Galantamine - Substance Search

Summary PsychonautWiki

Galantamine (also known as Nivalin, Razadyne, Razadyne ER, Reminyl, and Lycoremine) is a water soluble, reversible, competitive acetylcholinesterase inhibitor that functions as a nootropic, oneirogen, and mild dissociative substance. It is well known and used widely as a dream potentiator. Along with its oneirogenic effects, it has stimulant and nootropic effects in low doses, and has mild dissociative effects in higher doses.

Dose Information TheDrug.Wiki PsychonautWiki

ROA	Light	Common	Strong	Heavy
Oral	4-8mg	8-16mg	16-24mg	24mg+

Light Common Strong Heavy

Onset, Duration & After-effects TheDrug.Wiki PsychonautWiki

ROA	Onset	Peak	Offset	After Effects
Oral	20-60 min	1-4 hrs	4-8 hrs	24-24 hrs

Effect Profile

4 reports

Scores (1–10) curated from multiple sources:

Effect keyword matching from PsychonautWiki catalog
Weighted by importance: core (×3), major (×2), minor (×1)

Full methodology

Stimulant 3.6

Moderate 4/10

Mild stimulation with low euphoria, anxiety/jitters, and focus

Stimulation / Energy ×3

4

stimulation alertness enhancement

Euphoria / Mood Lift ×2

3

cognitive euphoria

Focus / Productivity ×2

2

memory enhancement

⚠ Anxiety / Jitters ×1

3

anxiety

Based on reports from:

Erowid Experience Reports PsychonautWiki Galantamine

Tolerance

Build-up develops with repeated use over days to weeks

Reset 2–4 weeks for noticeable reduction

Tolerance Decay

Full tolerance 0h Half tolerance 3d Baseline ~7d

Robust pharmacologic tolerance is not well documented for therapeutic use; however, community oneirogenic users often perceive reduced effect with frequent dosing and report better outcomes when spacing by 3–7 days. Data are anecdotal and confounded by sleep protocol adherence.