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    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    MAL

    Aliases: Methallylescaline

    Psychedelic Research-chemical

    Summary TheDrug.Wiki TripSit PsychonautWiki

    Methallylescaline is a synthetic mescaline analog first synthesized by Alexander Shulgin. It has an unusually steep dose-response curve where small dosage changes can dramatically alter the experience. Known for producing intense visual and tactile effects with a pronounced body load that can include nausea, muscle cramps, and difficulty urinating at higher doses.

    Perspectives

    “An interesting psychedelic with a nature of being very taut, springy, and vibrate-y. It was thin and high pitched but harmonious.”

    “Too much overload. I am surrounded with unreality. I do not choose to repeat the experiment.”

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 15-25mg 25-40mg 40-60mg 60mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 19-60 min 30-90 min 3-8 hrs 2-4 hrs 4-24 hrs 6-12 hrs

    Effect Profile

    21 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Validated against 21 Erowid trip reports
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 8.8
    Intense+ 9/10

    Strong visuals, headspace, auditory effects, and body load

    Visual Intensity ×3
    10
    internal hallucinations colour enhancement autonomous entities drifting tracers visual enhancement +7 more
    Headspace Depth ×3
    10
    conceptual thinking thought connectivity emotion enhancement perspective alterations delusions personal bias suppression +3 more
    Auditory Effects ×1
    10
    auditory distortion auditory enhancement auditory hallucinations
    ⚠ Body Load / Somatic Effects ×1
    10
    nausea muscle tension increased heart rate
    Based on reports from:
    Effect Index Another Punch in the Gut PiHKAL PiHKAL #99: MAL Bluelight Big & Dandy Thread Erowid Experience Reports PsychonautWiki MAL
    View methodology →

    Tolerance

    Build-up develops rapidly after a single use (serotonergic psychedelic)
    Reset 7–14 days for baseline

    Tolerance Decay

    Full tolerance 1d Half tolerance 3d Baseline ~14d

    Rapid tolerance develops to classical psychedelics and cross‑tolerance is well‑documented between LSD and mescaline; MAL is inferred to follow a similar 5‑HT2A‑mediated pattern. Values above are heuristic for planning intervals, not pharmacokinetic half‑life. Data quality primarily anecdotal with inference from classic literature.

    Cross-Tolerances

    LSD
    70%
    Mescaline
    70%
    2C‑x phenethylamines
    60%
    DOx phenethylamines
    60%

    Effects Erowid

    Aggregated from 21 Erowid experience reports

    Positive Effects 9

    Stimulation 76.2% 70%
    Color Enhancement 61.9% 70%
    Music Enhancement 47.6% 70%
    Body High 42.9% 70%
    Empathy 38.1% 70%
    Focus Enhancement 33.3% 70%
    Euphoria 28.6% 70%
    Introspection 28.6% 70%
    Tactile Enhancement 23.8% 70%

    Adverse Effects 9

    Nausea 81.0% 70%
    Anxiety 66.7% 70%
    Muscle Tension 42.9% 70%
    Headache 33.3% 70%
    Confusion 23.8% 70%
    Jaw Clenching 19.0% 70%
    Pupil Dilation 19.0% 70%
    Memory Suppression 19.0% 70%
    Increased Heart Rate 14.3% 70%

    Combinations TripSit

    Trip Reports Effect Index

    Another Punch in the Gut nervewing

    PiHKAL / TiHKAL Shulgin

    PiHKAL #99: MAL

    “Too much overload. I am surrounded with unreality. I do not choose to repeat the experiment.”

    — Alexander Shulgin, PiHKAL (with 45 mg)
    MAL's nerd page Pharmacology, chemical data, effect profiles, and more
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    Helpful Links

    📘 Experience Reports 📖 TheDrug.Wiki 📖 PsychonautWiki 📖 Bluelight