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    πŸ§ͺ This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    MAL Well-documented
    Well-documented
    Multiple authoritative sources agree on dosing and effects.
    • 5 corroborating sources
    • 1 ROA with full dose ladder
    • duration data present
    • 18 combo interactions documented
    • toxicity data (PsychonautWiki)
    • classified Research-chemical

    Aliases: Methallylescaline

    Summary dose.wiki TripSit PsychonautWiki

    Methallylescaline is a synthetic mescaline analog first synthesized by Alexander Shulgin. It has an unusually steep dose-response curve where small dosage changes can dramatically alter the experience. Known for producing intense visual and tactile effects with a pronounced body load that can include nausea, muscle cramps, and difficulty urinating at higher doses.

    Perspectives

    “Anyways, aside from this, it was an interesting psychedelic, it had a nature of being very taut, springy, and vibrate-y. It was thin and high pitched but harmonious.”

    “Too much overload. I am surrounded with unreality. I do not choose to repeat the experiment.”

    Dose Information dose.wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 15-25mg 25-40mg 40-60mg 60mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects dose.wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 19-60 min 30-90 min 3-8 hrs 2-4 hrs 4-24 hrs 6-12 hrs

    Effect Profile

    21 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Validated against 21 Erowid trip reports
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 8.8
    Intense+ 9/10

    Strong visuals, headspace, auditory effects, and body load

    Visual Intensity ×3
    10
    internal hallucinations colour enhancement autonomous entities drifting tracers visual enhancement +7 more
    Headspace Depth ×3
    10
    conceptual thinking thought connectivity emotion enhancement perspective alterations delusions personal bias suppression +3 more
    Auditory Effects ×1
    10
    auditory distortion auditory enhancement auditory hallucinations
    Body Load / Somatic Effects ×1
    10
    nausea muscle tension increased heart rate

    Import into PsychonautWiki Journal

    The PsychonautWiki Journal app includes MAL, but its built-in data can be thinner than ours. Importing this file adds a separate "MAL (Substance Search)" custom substance with our dose ranges, durations and tolerance, so you can log against whichever you prefer.

    ⬇ Download import file Import this file as custom substances and you get "MAL (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer.

    Ranges are harm-reduction guidance, not a prescription.

    Tolerance

    Build-up develops rapidly after a single use
    Reset 7–14 days for baseline

    Tolerance Decay

    Full tolerance 1d Half tolerance 7d Baseline ~14d

    Rapid tolerance develops to classical psychedelics and cross‑tolerance is well‑documented between LSD and mescaline; MAL is inferred to follow a similar 5‑HT2A‑mediated pattern. Values above are heuristic for planning intervals, not pharmacokinetic half‑life. Data quality primarily anecdotal with inference from classic literature.

    Cross-Tolerances

    Effects Erowid

    Aggregated from 21 Erowid experience reports

    Positive Effects 9

    Stimulation 76.2% 70%
    Color Enhancement 61.9% 70%
    Music Enhancement 47.6% 70%
    Body High 42.9% 70%
    Empathy 38.1% 70%
    Focus Enhancement 33.3% 70%
    Euphoria 28.6% 70%
    Introspection 28.6% 70%
    Tactile Enhancement 23.8% 70%

    Adverse Effects 9

    Nausea 81.0% 70%
    Anxiety 66.7% 70%
    Muscle Tension 42.9% 70%
    Headache 33.3% 70%
    Confusion 23.8% 70%
    Jaw Clenching 19.0% 70%
    Pupil Dilation 19.0% 70%
    Memory Suppression 19.0% 70%
    Increased Heart Rate 14.3% 70%

    Combinations

    Cross-Check MAL with another substance

    Trip Reports Effect Index

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.

    Erowid 8 reports 3 positive 1 neutral 4 cautionary visit
    Electric Neon Visual Wonderland cautionary exp #109458

    Methylallylescaline - 65mg, orally I had only one prior experience with this compound, and it happened about two months prior to this experience. I've had experience with 2C-T-2, 2C-E, 2C-I, 2C-B, 25[b,c,i,g]-NBOMe, DOM, Allylescaline, and Proscaline, which are most relevant to this experience as they are mescaline ana...

    MrMoran · Methallylescaline · 65 mg oral / smoked / oral / smoked
    Long Duration, Quite Pleasant Overall positive exp #107150

    T-05:00 :: Alcohol, Beer, 7.2% (2) T-01:30 :: Alcohol, Beer, 7.2% (1) T-01:00 :: Etizolam, 1mg T+00:00 :: Methallylescaline (MAL), 52.05mg T+16:00 :: Etizolam, 2mg T+17:00 :: Alcohol, Beer, 7.2% (1) T+18:00 :: Alcohol, Beer, 7.2% (1) I had previously prepared a solution of this in water so that I could accurately measu...

    FlowGnome · Methallylescaline · repeated oral / 1 mg oral / 52 mg oral / 2 mg oral
    A Day with MAL neutral exp #105275

    I first head of Methallylescaline, or MAL, and similar Mescaline analogues online and how relatively rare and unpopular they were. I further read a few experiences and was interested in giving the substance a try.

    A-346 · Methallylescaline · 45 mg oral
    My Body Hates Me cautionary exp #107732

    T0:00-Mix powder into orange soda. There is absolutely no flavor, interestingly enough, no cringe inducing bitterness. I have mixed psychedelics with orange soda before (4-AcO-DMT and Psilocin), and the bitterness pierced through the flavor and made me cringe and shiver. I sip it.

    nervewing · Methallylescaline · 50 mg oral / smoked / smoked / smoked
    More or Less Mescaline positive exp #105263

    Me: 140lb white male. 30 years old. Generally, my reactions to psychoactives are idiosyncratic, so I don't post them. There's not much use if you can't extrapolate from them. For instance, I react badly to cannabis and MDMA, but enjoy bufotenine and salvia.

    Pfaffed · Methallylescaline
    Beams of Light positive exp #107907

    I had this experience while at home from college, when the air gets colder and the sun sets earlier (Sometimes I feel psychedelics can set the mood for a season).

    SirSlothSlayer · Methallylescaline · 30 mg oral / smoked
    Incredibly Nauseating with No Reward cautionary exp #107717

    J: 180lb, 65mg MAL dose (capsule) M: 130lb, 45mg MAL dose (capsule) Set and Setting: Both of us were excited to try MAL for the first time. The substance was tested with Mecke, Mandeline, and Marquis and was positively tested to be Methallylescaline HCl.

    ThePhoenix · Methallylescaline · 65 mg oral
    A Trip to the Hospital cautionary exp #105249

    [Erowid Note: The dose described in this report is very high, potentially beyond Erowid's 'heavy' range, and could pose serious health risks or result in unwanted, extreme effects.

    Used2BaboutRCs · Methallylescaline · 130 mg oral
    Bluelight 4 threads 4 neutral visit
    Methylallylescaline Mal Beginner Dancing In The Wind With Mal neutral

    Hi! I'm a long time (5+ year) lurker, it's about time I posted a TR. Early 30's female, 80kg (I'm tall) Moderate psychedelic experience. I generally prefer low doses, but have experimented with 10g mushrooms and 600ug LSD once each. Counting DMT, probably ~20-25 trips.

    scraped 2026-03-14
    Mal Methylallylescaline Experienced 25mg 5mg Rectal neutral

    MAL / METHYLALLYLESCALINE - 25mg + 5mg rectal - Second time by this ROA tl;dr - I've had many good experiences with MAL. This wasn't one of them. Nor was it a bad one. It was just an inexplicable, dull, gross nothingburger.

    scraped 2026-03-14
    Mal 38 Mg Moderately Experienced How Do I Use This neutral

    My apologies in advance for a lack of a rich narrative...the trip just wasn't that interesting (at least for the external observer), and I just want to get some information on this (somewhat rare) compound out there. I am a early-30 something male weighing roughly 80 kg.

    scraped 2026-03-14
    Mal 25mg First Time More Similar To Mesaline Than Different neutral

    I noticed a lack of reports on MAL on the internet, so I wrote this one up. Me: 140lb white male. 30 years old. Generally, my reactions to psychoactives are idiosyncratic, so I don't post them. There's not much use if you can't extrapolate from them.

    scraped 2026-03-14

    Bluelight Reference Guide Bluelight

    Phenethylamines The Big & Dandy Methallylescaline (MAL) Thread

    MethylAllylEscaline (MAL) Links: Wikipedia Page PiHKAL entry Pihkal Info MAL DOSAGE: 40 - 65 mg. DURATION: 12 - 16 h. QUALITATIVE COMMENTS: (with 45 mg) Too much overload. I am sur-rounded with unreality. I do not choose to repeat the experiment. (with 45 mg) I am basically favorably impressed.

    Read full thread on Bluelight β†’

    PiHKAL / TiHKAL Shulgin

    PiHKAL #99: MAL

    “Too much overload. I am surrounded with unreality. I do not choose to repeat the experiment.”

    β€” Alexander Shulgin, PiHKAL (with 45 mg)

    Helpful Links