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    Pregabalin

    Aliases: Lyrica, Nervalin, Pregablin

    Depressant

    Summary TheDrug.Wiki Erowid TripSit PsychonautWiki

    Pregabalin (also known as 3-isobutyl GABA and by the trade-name Lyrica) is a depressant substance of the gabapentinoid class. Pregabalin is a common prescription drug, which is typically used to treat neuropathic pain, anxiety, restless leg syndrome, and as an adjunct drug in the treatment of seizures. Pregabalin has a pharmacological profile comparable to that of gabapentin as they both share similar mechanisms of action and induce similar subjective effects.

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 50-225mg 225-600mg 600-900mg 900mg+
    Rectal 40-200mg 200-450mg 450-600mg 600mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 30-60 min 1-2 hrs 4-6 hrs 4-8 hrs 4-10 hrs 9.5-17 hrs
    Insufflated 15-30 min 0.5-2 hrs 2-3 hrs 3-5 hrs 6-12 hrs 5.8-10.5 hrs
    Rectal 12-30 min 0.5-2 hrs 2-3 hrs 3-5 hrs 6-12 hrs 5.7-10.5 hrs

    Tolerance

    Build-up develops over 1–2 weeks of daily use
    Reset 1–2 weeks of abstinence

    Tolerance Decay

    Full tolerance 3d Half tolerance 7d Baseline ~10d

    Anecdotal pattern: noticeable acute tolerance develops after 1–2 days of consecutive use; many users report minimal effects from same‑day redosing. Effects tend to recover after a week or more off. Data quality: community/anecdotal with some clinical corroboration of tolerance in long‑term therapy.

    Cross-Tolerances

    Gabapentin
    50%
    Phenibut
    30%

    Effects Erowid Bluelight

    Aggregated from 136 Erowid and 30 Bluelight experience reports

    Positive Effects 49

    Euphoria 57.2% 89%
    Anxiety Suppression 43.9% 86%
    Contentment 36.7% 83%
    Stimulation 33.1% 81%
    Sedation 27.7% 86%
    Music Enhancement 25.9% 86%
    Lightness 20.0% 79%
    Drowsiness 20.0% 88%
    Body High 18.1% 84%
    Sociability Enhancement 16.7% 80%
    Tactile Enhancement 16.2% 86%
    Visual Distortions 15.7% 78%
    Empathy 15.7% 77%
    Focus Enhancement 15.1% 85%
    Color Enhancement 14.5% 86%
    Closed-Eye Visuals 13.9% 90%
    Confusion 13.8% 88%
    Pain Relief 10.3% 91%
    Peace 10.0% 82%
    Joy 10.0% 85%

    Adverse Effects 32

    Ataxia 33.3% 86%
    Blurred Vision 26.7% 84%
    Body Load 23.3% 80%
    Dizziness 23.3% 85%
    Motor Impairment 22.9% 86%
    Dry Mouth 10.0% 78%
    Seizure 8.8% 70%
    Nausea 8.4% 72%
    Thought Acceleration 6.7% 82%
    Thought Loops 6.7% 80%
    Restlessness 6.7% 80%
    Double Vision 6.7% 95%
    Dysphoria 6.7% 85%
    Vivid Dreams 3.3% 95%
    Nightmares 3.3% 85%
    Muscle Spasm 3.3% 90%
    Fear 3.3% 85%
    Emotional Blunting 3.3% 85%
    Insomnia 3.3% 80%
    Visual Fragmentation 3.3% 80%

    Combinations TripSit

    Pill Identifiers

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    Helpful Links

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