Chemical Class
medicine
Psychoactive Class
Depressant
Pharmacology
DrugBank
State Solid
Description
A condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972) Flavin adenine dinucleotide is approved for use in Japan under the trade name Adeflavin as an ophthalmic treatment for vitamin B2 deficiency.
Toxicity
Oral mouse LD50 > 7000 mg/kg. Intravenous mouse LD50 589 mg/kg.
Indication
Used to treat eye diseases caused by vitamin B2 deficiency, such as keratitis and blepharitis.
Effect Profile
Curated
Opioid
6.0
Strong euphoria with moderate itching/nausea, mild pain relief, low sedation
Euphoria / Warmth×3
9
Analgesia×2
4
Sedation / Relaxation×1
3
Itching / Nausea×1
6
Based on reports from:
Tolerance & Pharmacokinetics
drugs.wikiTolerance Decay
Full tolerance
1d
Half tolerance
21d
Baseline
~35d