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    L-Tyrosine Limited data
    Limited data
    Sparse data. Doses and effects may be unreliable or untested.
    • 2 corroborating sources
    • 1 ROA with full dose ladder
    • duration data present
    • toxicity data (PsychonautWiki, PubChem)
    • dose data not in PW/TripSit (unverifiable)
    • dose ladder unverifiable and undisclosed — capped

    Aliases: L-tyr, Tyrosine, 4-hydroxyphenylalanine

    Summary PsychonautWiki

    Tyrosine (also known as L-Tyrosine and 4-hydroxyphenylalanine) is a non-essential amino acid that serves a precursor to dopamine, adrenaline and norepinephrine in the human body. As a supplement, it is reported to act as a mild stimulant. It is also one of the 22 amino acids that are used by cells to synthesize proteins and is abundant in many high-protein foods, such as chicken, turkey, fish, cottage cheese, cheese, yogurt, almonds, milk, avocados, bananas, peanuts, pumpkin seeds, sesame seeds and soy products.

    Dose Information dose.wiki PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 500-1000mg 1000-2000mg 2000-3000mg 3000mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects dose.wiki PsychonautWiki

    ROA Onset Peak Offset After Effects Total
    Oral 30-90 min 1-3 hrs 1-2 hrs 6-12 hrs 2.5-6.5 hrs

    Effect Profile

    14 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Stimulant 7.4
    Strong+ 7/10

    Strong focus with moderate stimulation, mild euphoria, low anxiety/jitters

    Stimulation / Energy ×3
    7
    stimulation stamina enhancement wakefulness
    Euphoria / Mood Lift ×2
    5
    cognitive euphoria motivation enhancement
    Focus / Productivity ×2
    10
    focus enhancement analysis enhancement memory enhancement motivation enhancement thought acceleration
    Anxiety / Jitters ×1
    2
    increased heart rate
    Based on reports from:

    Import into PsychonautWiki Journal

    The PsychonautWiki Journal app includes L-Tyrosine, but its built-in data can be thinner than ours. Importing this file adds a separate "L-Tyrosine (Substance Search)" custom substance with our dose ranges, durations and tolerance, so you can log against whichever you prefer.

    ⬇ Download import file Import this file as custom substances and you get "L-Tyrosine (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer.

    Ranges are harm-reduction guidance, not a prescription.

    Tolerance

    Build-up after repeated and frequent usage
    Reset 14 days

    Tolerance Decay

    Full tolerance 1h Half tolerance 10d Baseline ~14d

    Effects Erowid

    Aggregated from 14 Erowid experience reports

    Positive Effects 3

    Stimulation 78.6% 70%
    Focus Enhancement 42.9% 70%
    Tactile Enhancement 21.4% 70%

    Adverse Effects 2

    Anxiety 28.6% 70%
    Increased Heart Rate 28.6% 70%

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.

    Erowid 5 reports 4 neutral 1 cautionary visit
    Totally Underrated cautionary exp #19338

    So many of us have tried the speed like drugs, and found the high useful and pleasurable. However, the illegality, expense and health effects deter, rightly, most people from relying on these drugs too often. Upon ingesting 1/4-1/3 or so of a teaspoon (~600mg-1200mg) of tyrosine powder, an almost immediate 'up' comes.

    Dr Smooth · Tyrosine · 0.25 tsp oral
    Three Experiences neutral exp #54596

    I bought a bottle of Tyrosine, 100 pills of 500mg each, for about $15. Here are the three experiences Experience one: at 500mg I took one pill to test out the strength of the dosage, then went and worked out with my usual calisthenics routine in the park along with my friend J.

    Dead · Tyrosine · 500 mg oral / 3000 mg oral / 1000 mg oral
    A Bit Overrated neutral exp #80892

    I usually take 650mg/day to reduce fatigue, and make me more productive at work. It really increase alertness, but it can't push me more, when my mind gets tired (not good for staying up all night and learning for an exam).

    Forseti · Tyrosine · 650 mg oral
    OTC Focus neutral exp #93414

    I have been struggling with focus in my university courses for over a year now since I began taking oxycodone for a herniated disc. 5:30pm:Starting with 2x 1000mg tablets (playing halo with friends) 5:45pm: No subjective effects 6:00pm: Increase in heart rate (not enough to cause concern) 6:20pm: Completely 'dialed in'...

    AxeGuy · Tyrosine · 2 g oral / smoked
    Not Bad neutral exp #66105

    I heard about the stimulant and potentially perception altering effects of tyrosine, so I figured I'd give it a shot. I bought a bottle for about 10 bucks and it had 60 pills at 1000mg each. I popped one and went ahead and started my training regimen that day.

    Kai's Journey · Tyrosine · 1000 mg oral

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