Summary
JWH-073 is a synthetic cannabinoid active in the milligram range and requires precise weighing with a milligram scale to avoid overdose. Unlike cannabis, chronic abuse of synthetic cannabinoids has been associated with multiple deaths and more dangerous side effects. Individuals with personal or family history of psychotic disorders should strictly avoid use. The substance may be carcinogenic due to its naphthalene moiety. Set and setting are important factors.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Smoked | 3-5mg | 5-10mg | 10-15mg | 15mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Peak | Offset | After Effects | Total |
|---|---|---|---|---|---|
| Smoked | 5-10 min | 60-90 min | 5-10 min | 60-90 min | 60-0 min |
Tolerance
Build-up
develops over weeks of regular use via CB1 receptor downregulation
Reset
2–4 weeks for most users; heavy users may need longer
Effects
Positive
- Spontaneous tactile sensations
- Pain relief
Negative
- Increased Heart Rate
- Seizure
- Nausea
- Increased heart rate
- Dry mouth
- Sedation
- Vasodilation
- Spontaneous bodily sensations
Positive
- Emotion enhancement
- Euphoria
- Thought connectivity
- Thought Connectivity
Negative
- Motor control loss
- Anxiety
- Paranoia
- Motor Control Loss
- Memory Suppression
- Time Distortion
Positive
- Appetite enhancement
- Colour enhancement
- Auditory enhancement
- Appetite Enhancement
- Perception of Bodily Lightness
Negative
- Dehydration
- Perception of bodily heaviness
- Changes in gravity
- Spontaneous Physical Sensations
- Changes in Felt Gravity