I obtained a 50mg capsule of Vyvanse, and decided to split it, since I really have no focus problems at all I just wanted to see what it was like. I had tried 20mg before (I tried to split it evenly but I failed) and it was very pleasant, so I was expecting the same experience, more or less.
Lisdexamfetamine
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 1 source
- 1 ROA with full dose ladder
- duration data present
- 18 combo interactions documented
- PubChem toxicity data
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 1 source
- 1 ROA with full dose ladder
- duration data present
- 18 combo interactions documented
- PubChem toxicity data
Aliases: Vyvanse, Elvanse, Tyvense, Lisdextroamphetamine, lisdextroamfetamine, lisdexamphetamine
Summary
Lisdexamfetamine is a prodrug that is inactive until enzymatically converted to dextroamphetamine by red blood cells. This design provides extended-release effects lasting 10-14 hours and theoretically reduces abuse potential, as insufflation or injection does not accelerate onset. Approved for ADHD in adults and children 6+ years, and for binge eating disorder in adults.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 20-30mg | 30-50mg | 50-100mg | 100mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset |
|---|---|---|---|---|
| Oral | 1-2 hrs | 30-60 min | 3-5 hrs | 4-6 hrs |
Effect Profile
51 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Validated against 51 Erowid trip reports
- Weighted by importance: core (×3), major (×2), minor (×1)
Stimulant
8.8
Intense+
9/10
Strong stimulation, euphoria, focus, and anxiety/jitters
Stimulation / Energy
×3
10
stimulation
wakefulness
Euphoria / Mood Lift
×2
10
physical euphoria
cognitive euphoria
euphoria
motivation enhancement
Focus / Productivity
×2
10
focus enhancement
analysis enhancement
motivation enhancement
thought acceleration
Anxiety / Jitters
×1
10
anxiety
increased heart rate
Based on reports from:
Tolerance
Build-up
develops over days to weeks of regular use
Reset
3–7 days for acute; 1–3 weeks for full reset
Tolerance Decay
Full tolerance
7d
Half tolerance
14d
Baseline
~28d
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Clinical and community data indicate noticeable tolerance with repeated daily dosing within days, and partial reversal after several weeks of abstinence. Quantitative values are heuristic for harm‑reduction planning, not prescriptive dosing guidance.
Cross-Tolerances
Amphetamines
80%
Other stimulants
30%
Effects
Aggregated from 51 Erowid experience reports
Positive Effects 9
Stimulation
68.6%
70%
Focus Enhancement
62.7%
70%
Euphoria
52.9%
70%
Music Enhancement
37.3%
70%
Body High
27.5%
70%
Empathy
19.6%
70%
Tactile Enhancement
13.7%
70%
Color Enhancement
11.8%
70%
Creativity Enhancement
5.9%
70%
Adverse Effects 10
Anxiety
43.1%
70%
Nausea
19.6%
70%
Jaw Clenching
17.6%
70%
Increased Heart Rate
17.6%
70%
Confusion
17.6%
70%
Sweating
15.7%
70%
Headache
15.7%
70%
Appetite Suppression
15.7%
70%
Pupil Dilation
7.8%
70%
Memory Suppression
5.9%
70%
Combinations
Cross-Check Lisdexamfetamine with another substanceCommunity Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.
Erowid 8 reports 1 positive 5 neutral 2 cautionary visit
Background: Generally, I'm not too experienced in drugs so far. I've smoked quite a bit of weed in my life, drank a few times, snorted hydrocodone / Vicodin (not recommended), and snorted Ritalin and Adderall. The only drugs out of these that I've used repeatedly are weed and Vicodin.
Background Im a recovering addict so I havent consumed any intoxicating substances in the past 5 months. I smoked marijuana and hash habitually (multiple times a day) for the past 2 years, I have experience with psychadelics (LSD, psilocybin containing mushrooms, MDMA, and salvia dinorum), and Ive abused various p...
Midterm and Vyvanse Here is the context of this experience report. Its the first time I ever took Amphetamine. I took it because I needed to be very productive to finish a mid-term paper and I usually have a lot of trouble to concentrate on this kind of work so I figured the Vyvanse would help.
Let me begin by saying I have experimented with several drugs including weed, alcohol, ecstasy, and prescription pills (Xanax, Adderall, Ritalin, Methadone). This entry is about the prescription medication, Vyvanse. It isnt my prescription, it is my brothers.
Vyvanse, an Adderrall Alternative I have tried most things out there for ADHD, being a college student, and have a prescription for Vyvanse now. I personally think that it is one of the best to aid in any attempt to make my concentration increase.
The end of the semester again approaches. A couple 50mg Vyvanse capsules make their way into my possession because of a good friend. My past experiences with stimulants have been, on the whole, very horrific and negative.
I wanted to try lisdexamfetamine for a few reasons: Clinically, I've dealt with a hodgepodge of eating disordered behavior over the years, including binge eating disorder, and Vyvanse was recently approved to treat this. I don't meet the clinical criteria but binge often enough that it was a concern to me.
Bluelight 8 threads 7 neutral 1 cautionary visit
(I'm new to the site and looking for advice on where to but this thread which is about my small amount of experience of using Vyvanse recreational and some questions.) [h=2]tl;dr short one: I'm confused that Vyvanse makes me feel drunk and not focus when it should, why? what are the mental and physical side effects of...
I have previously taken adderall and ritalin every couple months or so when I have the ability to acquire them I absolutely love taking them at school due to the obvious side effects of increased sociability and concentration.
Hello, thought I should share my trip report with you all because it wasn't what I expected! I will give you a little background info. I am prescribed as follows- Elvanse 50mg (ADHD), Quetiapine 100mg (Anxiety), Promethazine 50mg (Sleep). All medications usually taken daily and as prescribed.
Ok, this is my first trip report so lets give it a try. Im probably 6ft 220Lbs pretty muscular Two days ago my friend calls me up asking if i knew where to get some adderall. Right off the top of my head i knew a guy that could hook me up so i gave him a call. He told me he could give me 4 vyvanse 70mg.
Decided to do a test on how much I may tweak by adding a pill a week. In this report I will be using 70mg vyvanse each week and adding more 1 per week. I will not be using vyvanse during the week for tolerance issues. 1st Week, Dosage : 70mg. Prescription based.
Hey, I'm new to Bluelight so I'd love some feedback on this report as this is my first on this forum. My friend Joe had heard on another forum that one can bypass the "extended release" portion of vyvanse by cleaving the l-lysine portion of the molecule off with an enzyme supplement containing Trypsin.
Vyanse 300mg (10 x 30mg capsules in one go). Experienced: Make sure your mind is in a good place I got to say I'm quite used to amphetamines of all sorts and I'm almost always able to never over do it as dosage wise, but this time I didn't.
Ok so this is my first post, so please don't judge any mistakes I make. So this was my first time trying an amphetamine, so I tried vyvanse. Normally I spend a long time studying a drug before I use it, been like that since I overdosed on pills and went to the hospital when I first got into drugs.
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