L-Theanine Stats & Data
Theanine
N5-ethyl-l-glutamine
Gamma-glutamylethylamide
L-gamma-glutamylethylamide
NPS DataHub
MW174.2
FormulaC7H14N2O3
CAS3081-61-6
IUPAC(2''S'')-2-Ammonio-5-(ethylamino)-5-oxopentanoate
SMILES
CCNC(=O)CCC(N)C(=O)[O-].[H+]InChIKey
DATAGRPVKZEWHA-YFKPBYRVSA-N
Chemical Class
medicine
Psychoactive Class
Stimulant
Pharmacology
DrugBankDescription
Theanine, a precursor of ethylamine, is found in green tea. It is under investigation in clinical trial NCT00291070 (Effects of L-Theanine in Boys With ADHD).
Effect Profile
Curated + 12 Reports
Stimulant
5.9
Strong focus with mild euphoria, low stimulation and anxiety/jitters
Stimulation / Energy×3
3
Euphoria / Mood Lift×2
5
Focus / Productivity×2
10
Anxiety / Jitters×1
2
Based on reports from:
Tolerance & Pharmacokinetics
drugs.wikiTolerance Decay
Full tolerance
1h
Half tolerance
10d
Baseline
~14d
Experience Report Analysis
Erowid
12
Reports
2001–2020
Date Range
11
With Age Data
8
Effects Detected
Demographics
Gender Distribution
Age Distribution
Reports Over Time
Effect Analysis
ErowidEffects aggregated from 12 experience reports (12 Erowid)
12
Reports
8
Effects Detected
5
Positive
1
Adverse
2
Neutral
Effect Sentiment Distribution
Confidence Distribution
Positive Effects 5
Stimulation
66.7%
70%
Focus Enhancement
50.0%
70%
Euphoria
41.7%
70%
Music Enhancement
25.0%
70%
Tactile Enhancement
25.0%
70%
Adverse Effects 1
Anxiety
83.3%
70%
Real-World Dose Distribution
62K DosesFrom 442 individual dose entries
Oral (n=431)
Median: 400.0mg
25th: 400.0mg
75th: 400.0mg
90th: 500.0mg
mg/kg median: 2.893
mg/kg 75th: 7.249
Form / Preparation
Most common forms and preparations reported