Meclofenoxate Stats & Data
CN(C)CCOC(=O)COc1ccc(Cl)cc1XZTYGFHCIAKPGJ-UHFFFAOYSA-NPharmacology
DrugBankReceptor Profile
Receptor Actions
Toxicity
PsychonautWikiWarning: contraindications for Meclofenoxate include depression, mania, epilepsy and convulsions. Meclofenoxate is non-addictive, is not known to cause harm, and has an extremely low toxicity relative to dose. Similar to many other nootropic substances, there are relatively few physical side effects associated with acute choline exposure. Various studies have shown that in reasonable doses in a particular context, it presents no negative cognitive, psychiatric or toxic physical consequences of any sort. Regardless, it is strongly recommended that one is familiar with and uses harm reduction practices when using this substance.
Effect Profile
Curated + 1 ReportsModerate stimulation and focus with mild anxiety/jitters, low euphoria
Tolerance & Pharmacokinetics
drugs.wikiTolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Experience Report Analysis
ErowidDemographics
Gender Distribution
Reports Over Time
References
Cited References
- Alzheimer's Drug Discovery Foundation: Centrophenoxine Review
- Erowid: Meclofenoxate Vault
- Hochschild 1973: Effect on lifespan in mice
- Malík & Tlustoš 2022: Nootropics as Cognitive Enhancers
- Meclofenoxate DrugBank Entry
- Nootropics Expert: Centrophenoxine
- Stancheva & Alova: MAO inhibition study
- USADA: Meclofenoxate Information
- Vinmec: Uses of Lucimax
- SelfHacked: Centrophenoxine Guide