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    πŸ§ͺ This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    MAL Well-documented
    Well-documented
    Multiple authoritative sources agree on dosing and effects.
    • 5 corroborating sources
    • 1 ROA with full dose ladder
    • duration data present
    • 18 combo interactions documented
    • PubChem toxicity data
    • classified Research-chemical

    Aliases: Methallylescaline

    Summary TheDrug.Wiki TripSit PsychonautWiki

    Methallylescaline is a synthetic mescaline analog first synthesized by Alexander Shulgin. It has an unusually steep dose-response curve where small dosage changes can dramatically alter the experience. Known for producing intense visual and tactile effects with a pronounced body load that can include nausea, muscle cramps, and difficulty urinating at higher doses.

    Perspectives

    “An interesting psychedelic with a nature of being very taut, springy, and vibrate-y. It was thin and high pitched but harmonious.”

    “Too much overload. I am surrounded with unreality. I do not choose to repeat the experiment.”

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 15-25mg 25-40mg 40-60mg 60mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 19-60 min 30-90 min 3-8 hrs 2-4 hrs 4-24 hrs 6-12 hrs

    Effect Profile

    21 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Validated against 21 Erowid trip reports
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 8.8
    Intense+ 9/10

    Strong visuals, headspace, auditory effects, and body load

    Visual Intensity ×3
    10
    internal hallucinations colour enhancement autonomous entities drifting tracers visual enhancement +7 more
    Headspace Depth ×3
    10
    conceptual thinking thought connectivity emotion enhancement perspective alterations delusions personal bias suppression +3 more
    Auditory Effects ×1
    10
    auditory distortion auditory enhancement auditory hallucinations
    Body Load / Somatic Effects ×1
    10
    nausea muscle tension increased heart rate

    Tolerance

    Build-up develops rapidly after a single use (serotonergic psychedelic)
    Reset 7–14 days for baseline

    Tolerance Decay

    Full tolerance 1d Half tolerance 7d Baseline ~14d

    Rapid tolerance develops to classical psychedelics and cross‑tolerance is well‑documented between LSD and mescaline; MAL is inferred to follow a similar 5‑HT2A‑mediated pattern. Values above are heuristic for planning intervals, not pharmacokinetic half‑life. Data quality primarily anecdotal with inference from classic literature.

    Cross-Tolerances

    Effects Erowid

    Aggregated from 21 Erowid experience reports

    Positive Effects 9

    Stimulation 76.2% 70%
    Color Enhancement 61.9% 70%
    Music Enhancement 47.6% 70%
    Body High 42.9% 70%
    Empathy 38.1% 70%
    Focus Enhancement 33.3% 70%
    Euphoria 28.6% 70%
    Introspection 28.6% 70%
    Tactile Enhancement 23.8% 70%

    Adverse Effects 9

    Nausea 81.0% 70%
    Anxiety 66.7% 70%
    Muscle Tension 42.9% 70%
    Headache 33.3% 70%
    Confusion 23.8% 70%
    Jaw Clenching 19.0% 70%
    Pupil Dilation 19.0% 70%
    Memory Suppression 19.0% 70%
    Increased Heart Rate 14.3% 70%

    Combinations TripSit

    Cross-Check MAL with another substance

    Trip Reports Effect Index

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.

    Erowid 8 reports 7 neutral 1 cautionary visit
    Electric Neon Visual Wonderland neutral exp #109458

    Methylallylescaline - 65mg, orally I had only one prior experience with this compound, and it happened about two months prior to this experience. I've had experience with 2C-T-2, 2C-E, 2C-I, 2C-B, 25[b,c,i,g]-NBOMe, DOM, Allylescaline, and Proscaline, which are most relevant to this experience as they are mescaline ana...

    MrMoran · Methallylescaline · 65 mg oral / smoked / oral / smoked
    Long Duration, Quite Pleasant Overall neutral exp #107150

    T-05:00 :: Alcohol, Beer, 7.2% (2) T-01:30 :: Alcohol, Beer, 7.2% (1) T-01:00 :: Etizolam, 1mg T+00:00 :: Methallylescaline (MAL), 52.05mg T+16:00 :: Etizolam, 2mg T+17:00 :: Alcohol, Beer, 7.2% (1) T+18:00 :: Alcohol, Beer, 7.2% (1) I had previously prepared a solution of this in water so that I could accurately measu...

    FlowGnome · Methallylescaline · repeated oral / 1 mg oral / 52 mg oral / 2 mg oral
    A Day with MAL neutral exp #105275

    I first head of Methallylescaline, or MAL, and similar Mescaline analogues online and how relatively rare and unpopular they were. I further read a few experiences and was interested in giving the substance a try.

    A-346 · Methallylescaline · 45 mg oral
    My Body Hates Me neutral exp #107732

    T0:00-Mix powder into orange soda. There is absolutely no flavor, interestingly enough, no cringe inducing bitterness. I have mixed psychedelics with orange soda before (4-AcO-DMT and Psilocin), and the bitterness pierced through the flavor and made me cringe and shiver. I sip it.

    nervewing · Methallylescaline · 50 mg oral / smoked / smoked / smoked
    More or Less Mescaline neutral exp #105263

    Me: 140lb white male. 30 years old. Generally, my reactions to psychoactives are idiosyncratic, so I don't post them. There's not much use if you can't extrapolate from them. For instance, I react badly to cannabis and MDMA, but enjoy bufotenine and salvia.

    Pfaffed · Methallylescaline
    Beams of Light neutral exp #107907

    I had this experience while at home from college, when the air gets colder and the sun sets earlier (Sometimes I feel psychedelics can set the mood for a season).

    SirSlothSlayer · Methallylescaline · 30 mg oral / smoked
    Incredibly Nauseating with No Reward neutral exp #107717

    J: 180lb, 65mg MAL dose (capsule) M: 130lb, 45mg MAL dose (capsule) Set and Setting: Both of us were excited to try MAL for the first time. The substance was tested with Mecke, Mandeline, and Marquis and was positively tested to be Methallylescaline HCl.

    ThePhoenix · Methallylescaline · 65 mg oral
    A Trip to the Hospital cautionary exp #105249

    [Erowid Note: The dose described in this report is very high, potentially beyond Erowid's 'heavy' range, and could pose serious health risks or result in unwanted, extreme effects.

    Used2BaboutRCs · Methallylescaline · 130 mg oral
    Bluelight 4 threads 4 neutral visit
    Methylallylescaline Mal Beginner Dancing In The Wind With Mal neutral

    Hi! I'm a long time (5+ year) lurker, it's about time I posted a TR. Early 30's female, 80kg (I'm tall) Moderate psychedelic experience. I generally prefer low doses, but have experimented with 10g mushrooms and 600ug LSD once each. Counting DMT, probably ~20-25 trips.

    scraped 2026-03-14
    Mal Methylallylescaline Experienced 25mg 5mg Rectal neutral

    MAL / METHYLALLYLESCALINE - 25mg + 5mg rectal - Second time by this ROA tl;dr - I've had many good experiences with MAL. This wasn't one of them. Nor was it a bad one. It was just an inexplicable, dull, gross nothingburger.

    scraped 2026-03-14
    Mal 38 Mg Moderately Experienced How Do I Use This neutral

    My apologies in advance for a lack of a rich narrative...the trip just wasn't that interesting (at least for the external observer), and I just want to get some information on this (somewhat rare) compound out there. I am a early-30 something male weighing roughly 80 kg.

    scraped 2026-03-14
    Mal 25mg First Time More Similar To Mesaline Than Different neutral

    I noticed a lack of reports on MAL on the internet, so I wrote this one up. Me: 140lb white male. 30 years old. Generally, my reactions to psychoactives are idiosyncratic, so I don't post them. There's not much use if you can't extrapolate from them.

    scraped 2026-03-14

    Bluelight Reference Guide Bluelight

    Phenethylamines The Big & Dandy Methallylescaline (MAL) Thread

    MethylAllylEscaline (MAL) Links: Wikipedia Page PiHKAL entry Pihkal Info MAL DOSAGE: 40 - 65 mg. DURATION: 12 - 16 h. QUALITATIVE COMMENTS: (with 45 mg) Too much overload. I am sur-rounded with unreality. I do not choose to repeat the experiment. (with 45 mg) I am basically favorably impressed.

    Read full thread on Bluelight β†’

    PiHKAL / TiHKAL Shulgin

    PiHKAL #99: MAL

    “Too much overload. I am surrounded with unreality. I do not choose to repeat the experiment.”

    β€” Alexander Shulgin, PiHKAL (with 45 mg)

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