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    Disclaimer
    Benzodiazepines can cause physical dependence with regular use. Withdrawal can be life-threatening. Never combine with opioids or alcohol.

    Loprazolam Encyclopedic
    Encyclopedic
    Typical encyclopedia coverage. Cross-reference for important decisions.
    • 1 source
    • 1 ROA with full dose ladder
    • duration data present
    • 17 combo interactions documented
    • PubChem toxicity data

    Aliases: Dormonoct

    Summary TripSit

    Is an Imidazolobenzidazepine derivative that has all the classic benzodiazepine effects. Is usually only prescribed for a short amount of time for insomnia.

    Dose Information TripSit

    ROA Light Common Strong Heavy
    Oral 0.25-0.5mg 0.5-1.5mg 1.5-3mg 3mg+
    Light Common Strong Heavy

    Benzo Equivalence Calculator

    mg
    mg Loprazolam
    =
    mg Diazepam

    ⚠ These are approximate equivalences for educational and cross-tapering reference. Individual response, tolerance, and half-life differences mean actual equivalence varies. Always consult a healthcare provider for tapering guidance.

    Onset, Duration & After-effects TripSit

    ROA Onset Peak After Effects Total
    Oral 30-50 min 6-10 hrs 1-8 hrs 6-10 hrs

    Effect Profile

    class estimate

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • No reports exist for this substance. Its effect list is the one shared by 3 other substances of the same class, so the scores below describe the class, not this compound.
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Benzodiazepine 7.6
    Intense 8/10

    Strong euphoria and anxiolysis with mild sedation, low cognitive impairment

    Anxiolysis ×3
    8
    anxiety suppression reduced anxiety muscle relaxation
    Sedation / Relaxation ×2
    5
    sedation muscle relaxation
    Motor / Cognitive Impairment ×1
    1
    double vision
    Euphoria / Mood Lift ×1
    10
    cognitive euphoria euphoria physical euphoria disinhibition

    Add to PsychonautWiki Journal

    The PsychonautWiki Journal logging app doesn't include every substance. To track Loprazolam there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:

    ⬇ Download import file Import this file as custom substances and you get "Loprazolam (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer. The manual values below work for older versions.
    Name
    Loprazolam
    Unit
    mg
    Description
    Loprazolam
    Source: SubstanceSearch (substancesearch.com)
    
    Oral dose (mg): light 0.25-0.5 · common 0.5-1.5 · strong 1.5-3 · heavy 3+
    
    Oral duration: onset 30-50m · peak 6-10h · total 6-10h · after-effects 1-8h
    
    Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 1 mg (Oral).

    The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.

    Tolerance

    Build-up develops over 1–4 weeks of daily use; hypnotic tolerance faster than anxiolytic tolerance
    Reset weeks to months depending on half-life and duration of use; taper recommended

    Tolerance Decay

    Full tolerance 3d Half tolerance 37d Baseline ~60d

    Effects

    Positive
    • Stimulation
    • Physical euphoria
    • Muscle relaxation
    Negative
    • Motor impairment
    • Increased heart rate
    • Nausea
    • Respiratory depression
    • Vasoconstriction
    • Teeth grinding
    Neutral
    • Sedation
    Positive
    • Reduced anxiety
    • Cognitive euphoria
    • Euphoria
    • Anxiety suppression
    • Wakefulness
    Negative
    • Compulsive redosing
    • Anxiety
    • Dizziness
    • Thought deceleration
    Neutral
    • Time distortion
    Positive
    • Increased music appreciation
    • Increased libido
    • Tactile enhancement
    • Color enhancement
    Negative
    • Disinhibition
    • Dehydration
    • Appetite suppression
    • Light sensitivity
    • Double vision
    Neutral
    • Dulled perception

    Combinations TripSit

    Cross-Check Loprazolam with another substance

    Helpful Links