduria, 4-Hydroxybutyric Aciduria/Succinic Semialdehyde Dehydrogenase Deficiency, GABA-Transaminase Deficiency, Homocarnosinosis and Succinic semialdehyde dehydrogenase deficiency.
Effect Profile
Curated + 10 ReportsStrong anxiolysis and euphoria with moderate cognitive impairment, mild sedation
Tolerance & Pharmacokinetics
drugs.wikiTolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Experience Report Analysis
ErowidDemographics
Gender Distribution
Age Distribution
Reports Over Time
Effect Analysis
ErowidEffects aggregated from 10 experience reports (10 Erowid)
Effect Sentiment Distribution
Confidence Distribution
Positive Effects 2
Adverse Effects 1
Real-World Dose Distribution
62K DosesFrom 17 individual dose entries
Oral (n=11)
Form / Preparation
Most common forms and preparations reported