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    Imodium molecular structure

    Imodium Stats & Data

    Fad Lope Select Entrocalm Immodium a-d
    PubChem
    MW513.5
    FormulaC29H34Cl2N2O2
    IUPAC4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide;hydrochloride
    InChIKeyPGYPOBZJRVSMDS-UHFFFAOYSA-N
    Chemical Class medicine
    Psychoactive Class Depressant

    Pharmacology

    DrugBank
    State Solid

    Description

    A condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972) Flavin adenine dinucleotide is approved for use in Japan under the trade name Adeflavin as an ophthalmic treatment for vitamin B2 deficiency.

    Indication

    Used to treat eye diseases caused by vitamin B2 deficiency, such as keratitis and blepharitis.

    Toxicity

    PubChem DrugBank

    Liver injury risk

    No documented concern

    FDA LiverTox / DILIrank. Reflects published case reports of liver injury, not absolute risk.

    Toxicity (DrugBank)

    Oral mouse LD50 > 7000 mg/kg. Intravenous mouse LD50 589 mg/kg.

    Effect Profile

    Curated
    Opioid 6.0

    Strong euphoria with moderate itching/nausea, mild pain relief, low sedation

    Euphoria / Warmth×3
    9
    Analgesia×2
    4
    Sedation / Relaxation×1
    3
    Itching / Nausea×1
    6

    Tolerance & Pharmacokinetics

    drugs.wiki

    Tolerance Decay

    Full tolerance 1d Half tolerance 21d Baseline ~35d
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