Gabapentin - Substance Search

Summary TheDrug.Wiki Erowid TripSit PsychonautWiki

Gabapentin (also known as Neurontin) is a depressant substance of the gabapentinoid class. It is a structural analog of the neurotransmitter GABA and acts by inhibiting certain calcium channels in the brain, namely α2δ subunit-containing voltage-dependent calcium channels (VGCCs). Gabapentin was originally developed to treat epilepsy and is currently FDA approved to treat postherpetic neuralgia in adults and as an adjunctive therapy in the treatment of partial onset seizures.

Dose Information TheDrug.Wiki TripSit PsychonautWiki

ROA	Light	Common	Strong	Heavy
Oral BA 27%-60%	200-900mg	900-1500mg	1500-2400mg	2400mg+

Light Common Strong Heavy

Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

ROA	Onset	Peak	Offset	After Effects	Total
Oral	0.5-2 hrs	2-3 hrs	2-4 hrs	12-12 hrs	4.5-9 hrs

Tolerance

Build-up develops over 1–2 weeks of daily use

Reset 1–2 weeks of abstinence

Tolerance Decay

Full tolerance 7d Half tolerance 3d Baseline ~14d

Tolerance to the desirable sedative/euphoric effects can appear within days to weeks of daily or near‑daily use; anecdotal reports suggest partial reversal after 3–7 days off and near‑baseline within ~2 weeks. Cross‑tolerance with pregabalin is expected due to shared α2δ subunit mechanism; exact magnitude is uncertain (estimate shown is heuristic). Data quality is limited and based largely on clinical observation plus community reports; taper if using regularly to avoid withdrawal symptoms.

Cross-Tolerances

Pregabalin

50%

Effects Erowid Bluelight

Aggregated from 178 Erowid and 31 Bluelight experience reports

Positive Effects 57

Contentment 45.2% 80%

Euphoria 43.5% 89%

Anxiety Suppression 39.3% 75%

Sedation 31.1% 83%

Stimulation 30.2% 80%

Music Enhancement 20.5% 87%

Focus Enhancement 19.1% 81%

Body High 18.6% 82%

Empathy 18.2% 80%

Sociability Enhancement 16.1% 85%

Appetite Increase 16.1% 81%

Joy 16.1% 84%

Body Load 16.1% 76%

Color Enhancement 13.4% 81%

Closed-Eye Visuals 12.9% 88%

Entity Imagery 12.9% 85%

Muscle Relaxation 12.9% 86%

Lightness 12.9% 81%

Body Temperature Change 12.9% 76%

Tactile Enhancement 12.5% 78%

Adverse Effects 24

Visual Distortions 20.6% 82%

Ataxia 16.1% 83%

Confusion 14.4% 85%

Thought Disorganization 12.9% 72%

Nausea 11.0% 78%

Headache 8.6% 75%

Memory Suppression 6.2% 70%

Seizure 5.1% 70%

Sweating 4.5% 70%

Itching 3.2% 75%

Insomnia 3.2% 80%

Music Distortion 3.2% 75%

Pressure 3.2% 80%

Tremor 3.2% 75%

Vomiting 3.2% 90%

Pareidolia 3.2% 85%

Fear 3.2% 80%

Irritability 3.2% 80%

Anger 3.2% 80%

Diarrhea 3.2% 75%

Combinations TripSit

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